Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004451 | molecular_function | isocitrate lyase activity |
| A | 0006097 | biological_process | glyoxylate cycle |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019752 | biological_process | carboxylic acid metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004451 | molecular_function | isocitrate lyase activity |
| B | 0006097 | biological_process | glyoxylate cycle |
| B | 0006099 | biological_process | tricarboxylic acid cycle |
| B | 0016829 | molecular_function | lyase activity |
| B | 0019752 | biological_process | carboxylic acid metabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004451 | molecular_function | isocitrate lyase activity |
| C | 0006097 | biological_process | glyoxylate cycle |
| C | 0006099 | biological_process | tricarboxylic acid cycle |
| C | 0016829 | molecular_function | lyase activity |
| C | 0019752 | biological_process | carboxylic acid metabolic process |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004451 | molecular_function | isocitrate lyase activity |
| D | 0006097 | biological_process | glyoxylate cycle |
| D | 0006099 | biological_process | tricarboxylic acid cycle |
| D | 0016829 | molecular_function | lyase activity |
| D | 0019752 | biological_process | carboxylic acid metabolic process |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | binding site for residue ACO A 801 |
| Chain | Residue |
| A | GLN676 |
| A | VAL708 |
| A | THR709 |
| A | PRO710 |
| A | THR711 |
| A | ASP713 |
| A | ASN714 |
| A | TYR716 |
| A | GLN717 |
| A | LYS720 |
| A | HIS724 |
| A | ASN677 |
| A | LYS764 |
| A | HOH909 |
| C | ARG665 |
| A | THR678 |
| A | ARG684 |
| A | GLN685 |
| A | LYS686 |
| A | ARG687 |
| A | MET689 |
| A | THR690 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | binding site for residue ACO B 801 |
| Chain | Residue |
| B | VAL673 |
| B | GLN676 |
| B | ASN677 |
| B | THR678 |
| B | ARG684 |
| B | GLN685 |
| B | LYS686 |
| B | ARG687 |
| B | MET689 |
| B | THR690 |
| B | VAL708 |
| B | THR711 |
| B | ASP713 |
| B | ASN714 |
| B | TYR716 |
| B | GLN717 |
| B | LYS720 |
| B | HIS724 |
| B | LYS764 |
| site_id | AC3 |
| Number of Residues | 20 |
| Details | binding site for residue ACO C 801 |
| Chain | Residue |
| C | ARG674 |
| C | ASP675 |
| C | GLN676 |
| C | ASN677 |
| C | THR678 |
| C | ARG684 |
| C | GLN685 |
| C | LYS686 |
| C | ARG687 |
| C | MET689 |
| C | THR690 |
| C | VAL708 |
| C | THR711 |
| C | ASP713 |
| C | ASN714 |
| C | TYR716 |
| C | GLN717 |
| C | LYS720 |
| C | HIS724 |
| D | TYR716 |
| site_id | AC4 |
| Number of Residues | 24 |
| Details | binding site for residue ACO D 801 |
| Chain | Residue |
| B | ARG665 |
| D | VAL673 |
| D | GLN676 |
| D | ASN677 |
| D | THR678 |
| D | ARG684 |
| D | GLN685 |
| D | LYS686 |
| D | ARG687 |
| D | MET689 |
| D | THR690 |
| D | VAL708 |
| D | THR709 |
| D | PRO710 |
| D | THR711 |
| D | ASP713 |
| D | ASN714 |
| D | TYR716 |
| D | GLN717 |
| D | LYS720 |
| D | HIS724 |
| D | LYS764 |
| D | HOH907 |
| D | HOH942 |
Functional Information from PROSITE/UniProt
| site_id | PS00161 |
| Number of Residues | 6 |
| Details | ISOCITRATE_LYASE Isocitrate lyase signature. KKCGHQ |
| Chain | Residue | Details |
| A | LYS213-GLN218 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"P9WKK7","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 40 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P9WKK7","evidenceCode":"ECO:0000250"}]} |
