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1X9H
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BU of 1x9h by Molmil
Crystal structure of phosphoglucose/phosphomannose isomerase from Pyrobaculum aerophilum in complex with fructose 6-phosphate
Descriptor: FRUCTOSE -6-PHOSPHATE, GLYCEROL, SULFATE ION, ...
Authors:Swan, M.K, Hansen, T, Schoenheit, P, Davies, C.
Deposit date:2004-08-21
Release date:2004-12-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis for phosphomannose isomerase activity in phosphoglucose isomerase from Pyrobaculum aerophilum: a subtle difference between distantly related enzymes.
Biochemistry, 43, 2004
1DIV
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BU of 1div by Molmil
RIBOSOMAL PROTEIN L9
Descriptor: RIBOSOMAL PROTEIN L9
Authors:Hoffman, D.W, Cameron, C, Davies, C, Gerchman, S.E, Kycia, J.H, Porter, S, Ramakrishnan, V, White, S.W.
Deposit date:1996-07-02
Release date:1997-01-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of prokaryotic ribosomal protein L9: a bi-lobed RNA-binding protein.
EMBO J., 13, 1994
1NJ4
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BU of 1nj4 by Molmil
Crystal structure of a deacylation-defective mutant of penicillin-binding protein 5 at 1.9 A resolution
Descriptor: Penicillin-binding protein 5
Authors:Nicola, G, Nicholas, R.A, Davies, C.
Deposit date:2002-12-30
Release date:2003-01-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of wild-type penicillin-binding protein 5 from Escherichia coli: implications for deacylation of the acyl-enzyme complex.
J.Biol.Chem., 278, 2003
1NZO
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BU of 1nzo by Molmil
The crystal structure of wild type penicillin-binding protein 5 from E. coli
Descriptor: BETA-MERCAPTOETHANOL, Penicillin-binding protein 5
Authors:Nicholas, R.A, Krings, S, Tomberg, J, Nicola, G, Davies, C.
Deposit date:2003-02-19
Release date:2004-01-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of wild-type penicillin-binding protein 5 from Escherichia coli: implications for deacylation of the acyl-enzyme complex.
J.Biol.Chem., 278, 2003
1NZU
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BU of 1nzu by Molmil
Wild-type penicillin-binding protein 5 from E. coli modified by beta-mercaptoethanol
Descriptor: BETA-MERCAPTOETHANOL, Penicillin-binding protein 5
Authors:Nicola, G, Nicholas, R.A, Davies, C.
Deposit date:2003-02-19
Release date:2004-03-02
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:A large displacement of the SXN motif of Cys115-modified penicillin-binding protein 5 from Escherichia coli.
Biochem.J., 392, 2005
1QXJ
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BU of 1qxj by Molmil
Crystal structure of native phosphoglucose isomerase from Pyrococcus furiosus
Descriptor: Glucose-6-phosphate isomerase, NICKEL (II) ION
Authors:Swan, M.K, Solomons, J.T.G, Beeson, C.C, Hansen, T, Schonheit, P, Davies, C.
Deposit date:2003-09-07
Release date:2003-12-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural evidence for a hydride transfer mechanism of catalysis in phosphoglucose isomerase from Pyrococcus furiosus
J.Biol.Chem., 278, 2003
1QXR
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BU of 1qxr by Molmil
Crystal structure of phosphoglucose isomerase from Pyrococcus furiosus in complex with 5-phosphoarabinonate
Descriptor: 5-PHOSPHOARABINONIC ACID, Glucose-6-phosphate isomerase, NICKEL (II) ION
Authors:Swan, M.K, Solomons, J.T.G, Beeson, C.C, Hansen, P, Schonheit, P, Davies, C.
Deposit date:2003-09-08
Release date:2003-12-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural evidence for a hydride transfer mechanism of catalysis in phosphoglucose isomerase from Pyrococcus furiosus
J.Biol.Chem., 278, 2003
1QY4
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BU of 1qy4 by Molmil
Crystal structure of phosphoglucose isomerase from Pyrococcus furiosus in complex with gluconate 6-phosphate
Descriptor: 6-PHOSPHOGLUCONIC ACID, Glucose-6-phosphate isomerase, NICKEL (II) ION
Authors:Swan, M.K, Solomons, J.T.G, Beeson, C.C, Hansen, T, Schonheit, P, Davies, C.
Deposit date:2003-09-09
Release date:2003-12-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural evidence for a hydride transfer mechanism of catalysis in phosphoglucose isomerase from Pyrococcus furiosus
J.Biol.Chem., 278, 2003
1S3I
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BU of 1s3i by Molmil
Crystal structure of the N terminal hydrolase domain of 10-formyltetrahydrofolate dehydrogenase
Descriptor: 10-formyltetrahydrofolate dehydrogenase, BETA-MERCAPTOETHANOL
Authors:Chumanevich, A.A, Krupenko, S.A, Davies, C.
Deposit date:2004-01-13
Release date:2004-01-27
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase: mechanism of hydrolysis and its interplay with the dehydrogenase domain.
J.Biol.Chem., 279, 2004
6VBD
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BU of 6vbd by Molmil
Crystal structure of transpeptidase domain of PBP2 from Neisseria gonorrhoeae cephalosporin-resistant strain H041 acylated by ceftriaxone
Descriptor: CEFOTAXIME, C3' cleaved, open, ...
Authors:Singh, A, Davies, C.
Deposit date:2019-12-18
Release date:2020-04-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mutations in Neisseria gonorrhoeae penicillin-binding protein 2 associated with extended-spectrum cephalosporin resistance create an energetic barrier against acylation via restriction of protein dynamics
J.Biol.Chem., 2020
6VBL
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BU of 6vbl by Molmil
Crystal structure of the transpeptidase domain of PBP2 from the Neisseria gonorrhoeae cephalosporin decreased susceptibility strain 35/02
Descriptor: Probable peptidoglycan D,D-transpeptidase PenA
Authors:Singh, A, Davies, C.
Deposit date:2019-12-19
Release date:2020-04-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Mutations in Neisseria gonorrhoeae penicillin-binding protein 2 associated with extended-spectrum cephalosporin resistance create an energetic barrier against acylation via restriction of protein dynamics
J.Biol.Chem., 2020
3MZD
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BU of 3mzd by Molmil
Structure of penicillin-binding protein 5 from E. coli: cloxacillin acyl-enzyme complex
Descriptor: (2R,4S)-2-[(1S)-1-({[3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-2-oxoethyl]-5,5-dimethyl-1,3-thiazolid ine-4-carboxylic acid, D-alanyl-D-alanine carboxypeptidase dacA, GLYCEROL
Authors:Nicola, G, Tomberg, J, Pratt, R.F, Nicholas, R.A, Davies, C.
Deposit date:2010-05-12
Release date:2011-03-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of covalent complexes of beta-lactam antibiotics with Escherichia coli penicillin-binding protein 5: toward an understanding of antibiotic specificity
Biochemistry, 49, 2010
1TZC
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BU of 1tzc by Molmil
Crystal structure of phosphoglucose/phosphomannose isomerase from Pyrobaculum aerophilum in complex with 5-phosphoarabinonate
Descriptor: 5-PHOSPHOARABINONIC ACID, GLYCEROL, SULFATE ION, ...
Authors:Swan, M.K, Hansen, T, Schoenheit, P, Davies, C.
Deposit date:2004-07-09
Release date:2004-07-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:A novel phosphoglucose/phosphomannose isomease from the crenarchaeon Pyrobaculum aerophilum is a member of the PGI superfamily: structural evidence at 1.16 A resolution
J.Biol.Chem., 279, 2004
3MZE
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BU of 3mze by Molmil
Structure of penicillin-binding protein 5 from E.coli: cefoxitin acyl-enzyme complex
Descriptor: (2R)-5-[(carbamoyloxy)methyl]-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, D-alanyl-D-alanine carboxypeptidase dacA, GLYCEROL
Authors:Nicola, G, Tomberg, J, Pratt, R.F, Nicholas, R.A, Davies, C.
Deposit date:2010-05-12
Release date:2011-03-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of covalent complexes of beta-lactam antibiotics with Escherichia coli penicillin-binding protein 5: toward an understanding of antibiotic specificity
Biochemistry, 49, 2010
1TZB
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BU of 1tzb by Molmil
Crystal structure of native phosphoglucose/phosphomannose isomerase from Pyrobaculum aerophilum
Descriptor: GLYCEROL, SULFATE ION, glucose-6-phosphate isomerase, ...
Authors:Swan, M.K, Hansen, T, Schoenheit, P, Davies, C.
Deposit date:2004-07-09
Release date:2004-07-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:A novel phosphoglucose/phosphomannose isomease from the crenarchaeon Pyrobaculum aerophilum is a member of the PGI superfamily: structural evidence at 1.16 A resolution
J.Biol.Chem., 279, 2004
3UN7
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BU of 3un7 by Molmil
Crystal structure of PBPA from MYCOBACTERIUM TUBERCULOSIS
Descriptor: Penicillin-binding protein A
Authors:Fedarovich, A, Davies, C.
Deposit date:2011-11-15
Release date:2012-10-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The role of the beta5-alpha11 loop in the active-site dynamics of acylated penicillin-binding protein A from Mycobacterium tuberculosis
J.Mol.Biol., 418, 2012
6XQY
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BU of 6xqy by Molmil
Crystal structure of the catalytic domain of PBP2 S310A from Neisseria gonorrhoeae at pH 9.5
Descriptor: CHLORIDE ION, Probable peptidoglycan D,D-transpeptidase PenA
Authors:Fenton, B.A, Zhou, P, Davies, C.
Deposit date:2020-07-10
Release date:2021-07-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mutations in PBP2 from ceftriaxone-resistant Neisseria gonorrhoeae alter the dynamics of the beta 3-beta 4 loop to favor a low-affinity drug-binding state.
J.Biol.Chem., 297, 2021
6XQV
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BU of 6xqv by Molmil
Crystal structure of the catalytic domain of PBP2 S310A from Neisseria gonorrhoeae in a pre-acylation complex with ceftriaxone
Descriptor: CHLORIDE ION, Ceftriaxone, Probable peptidoglycan D,D-transpeptidase PenA, ...
Authors:Fenton, B.A, Zhou, P, Davies, C.
Deposit date:2020-07-10
Release date:2021-07-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Mutations in PBP2 from ceftriaxone-resistant Neisseria gonorrhoeae alter the dynamics of the beta 3-beta 4 loop to favor a low-affinity drug-binding state.
J.Biol.Chem., 297, 2021
6XQZ
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BU of 6xqz by Molmil
Crystal structure of the catalytic domain of PBP2 S310A from Neisseria gonorrhoeae at pH 7.5
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Peptidoglycan D,D-transpeptidase PenA, ...
Authors:Fenton, B.A, Zhou, P, Davies, C.
Deposit date:2020-07-10
Release date:2021-07-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Mutations in PBP2 from ceftriaxone-resistant Neisseria gonorrhoeae alter the dynamics of the beta 3-beta 4 loop to favor a low-affinity drug-binding state.
J.Biol.Chem., 297, 2021
6XQX
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BU of 6xqx by Molmil
Crystal structure of the catalytic domain of PBP2 S310A from Neisseria gonorrhoeae with the H514A mutation at pH 7.5
Descriptor: 1,2-ETHANEDIOL, Probable peptidoglycan D,D-transpeptidase PenA, SULFATE ION
Authors:Fenton, B.A, Zhou, P, Davies, C.
Deposit date:2020-07-10
Release date:2021-07-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Mutations in PBP2 from ceftriaxone-resistant Neisseria gonorrhoeae alter the dynamics of the beta 3-beta 4 loop to favor a low-affinity drug-binding state.
J.Biol.Chem., 297, 2021
5KSH
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BU of 5ksh by Molmil
Crystal structure of penicillin-binding protein 2 from Neisseria gonorrhoeae containing an A501T mutation associated with cephalosporin resistance
Descriptor: GLYCEROL, Penicillin-binding protein 2, SULFATE ION
Authors:Fedarovich, A, Davies, C.
Deposit date:2016-07-08
Release date:2017-03-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Alanine 501 Mutations in Penicillin-Binding Protein 2 from Neisseria gonorrhoeae: Structure, Mechanism, and Effects on Cephalosporin Resistance and Biological Fitness.
Biochemistry, 56, 2017
4B2G
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BU of 4b2g by Molmil
Crystal Structure of an Indole-3-Acetic Acid Amido Synthase from Vitis vinifera Involved in Auxin Homeostasis
Descriptor: GH3-1 AUXIN CONJUGATING ENZYME, MALONATE ION, [(2S,3R,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl] 2-(1H-indol-3-yl)ethyl hydrogen phosphate
Authors:Peat, T.S, Bottcher, C, Newman, J, Lucent, D, Cowieson, N, Davies, C.
Deposit date:2012-07-16
Release date:2012-12-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of an Indole-3-Acetic Acid Amido Synthetase from Grapevine Involved in Auxin Homeostasis.
Plant Cell, 24, 2012
3LO7
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BU of 3lo7 by Molmil
Crystal structure of PBPA from Mycobacterium tuberculosis
Descriptor: Penicillin-binding protein A
Authors:Fedarovich, A, Davies, C.
Deposit date:2010-02-03
Release date:2010-03-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Unusual conformation of the SxN motif in the crystal structure of penicillin-binding protein A from Mycobacterium tuberculosis.
J.Mol.Biol., 398, 2010
3MZF
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BU of 3mzf by Molmil
Structure of penicillin-binding protein 5 from E. coli: imipenem acyl-enzyme complex
Descriptor: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, D-alanyl-D-alanine carboxypeptidase dacA, GLYCEROL
Authors:Nicola, G, Tomberg, J, Pratt, R.F, Nicholas, R.A, Davies, C.
Deposit date:2010-05-12
Release date:2011-03-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structures of covalent complexes of beta-lactam antibiotics with Escherichia coli penicillin-binding protein 5: toward an understanding of antibiotic specificity
Biochemistry, 49, 2010
6P52
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BU of 6p52 by Molmil
Crystal structure of transpeptidase domain of PBP2 from Neisseria gonorrhoeae with a bound phosphate at the active site
Descriptor: PHOSPHATE ION, peptidoglycan D,D-transpeptidase PenA
Authors:Singh, A, Davies, C.
Deposit date:2019-05-29
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Recognition of the beta-lactam carboxylate triggers acylation ofNeisseria gonorrhoeaepenicillin-binding protein 2.
J.Biol.Chem., 294, 2019

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数据于2024-05-29公开中

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