5YJG
 
 | | Structural insights into periostin functions | | Descriptor: | CALCIUM ION, CHLORIDE ION, CYSTEINE, ... | | Authors: | Liu, H, Liu, J, Xu, F. | | Deposit date: | 2017-10-10 | | Release date: | 2018-05-23 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.399 Å) | | Cite: | Structural characterizations of human periostin dimerization and cysteinylation.
FEBS Lett., 592, 2018
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7LKY
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4B7Q
 | | H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NEURAMINIDASE, ... | | Authors: | Liu, J, van der Vries, E, Vachieri, S.G, Xiong, X, Collins, P.J, Walker, P.A, Haire, L.F, Hay, A.J, Schutten, M, Osterhaus, A.D.M.E, Martin, S.R, Boucher, C.A.B, Skehel, J.J, Gamblin, S.J. | | Deposit date: | 2012-08-21 | | Release date: | 2012-10-03 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.728 Å) | | Cite: | H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis
Plos Pathog., 8, 2012
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4B7R
 | | H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis | | Descriptor: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Liu, J, van der Vries, E, Vachieri, S.G, Xiong, X, Collins, P.J, Walker, P.A, Haire, L.F, Hay, A.J, Schutten, M, Osterhaus, A.D.M.E, Martin, S.R, Boucher, C.A.B, Skehel, J.J, Gamblin, S.J. | | Deposit date: | 2012-08-21 | | Release date: | 2012-10-03 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis
Plos Pathog., 8, 2012
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4CQZ
 | | Crystal Structure of H5 (VN1194) Gln196Arg Mutant Haemagglutinin | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Liu, J, Xiong, X, Xiao, H, Martin, S.R, Coombs, P.J, Collins, P.J, Vachieri, S.G, Walker, P.A, Lin, Y.P, McCauley, J.W, Gamblin, S.J, Skehel, J.J. | | Deposit date: | 2014-02-21 | | Release date: | 2014-05-28 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Enhanced Human Receptor Binding by H5 Haemagglutinins.
Virology, 456, 2014
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3CRP
 | | A heterospecific leucine zipper tetramer | | Descriptor: | GCN4 leucine zipper, SODIUM ION | | Authors: | Liu, J. | | Deposit date: | 2008-04-07 | | Release date: | 2008-10-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | A heterospecific leucine zipper tetramer.
Chem.Biol., 15, 2008
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5HXL
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3DNL
 | | Molecular structure for the HIV-1 gp120 trimer in the b12-bound state | | Descriptor: | HIV-1 envelope glycoprotein gp120 | | Authors: | Borgnia, M.J, Liu, J, Bartesaghi, A, Sapiro, G, Subramaniam, S. | | Deposit date: | 2008-07-02 | | Release date: | 2008-08-19 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (20 Å) | | Cite: | Molecular architecture of native HIV-1 gp120 trimers.
Nature, 455, 2008
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5HYC
 | | Structure based function annotation of a hypothetical protein MGG_01005 related to the development of rice blast fungus | | Descriptor: | Cytoplasmic dynein 1 intermediate chain 2, Uncharacterized protein | | Authors: | Liu, J, Li, G, Huang, J, Peng, Y.-l. | | Deposit date: | 2016-02-01 | | Release date: | 2017-02-01 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure based function-annotation of hypothetical protein MGG_01005 from Magnaporthe oryzae reveals it is the dynein light chain orthologue of dynlt1/3.
Sci Rep, 8, 2018
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3CK4
 | | A heterospecific leucine zipper tetramer | | Descriptor: | GCN4 leucine zipper, MAGNESIUM ION | | Authors: | Liu, J. | | Deposit date: | 2008-03-14 | | Release date: | 2008-10-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | A heterospecific leucine zipper tetramer.
Chem.Biol., 15, 2008
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3DNO
 | | Molecular structure for the HIV-1 gp120 trimer in the CD4-bound state | | Descriptor: | HIV-1 envelope glycoprotein gp120 | | Authors: | Borgnia, M.J, Liu, J, Bartesaghi, A, Sapiro, G, Subramaniam, S. | | Deposit date: | 2008-07-02 | | Release date: | 2008-08-19 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (20 Å) | | Cite: | Molecular architecture of native HIV-1 gp120 trimers.
Nature, 455, 2008
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3DNN
 | | Molecular structure for the HIV-1 gp120 trimer in the unliganded state | | Descriptor: | HIV-1 envelope glycoprotein gp120 | | Authors: | Borgnia, M.J, Liu, J, Bartesaghi, A, Sapiro, G, Subramaniam, S. | | Deposit date: | 2008-07-02 | | Release date: | 2008-08-19 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (20 Å) | | Cite: | Molecular architecture of native HIV-1 gp120 trimers.
Nature, 455, 2008
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8J5D
 | | Cryo-EM structure of starch degradation complex of BAM1-LSF1-MDH | | Descriptor: | Beta-amylase 1, chloroplastic, Malate dehydrogenase, ... | | Authors: | Guan, Z.Y, Liu, J, Yan, J.J. | | Deposit date: | 2023-04-21 | | Release date: | 2024-01-10 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | The LIKE SEX FOUR 1-malate dehydrogenase complex functions as a scaffold to recruit beta-amylase to promote starch degradation.
Plant Cell, 36, 2023
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6NE8
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8TIB
 | | Cryo-EM of tri-pilus from S. islandicus REY15A | | Descriptor: | DUF973 family protein | | Authors: | Eastep, G.N, Liu, J, Rich-New, S.T, Egelman, E.H, Krupovic, M, Wang, F. | | Deposit date: | 2023-07-19 | | Release date: | 2024-01-10 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.47 Å) | | Cite: | Two distinct archaeal type IV pili structures formed by proteins with identical sequence.
Nat Commun, 15, 2024
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8TIF
 | | Cryo-EM of mono-pilus from S. islandicus REY15A | | Descriptor: | DUF973 family protein | | Authors: | Eastep, G.N, Liu, J, Rich-New, S.T, Egelman, E.H, Krupovic, M, Wang, F. | | Deposit date: | 2023-07-19 | | Release date: | 2024-01-10 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.89 Å) | | Cite: | Two distinct archaeal type IV pili structures formed by proteins with identical sequence.
Nat Commun, 15, 2024
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4IDT
 | | Crystal Structure of NIK with 11-bromo-5,6,7,8-tetrahydropyrimido[4',5':3,4]cyclohepta[1,2-b]indol-2-amine (T28) | | Descriptor: | 11-bromo-5,6,7,8-tetrahydropyrimido[4',5':3,4]cyclohepta[1,2-b]indol-2-amine, Mitogen-activated protein kinase kinase kinase 14 | | Authors: | Liu, J, Sudom, A, Wang, Z. | | Deposit date: | 2012-12-13 | | Release date: | 2013-04-17 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Inhibiting NF-KB-inducing kinase (NIK): Discovery, structure-based design, synthesis, structure activity relationship, and co-crystal structures
Bioorg.Med.Chem.Lett., 23, 2013
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4IDV
 | | Crystal Structure of NIK with compound 4-{3-[2-amino-5-(2-methoxyethoxy)pyrimidin-4-yl]-1H-indol-5-yl}-2-methylbut-3-yn-2-ol (13V) | | Descriptor: | 4-{3-[2-amino-5-(2-methoxyethoxy)pyrimidin-4-yl]-1H-indol-5-yl}-2-methylbut-3-yn-2-ol, Mitogen-activated protein kinase kinase kinase 14 | | Authors: | Liu, J, Sudom, A, Wang, Z. | | Deposit date: | 2012-12-13 | | Release date: | 2013-04-17 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Inhibiting NF-KB-inducing kinase (NIK): Discovery, structure-based design, synthesis, structure activity relationship, and co-crystal structures
Bioorg.Med.Chem.Lett., 23, 2013
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3R00
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3R01
 | | The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors | | Descriptor: | 5-bromo-7-methoxy-1-benzofuran-2-carboxylic acid, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase pim-1 | | Authors: | Liu, J. | | Deposit date: | 2011-03-07 | | Release date: | 2011-05-11 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors.
Bioorg.Med.Chem.Lett., 21, 2011
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5GP7
 | | Structural basis for the binding between Tankyrase-1 and USP25 | | Descriptor: | GLYCEROL, Tankyrase-1, Ubiquitin carboxyl-terminal hydrolase 25 | | Authors: | Liu, J, Xu, D, Fu, T, Pan, L. | | Deposit date: | 2016-08-01 | | Release date: | 2017-07-12 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.502 Å) | | Cite: | USP25 regulates Wnt signaling by controlling the stability of tankyrases
Genes Dev., 31, 2017
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2IEQ
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6CI0
 | | Catalytic core subunits (I and II) of cytochrome C oxidase from Rhodobacter sphaeroides with E101A (II) mutation | | Descriptor: | (2S,3R)-heptane-1,2,3-triol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, ... | | Authors: | Liu, J, Hiser, C, Ferguson-Miller, S. | | Deposit date: | 2018-02-23 | | Release date: | 2018-04-25 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The K-path entrance in cytochrome c oxidase is defined by mutation of E101 and controlled by an adjacent ligand binding domain.
Biochim. Biophys. Acta, 1859, 2018
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2LSJ
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2LSG
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