7MKH

Paired helical tau filament extracted from GSS Patient brain tissue | tau filament from Gerstmann Straussler Scheinker disease | PHF Tau

Summary for 7MKH

• Entry DOI: 10.2210/pdb7mkh/pdb
• EMDB information: 23894
• Descriptor: Isoform Tau-F of Microtubule-associated protein tau (1 entity in total)
• Functional Keywords: tau filament, gss, prp-caa, amyloid fibril, alzheimer disease, protein fibril
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 10
• Total formula weight: 459198.71

Authors

Hoq, M.R. (deposition date: 2021-04-23, release date: 2021-07-28, Last modification date: 2022-02-16)

• Primary citation: Hallinan, G.I.,Hoq, M.R.,Ghosh, M.,Vago, F.S.,Fernandez, A.,Garringer, H.J.,Vidal, R.,Jiang, W.,Ghetti, B.; Structure of Tau filaments in Prion protein amyloidoses.; Acta Neuropathol, 142:227-241, 2021; PubMed: 34128081; DOI: 10.1007/s00401-021-02336-w

Experimental method

ELECTRON MICROSCOPY (3.3 Å)