6WU6
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![BU of 6wu6 by Molmil](/molmil-images/mine/6wu6) | succinate-coenzyme Q reductase | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Lyu, M, Su, C.-C, Morgan, C.E, Yu, E.W. | Deposit date: | 2020-05-04 | Release date: | 2021-02-03 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | A 'Build and Retrieve' methodology to simultaneously solve cryo-EM structures of membrane proteins. Nat.Methods, 18, 2021
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5K6U
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![BU of 5k6u by Molmil](/molmil-images/mine/5k6u) | Sidekick-1 immunoglobulin domains 1-4, crystal form 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CESIUM ION, IODIDE ION, ... | Authors: | Jin, X, Goodman, K.M, Mannepalli, S, Honig, B, Shapiro, L. | Deposit date: | 2016-05-25 | Release date: | 2016-09-28 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.201 Å) | Cite: | Molecular basis of sidekick-mediated cell-cell adhesion and specificity. Elife, 5, 2016
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1IRN
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![BU of 1irn by Molmil](/molmil-images/mine/1irn) | RUBREDOXIN (ZN-SUBSTITUTED) AT 1.2 ANGSTROMS RESOLUTION | Descriptor: | RUBREDOXIN, ZINC ION | Authors: | Dauter, Z, Wilson, K.S, Sieker, L.C, Moulis, J.M, Meyer, J. | Deposit date: | 1995-12-13 | Release date: | 1996-04-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Zinc- and iron-rubredoxins from Clostridium pasteurianum at atomic resolution: a high-precision model of a ZnS4 coordination unit in a protein. Proc.Natl.Acad.Sci.USA, 93, 1996
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1KAO
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![BU of 1kao by Molmil](/molmil-images/mine/1kao) | CRYSTAL STRUCTURE OF THE SMALL G PROTEIN RAP2A WITH GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAP2A | Authors: | Cherfils, J, Menetrey, J, Le Bras, G. | Deposit date: | 1997-08-01 | Release date: | 1997-12-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structures of the small G protein Rap2A in complex with its substrate GTP, with GDP and with GTPgammaS. EMBO J., 16, 1997
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6WIY
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![BU of 6wiy by Molmil](/molmil-images/mine/6wiy) | Crystal structure of Fab 54-1G05 | Descriptor: | Fab 54-1G05 heavy chain, Fab 54-1G05 light chain, GLYCEROL | Authors: | Wu, N.C, Wilson, I.A. | Deposit date: | 2020-04-11 | Release date: | 2020-07-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor. Cell Host Microbe, 28, 2020
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1L3U
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![BU of 1l3u by Molmil](/molmil-images/mine/1l3u) | Crystal Structure of Bacillus DNA Polymerase I Fragment product complex with 11 base pairs of duplex DNA following addition of a dTTP and a dATP residue. | Descriptor: | 5'-D(*GP*AP*C*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3', DNA Polymerase I, ... | Authors: | Johnson, S.J, Taylor, J.S, Beese, L.S. | Deposit date: | 2002-03-01 | Release date: | 2003-03-25 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Processive DNA synthesis observed in a polymerase crystal suggests a
mechanism for the prevention of frameshift mutations Proc.Natl.Acad.Sci.USA, 100, 2003
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1L5U
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![BU of 1l5u by Molmil](/molmil-images/mine/1l5u) | Crystal Structure of Bacillus DNA Polymerase I Fragment product complex with 12 base pairs of duplex DNA following addition of a dTTP, a dATP, and a dCTP residue. | Descriptor: | 5'-D(*GP*A*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*AP*C)-3', DNA Polymerase I, ... | Authors: | Johnson, S.J, Taylor, J.S, Beese, L.S. | Deposit date: | 2002-03-08 | Release date: | 2003-03-25 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Processive DNA synthesis observed in a polymerase crystal suggests a
mechanism for the prevention of frameshift mutations Proc.Natl.Acad.Sci.USA, 100, 2003
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2WKY
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![BU of 2wky by Molmil](/molmil-images/mine/2wky) | Crystal structure of the ligand-binding core of GluR5 in complex with the agonist 4-AHCP | Descriptor: | 3-(3-HYDROXY-7,8-DIHYDRO-6H-CYCLOHEPTA[D]ISOXAZOL-4-YL)-L-ALANINE, CHLORIDE ION, GLUTAMATE RECEPTOR, ... | Authors: | Naur, P, Gajhede, M, Kastrup, J.S. | Deposit date: | 2009-06-18 | Release date: | 2009-07-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Glutamate Receptor Glur5 Agonist (S)-2-Amino-3-(3-Hydroxy-7,8-Dihydro-6H-Cyclohepta[D]Isoxazol-4-Yl)Propionic Acid and the 8-Methyl Analogue: Synthesis, Molecular Pharmacology, and Biostructural Characterization J.Med.Chem., 52, 2009
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1LD8
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![BU of 1ld8 by Molmil](/molmil-images/mine/1ld8) | Co-crystal structure of Human Farnesyltransferase with farnesyldiphosphate and inhibitor compound 49 | Descriptor: | (20S)-19,20,21,22-TETRAHYDRO-19-OXO-5H-18,20-ETHANO-12,14-ETHENO-6,10-METHENO-18H-BENZ[D]IMIDAZO[4,3-K][1,6,9,12]OXATRI AZA-CYCLOOCTADECOSINE-9-CARBONITRILE, ACETIC ACID, FARNESYL DIPHOSPHATE, ... | Authors: | Taylor, J.S, Terry, K.L, Beese, L.S. | Deposit date: | 2002-04-08 | Release date: | 2002-06-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | 3-Aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency. J.Med.Chem., 45, 2002
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1L3S
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![BU of 1l3s by Molmil](/molmil-images/mine/1l3s) | Crystal Structure of Bacillus DNA Polymerase I Fragment complexed to 9 base pairs of duplex DNA. | Descriptor: | 5'-D(*GP*A*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*G)-3', DNA Polymerase I, ... | Authors: | Johnson, S.J, Taylor, J.S, Beese, L.S. | Deposit date: | 2002-03-01 | Release date: | 2003-03-25 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Processive DNA synthesis observed in a polymerase crystal suggests a
mechanism for the prevention of frameshift mutations Proc.Natl.Acad.Sci.USA, 100, 2003
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1LK2
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![BU of 1lk2 by Molmil](/molmil-images/mine/1lk2) | 1.35A crystal structure of H-2Kb complexed with the GNYSFYAL peptide | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Luz, J.G, Rudolph, M.G, Wilson, I.A, Eisen, H. | Deposit date: | 2002-04-23 | Release date: | 2003-11-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | A peptide that antagonizes TCR-mediated reactions with both syngeneic and allogeneic agonists: functional and structural aspects. J.Immunol., 172, 2004
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2QQS
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![BU of 2qqs by Molmil](/molmil-images/mine/2qqs) | |
1LD7
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![BU of 1ld7 by Molmil](/molmil-images/mine/1ld7) | Co-crystal structure of Human Farnesyltransferase with farnesyldiphosphate and inhibitor compound 66 | Descriptor: | (20S)-19,20,22,23-TETRAHYDRO-19-OXO-5H,21H-18,20-ETHANO-12,14-ETHENO-6,10-METHENOBENZ[D]IMIDAZO[4,3-L][1,6,9,13]OXATRIA ZACYCLONOADECOSINE-9-CARBONITRILE, FARNESYL DIPHOSPHATE, ZINC ION, ... | Authors: | Taylor, J.S, Terry, K.L, Beese, L.S. | Deposit date: | 2002-04-08 | Release date: | 2002-06-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | 3-Aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency. J.Med.Chem., 45, 2002
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1LEC
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![BU of 1lec by Molmil](/molmil-images/mine/1lec) | STRUCTURES OF THE LECTIN IV OF GRIFFONIA SIMPLICIFOLIA AND ITS COMPLEX WITH THE LEWIS B HUMAN BLOOD GROUP DETERMINANT AT 2.0 ANGSTROMS RESOLUTION | Descriptor: | CALCIUM ION, MANGANESE (II) ION, SULFATE ION, ... | Authors: | Delbaere, L, Vandonselaar, M, Quail, J. | Deposit date: | 1992-12-17 | Release date: | 1994-01-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of the lectin IV of Griffonia simplicifolia and its complex with the Lewis b human blood group determinant at 2.0 A resolution. J.Mol.Biol., 230, 1993
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2RAP
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![BU of 2rap by Molmil](/molmil-images/mine/2rap) | THE SMALL G PROTEIN RAP2A IN COMPLEX WITH GTP | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RAP2A | Authors: | Cherfils, J, Menetrey, J, Lebras, G. | Deposit date: | 1998-05-06 | Release date: | 1998-06-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structures of the small G protein Rap2A in complex with its substrate GTP, with GDP and with GTPgammaS. EMBO J., 16, 1997
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1L3V
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![BU of 1l3v by Molmil](/molmil-images/mine/1l3v) | Crystal Structure of Bacillus DNA Polymerase I Fragment product complex with 15 base pairs of duplex DNA following addition of dTTP, dATP, dCTP, and dGTP residues. | Descriptor: | 5'-D(*GP*AP*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*AP*CP*GP*TP*C)-3', DNA Polymerase I, ... | Authors: | Johnson, S.J, Taylor, J.S, Beese, L.S. | Deposit date: | 2002-03-01 | Release date: | 2003-03-25 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Processive DNA synthesis observed in a polymerase crystal suggests a
mechanism for the prevention of frameshift mutations Proc.Natl.Acad.Sci.USA, 100, 2003
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2QFO
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![BU of 2qfo by Molmil](/molmil-images/mine/2qfo) | HSP90 complexed with A143571 and A516383 | Descriptor: | (3E)-3-[(phenylamino)methylidene]dihydrofuran-2(3H)-one, 4-METHYL-6-(TRIFLUOROMETHYL)PYRIMIDIN-2-AMINE, Heat shock protein HSP 90-alpha | Authors: | Park, C.H. | Deposit date: | 2007-06-27 | Release date: | 2008-07-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Discovery and design of novel HSP90 inhibitors using multiple fragment-based design strategies. CHEM.BIOL.DRUG DES., 70, 2007
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2QQ7
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![BU of 2qq7 by Molmil](/molmil-images/mine/2qq7) | Crystal structure of drug resistant SRC kinase domain with irreversible inhibitor | Descriptor: | (2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide, Proto-oncogene tyrosine-protein kinase Src | Authors: | Michalczyk, A, Rode, H.B, Gruetter, C, Rauh, D. | Deposit date: | 2007-07-26 | Release date: | 2008-03-11 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Structural insights into how irreversible inhibitors can overcome drug resistance in EGFR. Bioorg.Med.Chem., 16, 2008
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2QI8
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![BU of 2qi8 by Molmil](/molmil-images/mine/2qi8) | Crystal structure of drug resistant SRC kinase domain | Descriptor: | GLYCEROL, Proto-oncogene tyrosine-protein kinase Src | Authors: | Michalczyk, A, Rode, H.B, Gruetter, C, Rauh, D. | Deposit date: | 2007-07-03 | Release date: | 2008-03-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Structural insights into how irreversible inhibitors can overcome drug resistance in EGFR. Bioorg.Med.Chem., 16, 2008
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2QV4
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![BU of 2qv4 by Molmil](/molmil-images/mine/2qv4) | Human pancreatic alpha-amylase complexed with nitrite and acarbose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4,6-dideoxy-4-{[(1S,4R,5R,6S)-4-{[alpha-D-glucopyranosyl-(1->4)-alpha-D-glucopyranosyl-(1->4)-alpha-D-glucopyranosyl]oxy}-5,6-dihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose, CALCIUM ION, ... | Authors: | Williams, L.K, Maurus, R, Brayer, G.D. | Deposit date: | 2007-08-07 | Release date: | 2008-03-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity Biochemistry, 47, 2008
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1L8A
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![BU of 1l8a by Molmil](/molmil-images/mine/1l8a) | E. COLI PYRUVATE DEHYDROGENASE | Descriptor: | MAGNESIUM ION, Pyruvate dehydrogenase E1 component, THIAMINE DIPHOSPHATE | Authors: | Furey, W, Arjunan, P. | Deposit date: | 2002-03-19 | Release date: | 2002-07-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure of the pyruvate dehydrogenase multienzyme complex E1 component from Escherichia coli at 1.85 A resolution. Biochemistry, 41, 2002
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1IRO
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![BU of 1iro by Molmil](/molmil-images/mine/1iro) | RUBREDOXIN (OXIDIZED, FE(III)) AT 1.1 ANGSTROMS RESOLUTION | Descriptor: | FE (III) ION, RUBREDOXIN | Authors: | Dauter, Z, Wilson, K.S, Sieker, L.C, Moulis, J.M, Meyer, J. | Deposit date: | 1995-12-13 | Release date: | 1996-04-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Zinc- and iron-rubredoxins from Clostridium pasteurianum at atomic resolution: a high-precision model of a ZnS4 coordination unit in a protein. Proc.Natl.Acad.Sci.USA, 93, 1996
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1L3T
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![BU of 1l3t by Molmil](/molmil-images/mine/1l3t) | Crystal Structure of Bacillus DNA Polymerase I Fragment product complex with 10 base pairs of duplex DNA following addition of a single dTTP residue | Descriptor: | 5'-D(*GP*AP*CP*G*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3', DNA Polymerase I, ... | Authors: | Johnson, S.J, Taylor, J.S, Beese, L.S. | Deposit date: | 2002-03-01 | Release date: | 2003-03-25 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Processive DNA synthesis observed in a polymerase crystal suggests a
mechanism for the prevention of frameshift mutations Proc.Natl.Acad.Sci.USA, 100, 2003
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1LES
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![BU of 1les by Molmil](/molmil-images/mine/1les) | LENTIL LECTIN COMPLEXED WITH SUCROSE | Descriptor: | CALCIUM ION, LENTIL LECTIN, MANGANESE (II) ION, ... | Authors: | Hamelryck, T, Loris, R. | Deposit date: | 1995-08-23 | Release date: | 1995-12-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | NMR, molecular modeling, and crystallographic studies of lentil lectin-sucrose interaction. J.Biol.Chem., 270, 1995
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1LED
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![BU of 1led by Molmil](/molmil-images/mine/1led) | STRUCTURES OF THE LECTIN IV OF GRIFFONIA SIMPLICIFOLIA AND ITS COMPLEX WITH THE LEWIS B HUMAN BLOOD GROUP DETERMINANT AT 2.0 ANGSTROMS RESOLUTION | Descriptor: | CALCIUM ION, MANGANESE (II) ION, SULFATE ION, ... | Authors: | Delbaere, L, Vandonselaar, M, Quail, J. | Deposit date: | 1992-12-17 | Release date: | 1994-01-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of the lectin IV of Griffonia simplicifolia and its complex with the Lewis b human blood group determinant at 2.0 A resolution. J.Mol.Biol., 230, 1993
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