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4A3N
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BU of 4a3n by Molmil
Crystal Structure of HMG-BOX of Human SOX17
Descriptor: TRANSCRIPTION FACTOR SOX-17, ZINC ION
Authors:Gao, N, Gao, H, Qian, H, Si, S, Xie, Y.
Deposit date:2011-10-01
Release date:2011-12-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis of Human Transcription Factor Sry-Related Box 17 Binding to DNA.
Protein Pept.Lett., 20, 2013
5DI1
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BU of 5di1 by Molmil
MAP4K4 in complex with an inhibitor
Descriptor: 4-{6-amino-5-[4-(methylsulfonyl)phenyl]pyridin-3-yl}phenol, Mitogen-activated protein kinase kinase kinase kinase 4
Authors:Liu, S.
Deposit date:2015-08-31
Release date:2016-01-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Discovery of an in Vivo Tool to Establish Proof-of-Concept for MAP4K4-Based Antidiabetic Treatment.
Acs Med.Chem.Lett., 6, 2015
6IIO
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BU of 6iio by Molmil
Cryo-EM structure of CV-A10 native empty particle
Descriptor: VP0, VP1, VP3
Authors:Chen, J.H, Ye, X.H, Cong, Y, Huang, Z.
Deposit date:2018-10-07
Release date:2018-11-07
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Coxsackievirus A10 atomic structure facilitating the discovery of a broad-spectrum inhibitor against human enteroviruses.
Cell Discov, 5, 2019
1MJC
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BU of 1mjc by Molmil
CRYSTAL STRUCTURE OF CSPA, THE MAJOR COLD SHOCK PROTEIN OF ESCHERICHIA COLI
Descriptor: MAJOR COLD-SHOCK PROTEIN 7.4
Authors:Schindelin, H, Heinemann, U.
Deposit date:1994-03-18
Release date:1994-06-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of CspA, the major cold shock protein of Escherichia coli.
Proc.Natl.Acad.Sci.USA, 91, 1994
7MKF
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BU of 7mkf by Molmil
Paired helical tau filament extracted from PrP-CAA Patient brain tissue | tau filament | PHF Tau
Descriptor: Isoform Tau-F of Microtubule-associated protein tau
Authors:Hoq, M.R.
Deposit date:2021-04-23
Release date:2021-07-28
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of Tau filaments in Prion protein amyloidoses.
Acta Neuropathol, 142, 2021
7MKG
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BU of 7mkg by Molmil
Straight tau filament extracted from PrP-CAA Patient brain tissue | tau filament | SF Tau
Descriptor: Isoform Tau-F of Microtubule-associated protein tau
Authors:Hoq, M.R.
Deposit date:2021-04-23
Release date:2021-07-28
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Structure of Tau filaments in Prion protein amyloidoses.
Acta Neuropathol, 142, 2021
7MKH
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BU of 7mkh by Molmil
Paired helical tau filament extracted from GSS Patient brain tissue | tau filament from Gerstmann Straussler Scheinker disease | PHF Tau
Descriptor: Isoform Tau-F of Microtubule-associated protein tau
Authors:Hoq, M.R.
Deposit date:2021-04-23
Release date:2021-07-28
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of Tau filaments in Prion protein amyloidoses.
Acta Neuropathol, 142, 2021
6EDZ
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BU of 6edz by Molmil
Crystal structure of Mycobacterium tuberculosis ICL2 in complex with acetyl-CoA, form I
Descriptor: ACETYL COENZYME *A, Isocitrate lyase 2
Authors:Bashiri, G, Bhusal, R, Leung, I.
Deposit date:2018-08-12
Release date:2019-08-14
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2.
Nat Commun, 10, 2019
6EAZ
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BU of 6eaz by Molmil
Apo structure of the mitochondrial calcium uniporter protein MICU2
Descriptor: Calcium uptake protein 2, mitochondrial, GLYCEROL
Authors:Kamer, K.J, Grabarek, Z.
Deposit date:2018-08-03
Release date:2019-02-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.504 Å)
Cite:Crystal structure of MICU2 and comparison with MICU1 reveal insights into the uniporter gating mechanism.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6EDW
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BU of 6edw by Molmil
Crystal structure of Mycobacterium tuberculosis ICL2 in the apo form
Descriptor: GLYCEROL, Isocitrate lyase 2, MAGNESIUM ION
Authors:Bashiri, G, Bhusal, R, Leung, I.
Deposit date:2018-08-12
Release date:2019-08-14
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2.
Nat Commun, 10, 2019
3S7S
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BU of 3s7s by Molmil
Crystal structure of human placental aromatase complexed with breast cancer drug exemestane
Descriptor: (8alpha,10alpha,13alpha)-6-methylideneandrosta-1,4-diene-3,17-dione, Cytochrome P450 19A1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Ghosh, D.
Deposit date:2011-05-26
Release date:2012-06-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Novel aromatase inhibitors by structure-guided design.
J.Med.Chem., 55, 2012
3S79
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BU of 3s79 by Molmil
Human placental aromatase cytochrome P450 (CYP19A1) refined at 2.75 angstrom
Descriptor: 4-ANDROSTENE-3-17-DIONE, Cytochrome P450 19A1, PHOSPHATE ION, ...
Authors:Ghosh, D.
Deposit date:2011-05-26
Release date:2012-06-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Novel aromatase inhibitors by structure-guided design.
J.Med.Chem., 55, 2012
3N1Z
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BU of 3n1z by Molmil
X-ray Crystal Structure of Toluene/o-Xylene Monooxygenase Hydroxylase T201S Mutant
Descriptor: FE (III) ION, GLYCEROL, HEXAETHYLENE GLYCOL, ...
Authors:McCormick, M.S, Sazinsky, M.H, Lippard, S.J.
Deposit date:2010-05-17
Release date:2010-10-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Active Site Threonine Facilitates Proton Transfer during Dioxygen Activation at the Diiron Center of Toluene/o-Xylene Monooxygenase Hydroxylase.
J.Am.Chem.Soc., 132, 2010
3N20
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BU of 3n20 by Molmil
X-ray Crystal Structure of Toluene/o-Xylene Monooxygenase Hydroxylase T201V Mutant
Descriptor: FE (III) ION, GLYCEROL, HEXAETHYLENE GLYCOL, ...
Authors:McCormick, M.S, Sazinsky, M.H, Lippard, S.J.
Deposit date:2010-05-17
Release date:2010-10-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Active Site Threonine Facilitates Proton Transfer during Dioxygen Activation at the Diiron Center of Toluene/o-Xylene Monooxygenase Hydroxylase.
J.Am.Chem.Soc., 132, 2010
3N1X
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BU of 3n1x by Molmil
X-ray Crystal Structure of Toluene/o-Xylene Monooxygenase Hydroxylase T201C Mutant
Descriptor: 1,2-ETHANEDIOL, FE (III) ION, HYDROXIDE ION, ...
Authors:Sazinsky, M.H, McCormick, M.S, Lippard, S.J.
Deposit date:2010-05-17
Release date:2010-10-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Active Site Threonine Facilitates Proton Transfer during Dioxygen Activation at the Diiron Center of Toluene/o-Xylene Monooxygenase Hydroxylase.
J.Am.Chem.Soc., 132, 2010
3N1Y
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BU of 3n1y by Molmil
X-ray Crystal Structure of Toluene/o-Xylene Monooxygenase Hydroxylase T201G Mutant
Descriptor: FE (III) ION, GLYCEROL, HEXAETHYLENE GLYCOL, ...
Authors:McCormick, M.S, Sazinsky, M.H, Lippard, S.J.
Deposit date:2010-05-17
Release date:2010-10-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Active Site Threonine Facilitates Proton Transfer during Dioxygen Activation at the Diiron Center of Toluene/o-Xylene Monooxygenase Hydroxylase.
J.Am.Chem.Soc., 132, 2010
5W3M
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BU of 5w3m by Molmil
CryoEM structure of rhinovirus B14 in complex with C5 Fab (33 degrees Celsius, molar ratio 1:1, full particle)
Descriptor: C5 antibody variable heavy domain, C5 antibody variable light domain, viral protein 1, ...
Authors:Liu, Y, Dong, Y, Rossmann, M.G.
Deposit date:2017-06-08
Release date:2017-07-12
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (2.26 Å)
Cite:Antibody-induced uncoating of human rhinovirus B14.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5VEB
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BU of 5veb by Molmil
Crystal structure of a Fab binding to extracellular domain 5 of Cadherin-6
Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose, Cadherin-6, anti-CDH6 Fab heavy chain, ...
Authors:Zhu, X, Bialucha, C.U, London, A, Clark, K, Hu, T.
Deposit date:2017-04-04
Release date:2017-06-07
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Discovery and Optimization of HKT288, a Cadherin-6-Targeting ADC for the Treatment of Ovarian and Renal Cancers.
Cancer Discov, 7, 2017
4NGA
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BU of 4nga by Molmil
Factor viia in complex with the inhibitor (2R)-2-[(1-aminoisoquinolin-6-yl)amino]-2-[3-ethoxy-4-(propan-2-yloxy)phenyl]-N-[2-(propan-2-ylsulfonyl)benzyl]ethanamide
Descriptor: (2R)-2-[(1-aminoisoquinolin-6-yl)amino]-2-[3-ethoxy-4-(propan-2-yloxy)phenyl]-N-[2-(propan-2-ylsulfonyl)benzyl]ethanamide, CALCIUM ION, Factor VIIa (Heavy Chain), ...
Authors:Wei, A, Anumula, R.
Deposit date:2013-11-01
Release date:2014-01-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Design and Synthesis of Phenylpyrrolidine Phenylglycinamides As Highly Potent and Selective TF-FVIIa Inhibitors.
ACS Med Chem Lett, 5, 2014
4OV5
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BU of 4ov5 by Molmil
Structure of HLA-DR1 with a bound peptide with non-optimal alanine in the P1 pocket
Descriptor: HLA class I histocompatibility antigen, A-2 alpha chain, HLA class II histocompatibility antigen, ...
Authors:Trenh, P, Yin, L, Stern, L.J.
Deposit date:2014-02-20
Release date:2014-07-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Susceptibility to HLA-DM Protein Is Determined by a Dynamic Conformation of Major Histocompatibility Complex Class II Molecule Bound with Peptide.
J.Biol.Chem., 289, 2014
5W3O
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BU of 5w3o by Molmil
CryoEM structure of rhinovirus B14 in complex with C5 Fab (33 degrees Celsius, molar ratio 1:3, empty particle)
Descriptor: C5 antibody variable heavy domain, C5 antibody variable light domain, viral protein 1, ...
Authors:Liu, Y, Dong, Y, Rossmann, M.G.
Deposit date:2017-06-08
Release date:2017-07-12
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Antibody-induced uncoating of human rhinovirus B14.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W3L
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BU of 5w3l by Molmil
CryoEM structure of rhinovirus B14 in complex with C5 Fab (4 degrees Celsius, molar ratio 1:3, full particle)
Descriptor: C5 antibody variable heavy domain, C5 antibody variable light domain, viral protein 1, ...
Authors:Liu, Y, Dong, Y, Rossmann, M.G.
Deposit date:2017-06-08
Release date:2017-07-12
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (2.71 Å)
Cite:Antibody-induced uncoating of human rhinovirus B14.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4GL5
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BU of 4gl5 by Molmil
Structure of human placental aromatase complexed with designed inhibitor HDDG029 (compound 4)
Descriptor: (6alpha,8alpha)-6-(but-2-yn-1-yloxy)androsta-1,4-diene-3,17-dione, Cytochrome P450 19A1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Ghosh, D.
Deposit date:2012-08-13
Release date:2012-09-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.48 Å)
Cite:Novel aromatase inhibitors by structure-guided design.
J.Med.Chem., 55, 2012
5W3E
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BU of 5w3e by Molmil
CryoEM structure of rhinovirus B14 in complex with C5 Fab (33 degrees Celsius, molar ratio 1:3, full particle)
Descriptor: C5 antibody variable heavy domain, C5 antibody variable light domain, viral protein 1, ...
Authors:Liu, Y, Dong, Y, Rossmann, M.G.
Deposit date:2017-06-07
Release date:2017-07-12
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (2.53 Å)
Cite:Antibody-induced uncoating of human rhinovirus B14.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4PL6
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BU of 4pl6 by Molmil
Structure of the chromodomain of MRG2 in complex with H3K4me3
Descriptor: At1g02740, H3K4me3
Authors:Liu, Y.C, Huang, Y.
Deposit date:2014-05-16
Release date:2015-07-22
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.681 Å)
Cite:Regulation of arabidopsis flowering by the histone mark readers MRG1/2 via interaction with CONSTANS to modulate FT expression.
Plos Genet., 10, 2014

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