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5XM2
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BU of 5xm2 by Molmil
Human N-terminal domain of FACT complex subunit SPT16
Descriptor: DI(HYDROXYETHYL)ETHER, FACT complex subunit SPT16, GLYCEROL
Authors:Xu, S, Li, H, Dou, Y, Chen, Y, Jiang, H, Lu, D, Wang, M, Su, D.
Deposit date:2017-05-12
Release date:2018-05-16
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.187 Å)
Cite:The structural basis of human Spt16 N-terminal domain interaction with histone (H3-H4)2tetramer.
Biochem.Biophys.Res.Commun., 508, 2019
5ZFZ
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BU of 5zfz by Molmil
Crystal structure of human DUX4 homeodomains bound to A12T DNA mutant
Descriptor: DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*TP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*AP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4-like protein 4
Authors:Li, Y.Y, Wu, B.X, Gan, J.H.
Deposit date:2018-03-07
Release date:2018-10-31
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for multiple gene regulation by human DUX4.
Biochem. Biophys. Res. Commun., 505, 2018
5ZFW
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BU of 5zfw by Molmil
Crystal structure of human DUX4 homeodomains bound to A11G DNA mutant
Descriptor: DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*GP*AP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*TP*CP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4-like protein 4
Authors:Li, Y.Y, Wu, B.X, Gan, J.H.
Deposit date:2018-03-07
Release date:2018-10-31
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:Structural basis for multiple gene regulation by human DUX4.
Biochem. Biophys. Res. Commun., 505, 2018
5ZFY
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BU of 5zfy by Molmil
Crystal structure of human DUX4 homeodomains bound to A12C DNA mutant
Descriptor: DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*CP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*GP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4-like protein 4
Authors:Li, Y.Y, Wu, B.X, Gan, J.H.
Deposit date:2018-03-07
Release date:2018-10-31
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for multiple gene regulation by human DUX4.
Biochem. Biophys. Res. Commun., 505, 2018
5Z6Z
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BU of 5z6z by Molmil
Crystal structure of human DUX4 homeodomains bound to DNA
Descriptor: DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*AP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*TP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4
Authors:Li, Y.Y, Wu, B.X, Gan, J.H.
Deposit date:2018-01-26
Release date:2018-10-31
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Structural basis for multiple gene regulation by human DUX4.
Biochem. Biophys. Res. Commun., 505, 2018
2JK7
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BU of 2jk7 by Molmil
XIAP BIR3 bound to a Smac Mimetic
Descriptor: (3S,6S,7Z,10AS)-N-(DIPHENYLMETHYL)-6-{[(2S)-2-(METHYLIDENEAMINO)BUTANOYL]AMINO}-5-OXO-1,2,3,5,6,9,10,10A-OCTAHYDROPYRROLO[1,2-A]AZOCINE-3-CARBOXAMIDE, BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 4, ZINC ION
Authors:Saito, N.G, Meagher, J.L, Stuckey, J.A.
Deposit date:2008-08-21
Release date:2008-11-04
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Structure-Based Design, Synthesis, Evaluation, and Crystallographic Studies of Conformationally Constrained Smac Mimetics as Inhibitors of the X-Linked Inhibitor of Apoptosis Protein (Xiap).
J.Med.Chem., 51, 2008
7CLZ
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BU of 7clz by Molmil
Crystal structure of Alp1U W187F/Y247F in complex with fluostatin C
Descriptor: BORIC ACID, D-MALATE, Fluostatin C, ...
Authors:Zhang, L, De, B.C.
Deposit date:2020-07-22
Release date:2020-10-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.10001016 Å)
Cite:Mutation of an atypical oxirane oxyanion hole improves regioselectivity of the alpha / beta-fold epoxide hydrolase Alp1U.
J.Biol.Chem., 295, 2020
6JV0
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BU of 6jv0 by Molmil
Crystal Structure of N-terminal domain of ArgZ, bound to Product, an arginine dihydrolase from the Ornithine-Ammonia Cycle in Cyanobacteria
Descriptor: 1,2-ETHANEDIOL, L-ornithine, Sll1336 protein
Authors:Zhuang, N, Li, L, Wu, X, Zhang, Y.
Deposit date:2019-04-15
Release date:2020-01-15
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Crystal structures and biochemical analyses of the bacterial arginine dihydrolase ArgZ suggests a "bond rotation" catalytic mechanism.
J.Biol.Chem., 295, 2020
6JV1
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BU of 6jv1 by Molmil
Crystal Structure of N-terminal domain of ArgZ, C264S mutant, bound to Substrate, an arginine dihydrolase from the Ornithine-Ammonia Cycle in Cyanobacteria
Descriptor: ARGININE, Sll1336 protein
Authors:Zhuang, N, Li, L, Wu, X, Zhang, Y.
Deposit date:2019-04-15
Release date:2020-01-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal structures and biochemical analyses of the bacterial arginine dihydrolase ArgZ suggests a "bond rotation" catalytic mechanism.
J.Biol.Chem., 295, 2020
6JUY
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BU of 6juy by Molmil
Crystal Structure of ArgZ, apo structure, an Arginine Dihydrolase from the Ornithine-Ammonia Cycle in Cyanobacteria
Descriptor: Sll1336 protein
Authors:Zhuang, N, Li, L, Wu, X, Zhang, Y.
Deposit date:2019-04-15
Release date:2020-01-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Crystal structures and biochemical analyses of the bacterial arginine dihydrolase ArgZ suggests a "bond rotation" catalytic mechanism.
J.Biol.Chem., 295, 2020
6KHY
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BU of 6khy by Molmil
The crystal structure of AsfvAP:AG
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (AGCGTCACCGACGAGGC), DNA(AGCGTCACCGACGAGG), ...
Authors:Chen, Y.Q, Gan, J.H.
Deposit date:2019-07-16
Release date:2020-06-03
Method:X-RAY DIFFRACTION (3.008 Å)
Cite:A unique DNA-binding mode of African swine fever virus AP endonuclease.
Cell Discov, 6, 2020
6JUZ
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BU of 6juz by Molmil
Crystal Structure of N-terminal domain of ArgZ(N71S) covalently bond to a reaction intermediate
Descriptor: 1,2-ETHANEDIOL, ARGININE, Sll1336 protein
Authors:Zhuang, N, Li, L, Wu, X, Zhuang, Y.
Deposit date:2019-04-15
Release date:2020-01-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Crystal structures and biochemical analyses of the bacterial arginine dihydrolase ArgZ suggests a "bond rotation" catalytic mechanism.
J.Biol.Chem., 295, 2020
6KI3
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BU of 6ki3 by Molmil
The crystal structure of AsfvAP:dF commplex
Descriptor: DNA (5'-D(*CP*CP*TP*CP*GP*TP*CP*GP*GP*GP*GP*AP*CP*GP*CP*TP*G)-3'), DNA (5'-D(*GP*CP*AP*GP*CP*GP*TP*CP*C)-3'), DNA (5'-D(P*(3DR)P*CP*GP*AP*CP*GP*AP*G)-3'), ...
Authors:Chen, Y, Gan, J.
Deposit date:2019-07-17
Release date:2020-05-27
Method:X-RAY DIFFRACTION (2.354 Å)
Cite:A unique DNA-binding mode of African swine fever virus AP endonuclease.
Cell Discov, 6, 2020
1LLC
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BU of 1llc by Molmil
STRUCTURE DETERMINATION OF THE ALLOSTERIC L-LACTATE DEHYDROGENASE FROM LACTOBACILLUS CASEI AT 3.0 ANGSTROMS RESOLUTION
Descriptor: 1,6-di-O-phosphono-alpha-D-fructofuranose, L-LACTATE DEHYDROGENASE, SULFATE ION
Authors:Buehner, M, Hecht, H.J, Hensel, R.
Deposit date:1988-11-21
Release date:1989-07-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:STRUCTURE DETERMINATION OF THE ALLOSTERIC L-LACTATE DEHYDROGENASE FROM LACTOBACILLUS-CASEI AT 3A RESOLUTION.
Acta Crystallogr.,Sect.A, 40, 1984
7EAM
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BU of 7eam by Molmil
immune complex of SARS-CoV-2 RBD and cross-neutralizing antibody 7D6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ...
Authors:Li, T.T, Gu, Y, Li, S.W.
Deposit date:2021-03-07
Release date:2021-03-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants.
Nat Commun, 12, 2021
7VBS
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BU of 7vbs by Molmil
Structure of the AAA+ ATPase domain of the transcriptional regulator GtrR in Burkholderia cenocepacia
Descriptor: PHOSPHATE ION, Sigma-54 dependent trancsriptional regulator
Authors:Yan, X.F, Yong, Y, Gao, Y.G.
Deposit date:2021-09-01
Release date:2021-12-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:Structural analyses of the AAA+ ATPase domain of the transcriptional regulator GtrR in the BDSF quorum-sensing system in Burkholderia cenocepacia.
Febs Lett., 596, 2022
7VBW
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BU of 7vbw by Molmil
Structure of the GTP-bound AAA+ ATPase domain of the transcriptional regulator GtrR in Burkholderia cenocepacia
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Sigma-54 dependent trancsriptional regulator
Authors:Yan, X.F, Yong, Y, Gao, Y.G.
Deposit date:2021-09-01
Release date:2021-12-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural analyses of the AAA+ ATPase domain of the transcriptional regulator GtrR in the BDSF quorum-sensing system in Burkholderia cenocepacia.
Febs Lett., 596, 2022
7YGG
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BU of 7ygg by Molmil
Crystal structure of human CD47 in complex with engineered SIRPa.D1(N80A)
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Leukocyte surface antigen CD47, ...
Authors:Yu, J, Tian, W.
Deposit date:2022-07-11
Release date:2022-10-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Crystal Structure of Human CD47 in Complex with Engineered SIRP alpha.D1(N80A).
Molecules, 27, 2022
7D3M
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BU of 7d3m by Molmil
FOOT AND MOUTH DISEASE VIRUS O/TIBET/99-BOUND THE SINGLE CHAIN FRAGMEN ANTIBODY R50
Descriptor: O/TIBET/99 VP1, O/TIBET/99 VP2, O/TIBET/99 VP3, ...
Authors:He, Y, Lou, Z.
Deposit date:2020-09-19
Release date:2021-04-14
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (3.94 Å)
Cite:Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization.
Plos Pathog., 17, 2021
7D3K
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BU of 7d3k by Molmil
FOOT AND MOUTH DISEASE VIRUS O/TIBET/99-BOUND THE SINGLE CHAIN FRAGMEN ANTIBODY B77
Descriptor: B77 VH, B77 VL, O/TIBET/99 VP1, ...
Authors:He, Y, Lou, Z.
Deposit date:2020-09-19
Release date:2021-04-14
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization.
Plos Pathog., 17, 2021
7D3L
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BU of 7d3l by Molmil
FOOT AND MOUTH DISEASE VIRUS O/TIBET/99-BOUND THE SINGLE CHAIN FRAGMEN ANTIBODY F145
Descriptor: F145 VH, F145 VL, O/TIBET/99 VP1, ...
Authors:He, Y, Lou, Z.
Deposit date:2020-09-19
Release date:2021-04-14
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization.
Plos Pathog., 17, 2021
7D3R
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BU of 7d3r by Molmil
FOOT AND MOUTH DISEASE VIRUS A/WH/CHA/09-BOUND THE SINGLE CHAIN FRAGME ANTIBODY R50
Descriptor: A/WH/CHA/09 VP1, A/WH/CHA/09 VP2, A/WH/CHA/09 VP3, ...
Authors:He, Y, Lou, Z.
Deposit date:2020-09-20
Release date:2021-04-14
Last modified:2021-05-12
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization.
Plos Pathog., 17, 2021
7D3C
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BU of 7d3c by Molmil
The newly emerged SARS-like coronavirus HCoV-EMC also has an "Achilles' heel": current effective inhibitor targeting a 3C-like protease
Descriptor: 3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE
Authors:Yan, L, Ren, Z.
Deposit date:2020-09-18
Release date:2021-11-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The newly emerged SARS-like coronavirus HCoV-EMC also has an "Achilles' heel": current effective inhibitor targeting a 3C-like protease
Protein cell, 4, 2013
7EAN
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BU of 7ean by Molmil
immune complex of SARS-CoV-2 RBD and cross-neutralizing antibody 6D6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SARS-CoV-2 cross-neutralizing mAb 6D6, Light chain of SARS-CoV-2 cross-neutralizing mAb 6D6, ...
Authors:Li, T.T, Gu, Y, Li, S.W.
Deposit date:2021-03-07
Release date:2021-03-31
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants.
Nat Commun, 12, 2021
7FEI
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BU of 7fei by Molmil
Complex of FMDV A/WH/CHA/09 and bovine neutralizing scFv antibody R55
Descriptor: Capsid protein VP0, IG HEAVY CHAIN VARIABLE REGION, IG LAMDA CHAIN VARIABLE REGION
Authors:He, Y, Li, K, Lou, Z.
Deposit date:2021-07-20
Release date:2021-09-29
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.91 Å)
Cite:Structures of Foot-and-Mouth Disease Virus with Bovine Neutralizing Antibodies Reveal the Determinant of Intraserotype Cross-Neutralization.
J.Virol., 95, 2021

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数据于2024-05-29公开中

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