5WVE
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![BU of 5wve by Molmil](/molmil-images/mine/5wve) | Apaf-1-Caspase-9 holoenzyme | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Apoptotic protease-activating factor 1, Caspase, ... | Authors: | Li, Y, Zhou, M, Hu, Q, Shi, Y. | Deposit date: | 2016-12-24 | Release date: | 2017-02-08 | Last modified: | 2017-03-01 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Mechanistic insights into caspase-9 activation by the structure of the apoptosome holoenzyme Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6N1H
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![BU of 6n1h by Molmil](/molmil-images/mine/6n1h) | Cryo-EM structure of ASC-CARD filament | Descriptor: | Apoptosis-associated speck-like protein containing a CARD | Authors: | Li, Y, Fu, T, Wu, H. | Deposit date: | 2018-11-08 | Release date: | 2018-12-05 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.17 Å) | Cite: | Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6N1I
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![BU of 6n1i by Molmil](/molmil-images/mine/6n1i) | Cryo-EM structure of NLRC4-CARD filament | Descriptor: | NLR family CARD domain-containing protein 4 | Authors: | Li, Y, Fu, T, Wu, H. | Deposit date: | 2018-11-08 | Release date: | 2018-12-05 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.58 Å) | Cite: | Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6IMQ
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![BU of 6imq by Molmil](/molmil-images/mine/6imq) | Crystal structure of PML B1-box multimers | Descriptor: | CHLORIDE ION, Protein PML, ZINC ION | Authors: | Li, Y, Ma, X, Chen, Z, Wu, H, Wang, P, Wu, W, Cheng, N, Zeng, L, Zhang, H, Cai, X, Chen, S.J, Chen, Z, Meng, G. | Deposit date: | 2018-10-23 | Release date: | 2019-07-31 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | B1 oligomerization regulates PML nuclear body biogenesis and leukemogenesis. Nat Commun, 10, 2019
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6IUS
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![BU of 6ius by Molmil](/molmil-images/mine/6ius) | A higher kcat Rubisco | Descriptor: | Ribulose-1,5-bisphosphate carboxylase/oxygenase | Authors: | Li, Y, Cai, Z. | Deposit date: | 2018-11-30 | Release date: | 2019-12-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | A higher kcat Rubisco To Be Published
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8JNS
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![BU of 8jns by Molmil](/molmil-images/mine/8jns) | cryo-EM structure of a CED-4 hexamer | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cell death protein 4, MAGNESIUM ION | Authors: | Li, Y, Shi, Y. | Deposit date: | 2023-06-06 | Release date: | 2023-06-28 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural insights into CED-3 activation. Life Sci Alliance, 6, 2023
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8JO0
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![BU of 8jo0 by Molmil](/molmil-images/mine/8jo0) | |
6H8Q
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![BU of 6h8q by Molmil](/molmil-images/mine/6h8q) | Structural basis for Scc3-dependent cohesin recruitment to chromatin | Descriptor: | Cohesin subunit SCC3, DNA (5'-D(P*CP*TP*TP*TP*CP*GP*TP*TP*TP*CP*CP*TP*TP*GP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*CP*AP*AP*GP*GP*AP*AP*AP*CP*GP*AP*AP*AP*G)-3'), ... | Authors: | Li, Y, Muir, K, Panne, D. | Deposit date: | 2018-08-03 | Release date: | 2018-08-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.631 Å) | Cite: | Structural basis for Scc3-dependent cohesin recruitment to chromatin. Elife, 7, 2018
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7WN8
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![BU of 7wn8 by Molmil](/molmil-images/mine/7wn8) | Crystal structure of antibody (BC31M5) binds to CD47 | Descriptor: | BC31M5 Fab Heavy chain, BC31M5 Fab Light chain, Leukocyte surface antigen CD47, ... | Authors: | Li, Y, Wang, W, Sui, J, Zhang, S. | Deposit date: | 2022-01-17 | Release date: | 2023-01-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A pH-dependent anti-CD47 antibody that selectively targets solid tumors and improves therapeutic efficacy and safety. J Hematol Oncol, 16, 2023
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5YDM
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![BU of 5ydm by Molmil](/molmil-images/mine/5ydm) | |
5YDL
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![BU of 5ydl by Molmil](/molmil-images/mine/5ydl) | |
7E7C
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![BU of 7e7c by Molmil](/molmil-images/mine/7e7c) | |
5YDA
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![BU of 5yda by Molmil](/molmil-images/mine/5yda) | |
5VZT
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![BU of 5vzt by Molmil](/molmil-images/mine/5vzt) | Crystal structure of the Skp1-FBXO31 complex | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, F-box only protein 31, PHOSPHATE ION, ... | Authors: | Li, Y, Jin, K, Hao, B. | Deposit date: | 2017-05-29 | Release date: | 2018-01-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7UR2
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![BU of 7ur2 by Molmil](/molmil-images/mine/7ur2) | |
5VZU
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![BU of 5vzu by Molmil](/molmil-images/mine/5vzu) | Crystal structure of the Skp1-FBXO31-cyclin D1 complex | Descriptor: | Cyclin D1, F-box only protein 31, PHOSPHATE ION, ... | Authors: | Li, Y, Jin, K, Hao, B. | Deposit date: | 2017-05-29 | Release date: | 2018-01-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7E7A
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![BU of 7e7a by Molmil](/molmil-images/mine/7e7a) | Crystal structure of apo ENL YEATS domain T3 mutant | Descriptor: | Protein ENL | Authors: | Li, Y, Li, H. | Deposit date: | 2021-02-25 | Release date: | 2021-07-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Crystal structure of ENL YEATS domain T1 mutant in complex with histone H3 acetylation at K27 To Be Published
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7CWW
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![BU of 7cww by Molmil](/molmil-images/mine/7cww) | Crystal structure of TsrL | Descriptor: | 3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxaoctatriacontane-1,38-diol, TsrE | Authors: | Li, Y, Pan, L.F. | Deposit date: | 2020-08-31 | Release date: | 2021-09-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | crystal structure of TsrL To Be Published
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7F68
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![BU of 7f68 by Molmil](/molmil-images/mine/7f68) | Crystal structure of N-ras S89D | Descriptor: | GTPase NRas, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Li, Y, Sun, Q. | Deposit date: | 2021-06-24 | Release date: | 2022-06-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.24 Å) | Cite: | Crystal structure of N-ras S89D To Be Published
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6ZD4
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![BU of 6zd4 by Molmil](/molmil-images/mine/6zd4) | Crystal structure of YTHDC1 S378A mutant | Descriptor: | SULFATE ION, YTH domain containing 1 | Authors: | Bedi, R.K, Li, Y, Caflisch, A. | Deposit date: | 2020-06-13 | Release date: | 2021-01-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1. J Chem Theory Comput, 17, 2021
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6ZD3
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![BU of 6zd3 by Molmil](/molmil-images/mine/6zd3) | Crystal structure of YTHDC1 M438A mutant | Descriptor: | DI(HYDROXYETHYL)ETHER, SULFATE ION, YTH domain containing 1 | Authors: | Bedi, R.K, Li, Y, Caflisch, A. | Deposit date: | 2020-06-13 | Release date: | 2021-01-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1. J Chem Theory Comput, 17, 2021
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6ZD5
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![BU of 6zd5 by Molmil](/molmil-images/mine/6zd5) | |
6ZDA
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![BU of 6zda by Molmil](/molmil-images/mine/6zda) | |
6ZD8
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![BU of 6zd8 by Molmil](/molmil-images/mine/6zd8) | Crystal structure of YTHDC1 T379V mutant | Descriptor: | SULFATE ION, YTHDC1 | Authors: | Bedi, R.K, Li, Y, Caflisch, A. | Deposit date: | 2020-06-14 | Release date: | 2021-01-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1. J Chem Theory Comput, 17, 2021
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6DWO
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![BU of 6dwo by Molmil](/molmil-images/mine/6dwo) | |