6EDW

Crystal structure of Mycobacterium tuberculosis ICL2 in the apo form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Isocitrate lyase 2	polymer	786	87616.0	4	UniProt (Q8VJU4) Pfam (PF00463)	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	ICL2,Isocitrase,Isocitratase
2	E, F, J, K, N (A, C, D)	GLYCEROL	non-polymer		92.1	5	Chemie (GOL)
3	G, H, I, L, M... (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	7	Chemie (MG)
4	Q, R, S, T (A, B, C, D)	water	water		18.0	3468	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 766 (UniProt: Q8VJU4)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	350463.9
Non-Polymers*	Number of molecules	12
	Total formula weight	630.6
All*	Total formula weight	351094.5

*Water molecules are not included.