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1RHM
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BU of 1rhm by Molmil
CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-3 WITH A NICOTINIC ACID ALDEHYDE INHIBITOR
Descriptor: 4-[5-(2-CARBOXY-1-FORMYL-ETHYLCARBAMOYL)-PYRIDIN-3-YL]-BENZOIC ACID, CASP-3
Authors:Becker, J.W, Rotonda, J, Soisson, S.M.
Deposit date:2003-11-14
Release date:2004-05-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Reducing the Peptidyl Features of Caspase-3 Inhibitors: A Structural Analysis.
J.Med.Chem., 47, 2004
1RHK
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BU of 1rhk by Molmil
Crystal structure of the complex of caspase-3 with a phenyl-propyl-ketone inhibitor
Descriptor: Caspase-3, acetyl-asp-glu-val-fpr
Authors:Becker, J.W, Rotonda, J, Soisson, S.M.
Deposit date:2003-11-14
Release date:2004-05-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Reducing the Peptidyl Features of Caspase-3 Inhibitors: A Structural Analysis.
J.Med.Chem., 47, 2004
1RHR
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BU of 1rhr by Molmil
CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-3 WITH A CINNAMIC ACID METHYL ESTER INHIBITOR
Descriptor: (3S)-5-[(2-CHLORO-6-FLUOROBENZYL)SULFANYL]-3-{[N-({2-ETHOXY-5-[(1E)-3-METHOXY-3-OXOPROP-1-ENYL]PHENYL}ACETYL)-D-VALYL]AMINO}-4-OXOPENTANOIC ACID, Caspase-3
Authors:Becker, J.W, Rotonda, J, Soisson, S.M.
Deposit date:2003-11-14
Release date:2004-05-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Reducing the Peptidyl Features of Caspase-3 Inhibitors: A Structural Analysis.
J.Med.Chem., 47, 2004
1RHJ
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BU of 1rhj by Molmil
CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-3 WITH A PRYAZINONE INHIBITOR
Descriptor: 3-(2-{5-TERT-BUTYL-3-[(4-METHYL-FURAZAN-3-YLMETHYL)-AMINO]-2-OXO-2H-PYRAZIN-1-YL}-BUTYRYLAMINO)-5-(HEXYL-METHYL-AMINO)-4-OXO-PENTANOIC ACID ANION, Caspase-3
Authors:Becker, J.W, Rotonda, J, Soisson, S.M.
Deposit date:2003-11-14
Release date:2004-05-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Reducing the Peptidyl Features of Caspase-3 Inhibitors: A Structural Analysis.
J.Med.Chem., 47, 2004
2GCJ
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BU of 2gcj by Molmil
Crystal Structure of the Pob3 middle domain
Descriptor: Hypothetical 63.0 kDa protein in DAK1-ORC1 intergenic region
Authors:VanDemark, A.P.
Deposit date:2006-03-14
Release date:2006-05-23
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The Structure of the yFACT Pob3-M Domain, Its Interaction with the DNA Replication Factor RPA, and a Potential Role in Nucleosome Deposition.
Mol.Cell, 22, 2006
2ECS
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BU of 2ecs by Molmil
Lambda Cro mutant Q27P/A29S/K32Q at 1.4 A in space group C2
Descriptor: ACETATE ION, CHLORIDE ION, LITHIUM ION, ...
Authors:Hall, B.M, Roberts, S.A, Cordes, M.H.
Deposit date:2007-02-14
Release date:2008-01-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Two structures of a lambda Cro variant highlight dimer flexibility but disfavor major dimer distortions upon specific binding of cognate DNA.
J.Mol.Biol., 375, 2008
1Z3Y
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BU of 1z3y by Molmil
Structure of Gun4-1 from Thermosynechococcus elongatus
Descriptor: putative cytidylyltransferase
Authors:Davison, P.A, Schubert, H.L, Reid, J.D, Iorg, C.D, Robinson, H, Hill, C.P, Hunter, C.N.
Deposit date:2005-03-14
Release date:2005-06-07
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and Biochemical Characterization of Gun4 Suggests a Mechanism for Its Role in Chlorophyll Biosynthesis(,).
Biochemistry, 44, 2005
1Z3X
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BU of 1z3x by Molmil
Structure of Gun4 from Thermosynechococcus elongatus
Descriptor: putative cytidylyltransferase
Authors:Davison, P.A, Schubert, H.L, Reid, J.D, Iorg, C.D, Robinson, H, Hill, C.P, Hunter, C.N.
Deposit date:2005-03-14
Release date:2005-06-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural and Biochemical Characterization of Gun4 Suggests a Mechanism for Its Role in Chlorophyll Biosynthesis(,).
Biochemistry, 44, 2005
3JSE
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BU of 3jse by Molmil
Crystal structure of archaeal 20S proteasome in complex with mutated P26 activator
Descriptor: Proteasome activator protein PA26, Proteasome subunit alpha, Proteasome subunit beta
Authors:Stadtmueller, B.M, Whitby, F.G, Hill, C.P.
Deposit date:2009-09-10
Release date:2009-11-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural models for interactions between the 20S proteasome and its PAN/19S activators.
J.Biol.Chem., 285, 2010
3JTL
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BU of 3jtl by Molmil
Crystal structure of archaeal 20S proteasome in complex with mutated P26 activator
Descriptor: Proteasome activator protein PA26, Proteasome subunit alpha, Proteasome subunit beta
Authors:Stadtmueller, B.M, Whitby, F.G, Hill, C.P.
Deposit date:2009-09-12
Release date:2009-11-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Models for Interactions between the 20S proteasome and its PAN/19S activators.
J.Biol.Chem., 285, 2010
3K0X
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BU of 3k0x by Molmil
Crystal structure of telomere capping protein Ten1 from Saccharomyces pombe
Descriptor: IODIDE ION, Protein Ten1
Authors:Gelinas, A.D, Reyes, F.E, Batey, R.T, Wuttke, D.S.
Deposit date:2009-09-25
Release date:2009-10-27
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain.
Proc.Natl.Acad.Sci.USA, 106, 2009
3LZS
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BU of 3lzs by Molmil
Crystal Structure of HIV-1 CRF01_AE Protease in Complex with Darunavir
Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETATE ION, HIV-1 protease
Authors:Schiffer, C.A, Bandaranayake, R.M.
Deposit date:2010-03-01
Release date:2010-08-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Effect of Clade-Specific Sequence Polymorphisms on HIV-1 Protease Activity and Inhibitor Resistance Pathways.
J.Virol., 84, 2010
3LZU
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BU of 3lzu by Molmil
Crystal Structure of a Nelfinavir Resistant HIV-1 CRF01_AE Protease variant (N88S) in Complex with the Protease Inhibitor Darunavir.
Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETATE ION, HIV-1 protease
Authors:Schiffer, C.A, Bandaranayake, R.M.
Deposit date:2010-03-01
Release date:2010-08-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:The Effect of Clade-Specific Sequence Polymorphisms on HIV-1 Protease Activity and Inhibitor Resistance Pathways.
J.Virol., 84, 2010
3LZV
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BU of 3lzv by Molmil
Structure of Nelfinavir-resistant HIV-1 protease (D30N/N88D) in complex with Darunavir.
Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETATE ION, HIV-1 Protease, ...
Authors:Schiffer, C.A, Kolli, M.
Deposit date:2010-03-01
Release date:2010-08-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The Effect of Clade-Specific Sequence Polymorphisms on HIV-1 Protease Activity and Inhibitor Resistance Pathways.
J.Virol., 84, 2010
4I6M
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BU of 4i6m by Molmil
Structure of Arp7-Arp9-Snf2(HSA)-RTT102 subcomplex of SWI/SNF chromatin remodeler.
Descriptor: Actin-like protein ARP9, Actin-related protein 7, PHOSPHATE ION, ...
Authors:Schubert, H.L, Cairns, B.R, Hill, C.P.
Deposit date:2012-11-29
Release date:2013-02-13
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Structure of an actin-related subcomplex of the SWI/SNF chromatin remodeler.
Proc.Natl.Acad.Sci.USA, 110, 2013
3THF
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BU of 3thf by Molmil
Crystal structure of the SD2 domain from Drosophila Shroom
Descriptor: Protein Shroom
Authors:Mohan, S, VanDemark, A.P.
Deposit date:2011-08-18
Release date:2012-06-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6951 Å)
Cite:Structure of Shroom domain 2 reveals a three-segmented coiled-coil required for dimerization, Rock binding, and apical constriction.
Mol Biol Cell, 23, 2012
3SZM
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BU of 3szm by Molmil
STRUCTURE OF HUMAN MICROCEPHALIN (MCPH1) TANDEM BRCT DOMAINS IN COMPLEX WITH A GAMMA-H2AX PHOSPHOPEPTIDE
Descriptor: Histone H2A.x, Microcephalin
Authors:Singh, N, Thompson, J.R, Mer, G.
Deposit date:2011-07-19
Release date:2011-11-30
Last modified:2012-09-19
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1.
Proc.Natl.Acad.Sci.USA, 109, 2012
3CWE
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BU of 3cwe by Molmil
PTP1B in complex with a phosphonic acid inhibitor
Descriptor: MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 1, [{2-bromo-4-[(2R)-3-oxo-2,3-diphenylpropyl]phenyl}(difluoro)methyl]phosphonic acid
Authors:Scapin, G, Han, Y, Kennedy, B.P.
Deposit date:2008-04-21
Release date:2008-06-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Discovery of [(3-bromo-7-cyano-2-naphthyl)(difluoro)methyl]phosphonic acid, a potent and orally active small molecule PTP1B inhibitor
Bioorg.Med.Chem.Lett., 18, 2008
4IQ2
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BU of 4iq2 by Molmil
P21 crystal form of FKBP12.6
Descriptor: MALONIC ACID, Peptidyl-prolyl cis-trans isomerase FKBP1B
Authors:Chen, H, Mustafi, S.M, Li, H.M, LeMaster, D.M, Hernandez, G.
Deposit date:2013-01-10
Release date:2014-01-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6.
Acta Crystallogr.,Sect.D, 70, 2014
4IQC
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BU of 4iqc by Molmil
P3121 crystal form of FKBP12.6
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B
Authors:Chen, H, Mustafi, S.M, Li, H.M, LeMaster, D.M, Hernandez, G.
Deposit date:2013-01-11
Release date:2014-01-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6.
Acta Crystallogr.,Sect.D, 70, 2014
3D8N
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BU of 3d8n by Molmil
Uroporphyrinogen III Synthase-Uroporphyringen III Complex
Descriptor: 3,3',3'',3'''-[3,8,13,17-tetrakis(carboxymethyl)porphyrin-2,7,12,18-tetrayl]tetrapropanoic acid, Uroporphyrinogen-III synthase
Authors:Schubert, H.L.
Deposit date:2008-05-23
Release date:2008-08-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and mechanistic implications of a uroporphyrinogen III synthase-product complex.
Biochemistry, 47, 2008
3D8T
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BU of 3d8t by Molmil
Thermus thermophilus Uroporphyrinogen III Synthase
Descriptor: ACETATE ION, Uroporphyrinogen-III synthase
Authors:Schubert, H.L.
Deposit date:2008-05-23
Release date:2008-08-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure and mechanistic implications of a uroporphyrinogen III synthase-product complex.
Biochemistry, 47, 2008
3D8S
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BU of 3d8s by Molmil
Thermus thermophilus Uroporphyrinogen III Synthase
Descriptor: GLYCEROL, Uroporphyrinogen-III synthase
Authors:Schubert, H.L.
Deposit date:2008-05-23
Release date:2008-08-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and mechanistic implications of a uroporphyrinogen III synthase-product complex.
Biochemistry, 47, 2008
4L2W
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BU of 4l2w by Molmil
Crystal structure of the Shroom-Binding domain of human Rock1
Descriptor: Rho-associated protein kinase 1
Authors:Mohan, S, VanDemark, A.P.
Deposit date:2013-06-04
Release date:2014-04-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structure of a highly conserved domain of Rock1 required for Shroom-mediated regulation of cell morphology.
Plos One, 8, 2013
3V46
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BU of 3v46 by Molmil
Crystal Structure of Yeast Cdc73 C-Terminal Domain
Descriptor: Cell division control protein 73
Authors:Amrich, C.G, VanDemark, A.P.
Deposit date:2011-12-14
Release date:2012-02-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.549 Å)
Cite:Cdc73 subunit of Paf1 complex contains C-terminal Ras-like domain that promotes association of Paf1 complex with chromatin.
J.Biol.Chem., 287, 2012

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数据于2024-06-26公开中

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