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3JAJ
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BU of 3jaj by Molmil
Structure of the engaged state of the mammalian SRP-ribosome complex
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Voorhees, R.M, Hegde, R.S.
Deposit date:2015-06-16
Release date:2015-08-05
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Structures of the scanning and engaged states of the mammalian SRP-ribosome complex.
Elife, 4, 2015
3JC2
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BU of 3jc2 by Molmil
The structure of the mammalian Sec61 channel opened by a signal sequence
Descriptor: Prolactin, Protein transport protein Sec61 subunit alpha isoform 1, Protein transport protein Sec61 subunit beta, ...
Authors:Voorhees, R.M, Hegde, R.S.
Deposit date:2015-11-15
Release date:2016-01-13
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of the Sec61 channel opened by a signal sequence.
Science, 351, 2016
4V8N
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BU of 4v8n by Molmil
The crystal structure of agmatidine tRNA-Ile2 bound to the 70S ribosome in the A and P site.
Descriptor: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Voorhees, R.M, Mandal, D, Neubauer, C, Koehrer, C, RajBhandary, U.L, Ramakrishnan, V.
Deposit date:2013-02-13
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Structural Basis for Specific Decoding of Aua by Isoleucine tRNA on the Ribosome
Nat.Struct.Mol.Biol., 20, 2013
4V5C
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BU of 4v5c by Molmil
Structure of the Thermus thermophilus 70S ribosome in complex with mRNA, paromomycin, acylated A-site tRNA, deacylated P-site tRNA, and E-site tRNA.
Descriptor: 16S ribosomal RNA, 23S Ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Voorhees, R.M, Weixlbaumer, A, Loakes, D, Kelley, A.C, Ramakrishnan, V.
Deposit date:2009-03-24
Release date:2014-07-09
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Insights Into Substrate Stabilization from Snapshots of the Peptidyl Transferase Center of the Intact 70S Ribosome
Nat.Struct.Mol.Biol., 16, 2009
4V5D
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BU of 4v5d by Molmil
Structure of the Thermus thermophilus 70S ribosome in complex with mRNA, paromomycin, acylated A- and P-site tRNAs, and E-site tRNA.
Descriptor: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Voorhees, R.M, Weixlbaumer, A, Loakes, D, Kelley, A.C, Ramakrishnan, V.
Deposit date:2009-03-24
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome.
Nat. Struct. Mol. Biol., 16, 2009
4V5L
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BU of 4v5l by Molmil
The structure of EF-Tu and aminoacyl-tRNA bound to the 70S ribosome with a GTP analog
Descriptor: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Voorhees, R.M, Schmeing, T.M, Ramakrishnan, V.
Deposit date:2010-09-02
Release date:2014-07-09
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Mechanism for Activation of GTP Hydrolysis on the Ribosome.
Science, 330, 2010
3J7Q
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BU of 3j7q by Molmil
Structure of the idle mammalian ribosome-Sec61 complex
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S.
Deposit date:2014-08-01
Release date:2014-09-03
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
3J7R
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BU of 3j7r by Molmil
Structure of the translating mammalian ribosome-Sec61 complex
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S.
Deposit date:2014-08-01
Release date:2014-09-03
Last modified:2019-10-30
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
3J7O
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BU of 3j7o by Molmil
Structure of the mammalian 60S ribosomal subunit
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S.
Deposit date:2014-08-01
Release date:2014-09-03
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
3JAN
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BU of 3jan by Molmil
Structure of the scanning state of the mammalian SRP-ribosome complex
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Voorhees, R.M, Hegde, R.S.
Deposit date:2015-06-17
Release date:2015-08-05
Last modified:2015-12-30
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Structures of the scanning and engaged states of the mammalian SRP-ribosome complex.
Elife, 4, 2015
3J7P
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BU of 3j7p by Molmil
Structure of the 80S mammalian ribosome bound to eEF2
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S.
Deposit date:2014-08-01
Release date:2014-09-03
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
9C7U
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BU of 9c7u by Molmil
Structure of the human truncated BOS complex in GDN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BOS complex subunit NOMO2, Nicalin, ...
Authors:Nguyen, V.N, Tomaleri, G.P, Voorhees, R.M.
Deposit date:2024-06-11
Release date:2024-08-21
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Role of a holo-insertase complex in the biogenesis of biophysically diverse ER membrane proteins.
Mol.Cell, 84, 2024
9C7V
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BU of 9c7v by Molmil
Structure of the human BOS:human EMC complex in GDN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BOS complex subunit NOMO2, ...
Authors:Nguyen, V.N, Tomaleri, G.P, Voorhees, R.M.
Deposit date:2024-06-11
Release date:2024-08-21
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Role of a holo-insertase complex in the biogenesis of biophysically diverse ER membrane proteins.
Mol.Cell, 84, 2024
4V5Q
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BU of 4v5q by Molmil
The crystal structure of EF-Tu and G24A-tRNA-Trp bound to a near- cognate codon on the 70S ribosome
Descriptor: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V.
Deposit date:2010-12-07
Release date:2014-07-09
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding.
Nat.Struct.Mol.Biol., 18, 2011
6WW7
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BU of 6ww7 by Molmil
Structure of the human ER membrane protein complex in a lipid nanodisc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ER Membrane Protein Complex Subunit 4, ...
Authors:Tomaleri, G.P, Januszyk, K, Pleiner, T, Inglis, A.J, Voorhees, R.M.
Deposit date:2020-05-08
Release date:2020-05-27
Last modified:2020-08-05
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for membrane insertion by the human ER membrane protein complex.
Science, 369, 2020
4V5P
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BU of 4v5p by Molmil
The crystal structure of EF-Tu and A9C-tRNA-Trp bound to a near- cognate codon on the 70S ribosome
Descriptor: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V.
Deposit date:2010-12-07
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding.
Nat.Struct.Mol.Biol., 18, 2011
4V5E
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BU of 4v5e by Molmil
Insights into translational termination from the structure of RF2 bound to the ribosome
Descriptor: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Weixlbaumer, A, Jin, H, Neubauer, C, Voorhees, R.M, Petry, S, Kelley, A.C, Ramakrishnan, V.
Deposit date:2009-04-30
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Insights Into Translational Termination from the Structure of Rf2 Bound to the Ribosome.
Science, 322, 2008
4V5R
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BU of 4v5r by Molmil
The crystal structure of EF-Tu and Trp-tRNA-Trp bound to a cognate codon on the 70S ribosome.
Descriptor: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V.
Deposit date:2010-12-07
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding.
Nat.Struct.Mol.Biol., 18, 2011
4V5S
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BU of 4v5s by Molmil
The crystal structure of EF-Tu and G24A-tRNA-Trp bound to a cognate codon on the 70S ribosome.
Descriptor: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V.
Deposit date:2010-12-07
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding.
Nat.Struct.Mol.Biol., 18, 2011
4V5G
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BU of 4v5g by Molmil
The crystal structure of the 70S ribosome bound to EF-Tu and tRNA
Descriptor: 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V.
Deposit date:2009-09-01
Release date:2014-07-09
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The crystal structure of the ribosome bound to EF-Tu and aminoacyl-tRNA.
Science, 326, 2009
8S9S
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BU of 8s9s by Molmil
Structure of the human ER membrane protein complex (EMC) in GDN
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Tomaleri, G.P, Nguyen, V.N, Voorhees, R.M.
Deposit date:2023-03-30
Release date:2023-05-17
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:A selectivity filter in the ER membrane protein complex limits protein misinsertion at the ER.
J.Cell Biol., 222, 2023

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