6EDW

Crystal structure of Mycobacterium tuberculosis ICL2 in the apo form

Summary for 6EDW

Related6EDZ 6EE1
DescriptorIsocitrate lyase 2, GLYCEROL, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordslyase
Biological sourceMycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Total number of polymer chains4
Total molecular weight351094.51
Authors
Bashiri, G.,Bhusal, R.,Leung, I. (deposition date: 2018-08-12, release date: 2019-08-14, Last modification date: 2019-10-23)
Primary citation
Bhusal, R.P.,Jiao, W.,Kwai, B.X.C.,Reynisson, J.,Collins, A.J.,Sperry, J.,Bashiri, G.,Leung, I.K.H.
Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2.
Nat Commun, 10:4639-4639, 2019
PubMed: 31604954 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-019-12614-7
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.21220 0.9% 4.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report