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Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:	Gorman, J, Kwong, P.D.
Deposit date:	2019-08-08
Release date:	2019-10-02
Last modified:	2024-10-09
Method:	X-RAY DIFFRACTION (2.301 Å)
Cite:	Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields. Immunity, 51, 2019

1ZWK

Structure of WrbA from Pseudomonas aeruginosa
Descriptor:	PHOSPHATE ION, Trp repressor binding protein WrbA
Authors:	Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:	2005-06-03
Release date:	2005-06-14
Last modified:	2023-08-23
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Crystal structures of the tryptophan repressor binding protein WrbA and complexes with flavin mononucleotide. Protein Sci., 14, 2005

2A1F

Crystal Structure of Uridylate kinase
Descriptor:	Uridylate kinase
Authors:	Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:	2005-06-20
Release date:	2005-06-28
Last modified:	2023-08-23
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Crystal Structure of Uridylate kinase To be Published

2AKO

Crystal structure of Glutamate 5-kinase from Campylobacter jejuni
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, Glutamate 5-kinase
Authors:	Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:	2005-08-03
Release date:	2005-08-09
Last modified:	2024-10-30
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Crystal structure of Glutamate 5-kinase from Campylobacter jejuni To be Published

8T5C

Lassa GPC Trimer in complex with Fab 8.11G and nanobody D5
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 8.11G Heavy Chain, 8.11G Light Chain, ...
Authors:	Gorman, J, Kwong, P.D.
Deposit date:	2023-06-13
Release date:	2024-01-03
Last modified:	2024-01-24
Method:	ELECTRON MICROSCOPY (4.7 Å)
Cite:	Cleavage-intermediate Lassa virus trimer elicits neutralizing responses, identifies neutralizing nanobodies, and reveals an apex-situated site-of-vulnerability. Nat Commun, 15, 2024

8DUA

SIV E660.CR54 SOS-2P Env Trimer with ITS92.02
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, Envelope glycoprotein gp41, ...
Authors:	Gorman, J, Kwong, P.D.
Deposit date:	2022-07-27
Release date:	2022-10-26
Last modified:	2024-10-30
Method:	ELECTRON MICROSCOPY (4.32 Å)
Cite:	Cryo-EM structures of prefusion SIV envelope trimer. Nat.Struct.Mol.Biol., 29, 2022

8DVD

Cryo-EM structure of SIVmac239 SOS-2P Env trimer in complex with human bNAb PGT145
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:	Gorman, J, Kwong, P.D.
Deposit date:	2022-07-28
Release date:	2022-11-16
Last modified:	2022-11-30
Method:	ELECTRON MICROSCOPY (4.12 Å)
Cite:	Cryo-EM structures of prefusion SIV envelope trimer. Nat.Struct.Mol.Biol., 29, 2022

2AWD

Crystal structure of LacC from Enterococcus faecalis
Descriptor:	BROMIDE ION, tagatose-6-phosphate kinase
Authors:	Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:	2005-08-31
Release date:	2005-09-13
Last modified:	2024-10-30
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Crystal structure of LacC from Enterococcus faecalis To be Published

7UR6

Cryo-EM structure of SHIV-elicited, FP-directed Rhesus Fab RM6561.DH1021.14 in complex with stabilized HIV-1 Env Ce1176 DS-SOSIP.664
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain, ...
Authors:	Gorman, J, Kwong, P.D.
Deposit date:	2022-04-21
Release date:	2023-04-26
Last modified:	2024-10-09
Method:	ELECTRON MICROSCOPY (3.46 Å)
Cite:	Cryo-EM structure of SHIV-elicited, FP-directed Rhesus Fab RM6561.DH1021.14 in complex with stabilized HIV-1 Env Ce1176 DS-SOSIP.664 To Be Published

2F02

Crystal Structure of LacC from Enterococcus Faecalis in complex with ATP
Descriptor:	ADENOSINE-5'-TRIPHOSPHATE, tagatose-6-phosphate kinase
Authors:	Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:	2005-11-10
Release date:	2005-11-22
Last modified:	2024-10-30
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Crystal Structure of LacC from Enterococcus Faecalis in complex with ATP To be Published

5ESZ

Crystal Structure of Broadly Neutralizing Antibody CH04, Isolated from Donor CH0219, in Complex with Scaffolded Trimeric HIV-1 Env V1V2 Domain from the Clade AE Strain A244
Descriptor:	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase,Envelope glycoprotein gp160, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH04 Heavy Chain, ...
Authors:	Gorman, J, Yang, M, Kwong, P.D.
Deposit date:	2015-11-17
Release date:	2015-12-16
Last modified:	2024-10-30
Method:	X-RAY DIFFRACTION (4.191 Å)
Cite:	Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design. Nat. Struct. Mol. Biol., 23, 2016

5ESV

Crystal Structure of Broadly Neutralizing Antibody CH03, Isolated from Donor CH0219, in Complex with Scaffolded Trimeric HIV-1 Env V1V2 Domain from the Clade C Superinfecting Strain of Donor CAP256.
Descriptor:	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase,Envelope glycoprotein gp160, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:	Gorman, J, Yang, M, Kwong, P.D.
Deposit date:	2015-11-17
Release date:	2015-12-16
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (3.105 Å)
Cite:	Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design. Nat.Struct.Mol.Biol., 23, 2016

6VRW

Cryo-EM structure of stabilized HIV-1 Env trimer CAP256.wk34.c80 SOSIP.RnS2
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:	Gorman, J, Kwong, P.D.
Deposit date:	2020-02-10
Release date:	2020-03-11
Last modified:	2024-10-09
Method:	ELECTRON MICROSCOPY (3.71 Å)
Cite:	Structure of Super-Potent Antibody CAP256-VRC26.25 in Complex with HIV-1 Envelope Reveals a Combined Mode of Trimer-Apex Recognition. Cell Rep, 31, 2020

6VTT

Cryo-EM Structure of CAP256-VRC26.25 Fab bound to HIV-1 Env trimer CAP256.wk34.c80 SOSIP.RnS2
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:	Gorman, J, Kwong, P.D.
Deposit date:	2020-02-13
Release date:	2020-04-08
Last modified:	2021-10-06
Method:	ELECTRON MICROSCOPY (3.7 Å)
Cite:	Structure of Super-Potent Antibody CAP256-VRC26.25 in Complex with HIV-1 Envelope Reveals a Combined Mode of Trimer-Apex Recognition. Cell Rep, 31, 2020

6VRY

Structure of NCI09 fab in complex with SIV V2 peptide
Descriptor:	NCI09 heavy chain, NCI09 light chain, SIV V2 peptide, ...
Authors:	Gorman, J, Ahmadi, M, Kwong, P.D.
Deposit date:	2020-02-10
Release date:	2020-12-30
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (1.4 Å)
Cite:	HIV vaccine candidate with V1 deletion reveals virus vulnerability to V2 antibodies Iscience, 2020

1YRH

Crystal Structure Of Trp Repressor Binding Protein Wrba in complex with FMN
Descriptor:	FLAVIN MONONUCLEOTIDE, trp repressor binding protein WrbA
Authors:	Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:	2005-02-03
Release date:	2005-02-15
Last modified:	2021-02-03
Method:	X-RAY DIFFRACTION (3.11 Å)
Cite:	Crystal structures of the tryptophan repressor binding protein WrbA and complexes with flavin mononucleotide. Protein Sci., 14, 2005

1YDG

Crystal Structure of Trp repressor binding protein WrbA
Descriptor:	SULFATE ION, trp repressor binding protein WrbA
Authors:	Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:	2004-12-23
Release date:	2005-01-04
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Crystal structures of the tryptophan repressor binding protein WrbA and complexes with flavin mononucleotide. Protein Sci., 14, 2005

1Y65

Crystal structure of beta-hexosaminidase from Vibrio cholerae in complex with N-acetyl-D-glucosamine to a resolution of 1.85
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-hexosaminidase
Authors:	Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:	2004-12-03
Release date:	2004-12-14
Last modified:	2023-08-23
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Crystal structure of beta-hexosaminidase from Vibrio cholerae in complex with N-acetyl-D-glucosamine to a resolution of 1.85 To be Published

1ZWL

Structure of WrbA from Pseudomonas aeruginosa in complex with FMN
Descriptor:	FLAVIN MONONUCLEOTIDE, Trp repressor binding protein WrbA
Authors:	Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:	2005-06-03
Release date:	2005-06-14
Last modified:	2023-08-23
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Crystal structures of the tryptophan repressor binding protein WrbA and complexes with flavin mononucleotide. Protein Sci., 14, 2005

1TR9

Structure of beta-hexosaminidase from Vibrio cholerae
Descriptor:	Beta-hexosaminidase
Authors:	Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:	2004-06-21
Release date:	2004-12-14
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Structure of beta-hexosaminidase from Vibrio cholerae To be Published

1R3D

Crystal structure of protein VC1974 from Vibrio cholerae, Pfam abhydrolase
Descriptor:	conserved hypothetical protein VC1974
Authors:	Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:	2003-10-01
Release date:	2004-11-30
Last modified:	2024-10-30
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Structural Genomics target NYSGRC-T920 related to A/B hydrolase fold. To be Published

1TVL

Structure of YTNJ from Bacillus subtilis
Descriptor:	protein YTNJ
Authors:	Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:	2004-06-29
Release date:	2004-07-13
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (2.104 Å)
Cite:	Structure of YTNJ from Bacillus subtilis To be Published

1TO3

Structure of yiht from Salmonella typhimurium
Descriptor:	BROMIDE ION, PHOSPHATE ION, Putative aldolase yihT
Authors:	Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:	2004-06-11
Release date:	2004-06-22
Last modified:	2024-10-30
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	Structure of yiht from Salmonella typhimurium To be Published

1S80

Structure of Serine Acetyltransferase from Haemophilis influenzae Rd
Descriptor:	Serine acetyltransferase
Authors:	Gorman, J, Gogos, A, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:	2004-01-30
Release date:	2004-08-31
Last modified:	2024-10-30
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	Structure of serine acetyltransferase from Haemophilus influenzae Rd. Acta Crystallogr.,Sect.D, 60, 2004

7LPN

Cryo-EM structure of llama J3 VHH antibody in complex with HIV-1 Env BG505 DS-SOSIP.664
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:	Gorman, J, Kwong, P.D.
Deposit date:	2021-02-12
Release date:	2022-02-23
Last modified:	2023-03-29
Method:	ELECTRON MICROSCOPY (3.61 Å)
Cite:	Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site. Structure, 30, 2022

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