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3S79

Human placental aromatase cytochrome P450 (CYP19A1) refined at 2.75 angstrom

Summary for 3S79
Entry DOI10.2210/pdb3s79/pdb
Related3S7S
DescriptorCytochrome P450 19A1, PROTOPORPHYRIN IX CONTAINING FE, 4-ANDROSTENE-3-17-DIONE, ... (5 entities in total)
Functional Keywordsoxidoreductase
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Peripheral membrane protein: P11511
Total number of polymer chains1
Total formula weight59142.67
Authors
Ghosh, D. (deposition date: 2011-05-26, release date: 2012-06-06, Last modification date: 2023-09-13)
Primary citationGhosh, D.,Lo, J.,Morton, D.,Valette, D.,Xi, J.,Griswold, J.,Hubbell, S.,Egbuta, C.,Jiang, W.,An, J.,Davies, H.M.
Novel aromatase inhibitors by structure-guided design.
J.Med.Chem., 55:8464-8476, 2012
Cited by
PubMed: 22951074
DOI: 10.1021/jm300930n
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.75 Å)
Structure validation

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