6EDZ

Crystal structure of Mycobacterium tuberculosis ICL2 in complex with acetyl-CoA, form I

Summary for 6EDZ

Related6EDW 6EE1
DescriptorIsocitrate lyase 2, ACETYL COENZYME *A (3 entities in total)
Functional Keywordslyase
Biological sourceMycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Total number of polymer chains4
Total molecular weight353702.19
Authors
Bashiri, G.,Bhusal, R.,Leung, I. (deposition date: 2018-08-12, release date: 2019-08-14)
Primary citation
Bhusal, R.P.,Jiao, W.,Swartjes, A.,Kwai, B.X.C.,Patel, K.,Reynisson, J.,Sperry, J.,Bashiri, G.,Leung, I.K.H.
Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.67 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.24630 3.5% 0.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution