4IQB
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![BU of 4iqb by Molmil](/molmil-images/mine/4iqb) | High Resolution Crystal Structure of C.elegans Thymidylate Synthase | Descriptor: | SULFATE ION, Thymidylate synthase | Authors: | Wilk, P, Dowiercial, A, Banaszak, K, Jarmula, A, Rypniewski, W, Rode, W. | Deposit date: | 2013-01-11 | Release date: | 2014-01-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.13 Å) | Cite: | Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS. J. Mol. Graph. Model., 77, 2017
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6MTE
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![BU of 6mte by Molmil](/molmil-images/mine/6mte) | Rabbit 80S ribosome with eEF2 and SERBP1 (rotated state) | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | Authors: | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | Deposit date: | 2018-10-19 | Release date: | 2018-11-21 | Last modified: | 2019-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of translationally inactive mammalian ribosomes. Elife, 7, 2018
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5NL9
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![BU of 5nl9 by Molmil](/molmil-images/mine/5nl9) | Crystal structure of a peroxide stress regulator from Leptospira interrogans | Descriptor: | POTASSIUM ION, Transcriptional regulator (FUR family), UNKNOWN ATOM OR ION, ... | Authors: | Saul, F.A, Haouz, A, Picardeau, M, Benaroudj, N. | Deposit date: | 2017-04-04 | Release date: | 2017-11-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and function of the Leptospira interrogans peroxide stress regulator (PerR), an atypical PerR devoid of a structural metal-binding site. J. Biol. Chem., 293, 2018
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2YGV
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![BU of 2ygv by Molmil](/molmil-images/mine/2ygv) | Conserved N-terminal domain of the yeast Histone Chaperone Asf1 in complex with the C-terminal fragment of Rad53 | Descriptor: | GLYCEROL, HISTONE CHAPERONE ASF1, SERINE/THREONINE-PROTEIN KINASE RAD53, ... | Authors: | Jiao, Y, Seeger, K, Murciano, B, Ledu, M.H, Charbonnier, J.B, Legrand, P, Lautrette, A, Gaubert, A, Mousson, F, Guerois, R, Mann, C, Ochsenbein, F. | Deposit date: | 2011-04-21 | Release date: | 2012-02-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.94 Å) | Cite: | Surprising Complexity of the Asf1 Histone Chaperone-Rad53 Kinase Interaction Proc.Natl.Acad.Sci.USA, 109, 2012
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6N0V
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![BU of 6n0v by Molmil](/molmil-images/mine/6n0v) | tRNA ligase | Descriptor: | MANGANESE (II) ION, tRNA ligase | Authors: | Banerjee, A, Goldgur, Y, Shuman, S. | Deposit date: | 2018-11-07 | Release date: | 2019-01-09 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (2.502 Å) | Cite: | Structure and two-metal mechanism of fungal tRNA ligase. Nucleic Acids Res., 47, 2019
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4J12
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![BU of 4j12 by Molmil](/molmil-images/mine/4j12) | monomeric Fc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, human Fc fragment | Authors: | Ishino, T, Wang, M, Mosyak, L, Tam, A, Duan, W, Svenson, K, Joyce, A, O'Hara, D, Lin, L, Somers, W, Kriz, R. | Deposit date: | 2013-01-31 | Release date: | 2013-05-01 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Engineering a Monomeric Fc Domain Modality by N-Glycosylation for the Half-life Extension of Biotherapeutics. J.Biol.Chem., 288, 2013
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6N1N
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![BU of 6n1n by Molmil](/molmil-images/mine/6n1n) | Crystal structure of class D beta-lactamase from Sebaldella termitidis ATCC 33386 | Descriptor: | Beta-lactamase, GLYCEROL, SULFATE ION | Authors: | Michalska, K, Tesar, C, Endres, M, Joachimiak, A, Satchell, K.J, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2018-11-09 | Release date: | 2018-12-19 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (1.601 Å) | Cite: | Crystal structure of class D beta-lactamase from Sebaldella termitidis ATCC 33386 To Be Published
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5NNL
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6N42
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2N59
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![BU of 2n59 by Molmil](/molmil-images/mine/2n59) | Solution Structure of R. palustris CsgH | Descriptor: | Putative uncharacterized protein CsgH | Authors: | Hawthorne, W.J, Taylor, J.D, Escalera-Maurer, A, Lambert, S, Koch, M, Scull, N, Sefer, L, Xu, Y, Matthews, S.J. | Deposit date: | 2015-07-13 | Release date: | 2016-05-11 | Method: | SOLUTION NMR | Cite: | Electrostatically-guided inhibition of Curli amyloid nucleation by the CsgC-like family of chaperones. Sci Rep, 6, 2016
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3J2N
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![BU of 3j2n by Molmil](/molmil-images/mine/3j2n) | The X-ray structure of the gp15 hexamer and the model of the gp18 protein fitted into the cryo-EM reconstruction of the contracted T4 tail | Descriptor: | Tail connector protein Gp15, Tail sheath protein Gp18 | Authors: | Fokine, A, Zhang, Z, Kanamaru, S, Bowman, V.D, Aksyuk, A, Arisaka, F, Rao, V.B, Rossmann, M.G. | Deposit date: | 2012-11-10 | Release date: | 2013-03-06 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (16 Å) | Cite: | The molecular architecture of the bacteriophage t4 neck. J.Mol.Biol., 425, 2013
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5NEK
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![BU of 5nek by Molmil](/molmil-images/mine/5nek) | Crystal structure of the polysaccharide deacetylase Bc1974 from Bacillus cereus in complex with acetazolamide | Descriptor: | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, ACETATE ION, Peptidoglycan N-acetylglucosamine deacetylase, ... | Authors: | Andreou, A, Giastas, P, Eliopoulos, E.E. | Deposit date: | 2017-03-10 | Release date: | 2018-02-21 | Last modified: | 2019-10-16 | Method: | X-RAY DIFFRACTION (3.057 Å) | Cite: | Structures of the Peptidoglycan N-Acetylglucosamine Deacetylase Bc1974 and Its Complexes with Zinc Metalloenzyme Inhibitors. Biochemistry, 57, 2018
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1G1B
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![BU of 1g1b by Molmil](/molmil-images/mine/1g1b) | CHORISMATE LYASE (WILD-TYPE) WITH BOUND PRODUCT | Descriptor: | CHORISMATE LYASE, P-HYDROXYBENZOIC ACID | Authors: | Gallagher, D.T, Mayhew, M, Holden, M.J, Kim, K.J, Howard, A, Vilker, V.L. | Deposit date: | 2000-10-11 | Release date: | 2001-04-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | The crystal structure of chorismate lyase shows a new fold and a tightly retained product. Proteins, 44, 2001
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8DU7
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![BU of 8du7 by Molmil](/molmil-images/mine/8du7) | Room-temperature serial synchrotron crystallography (SSX) structure of apo PTP1B | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 | Authors: | Ebrahim, A, Sharma, S, Keedy, D.A. | Deposit date: | 2022-07-27 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Room-temperature serial synchrotron crystallography of the human phosphatase PTP1B. Acta Crystallogr.,Sect.F, 79, 2023
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1JGE
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![BU of 1jge by Molmil](/molmil-images/mine/1jge) | HLA-B*2705 bound to nona-peptide m9 | Descriptor: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-27 B*2705 ALPHA CHAIN, ... | Authors: | Hulsmeyer, M, Hillig, R.C, Volz, A, Ruhl, M, Schroder, W, Saenger, W, Ziegler, A, Uchanska-Ziegler, B. | Deposit date: | 2001-06-25 | Release date: | 2002-10-30 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | HLA-B27 subtypes differentially associated with disease exhibit subtle structural
alterations J.Biol.Chem., 277, 2002
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6N8C
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![BU of 6n8c by Molmil](/molmil-images/mine/6n8c) | Structure of the Huntingtin tetramer/dimer mixture determined by paramagnetic NMR | Descriptor: | Huntingtin | Authors: | Schwieters, C.D, Kotler, S.A, Schmidt, T, Ceccon, A, Ghirlando, R, Libich, D.S, Clore, G.M. | Deposit date: | 2018-11-29 | Release date: | 2019-02-13 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Probing initial transient oligomerization events facilitating Huntingtin fibril nucleation at atomic resolution by relaxation-based NMR. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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7XQ7
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![BU of 7xq7 by Molmil](/molmil-images/mine/7xq7) | The complex structure of WT-Mpro | Descriptor: | 3C-like proteinase nsp5, SODIUM ION | Authors: | Sahoo, P, Lenka, D.R, Kumar, A. | Deposit date: | 2022-05-06 | Release date: | 2023-03-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Detailed Insights into the Inhibitory Mechanism of New Ebselen Derivatives against Main Protease (M pro ) of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Acs Pharmacol Transl Sci, 6, 2023
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5N5M
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7WYI
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![BU of 7wyi by Molmil](/molmil-images/mine/7wyi) | Native Photosystem I of Chlamydomonas reinhardtii | Descriptor: | CHLOROPHYLL A, CHLOROPHYLL A ISOMER, CHLOROPHYLL B, ... | Authors: | Kurisu, G, Gerle, C, Mitsuoka, K, Kawamoto, A, Tanaka, H. | Deposit date: | 2022-02-16 | Release date: | 2023-02-22 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Three structures of PSI-LHCI from Chlamydomonas reinhardtii suggest a resting state re-activated by ferredoxin. Biochim Biophys Acta Bioenerg, 1864, 2023
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4JL0
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![BU of 4jl0 by Molmil](/molmil-images/mine/4jl0) | Crystal structure of PcrH in complex with the chaperone binding region of PopB | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PopB, Regulatory protein PcrH | Authors: | Discola, K.F, Forster, A, Simorre, J.P, Attree, I, Dessen, A, Job, V. | Deposit date: | 2013-03-12 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Membrane and Chaperone Recognition by the Major Translocator Protein PopB of the Type III Secretion System of Pseudomonas aeruginosa. J.Biol.Chem., 289, 2014
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7WZN
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![BU of 7wzn by Molmil](/molmil-images/mine/7wzn) | PSI-LHCI from Chlamydomonas reinhardtii with bound ferredoxin | Descriptor: | CHLOROPHYLL A, CHLOROPHYLL A ISOMER, CHLOROPHYLL B, ... | Authors: | Kurisu, G, Gerle, C, Mitsuoka, K, Kawamoto, A, Tanaka, H. | Deposit date: | 2022-02-18 | Release date: | 2023-02-22 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Three structures of PSI-LHCI from Chlamydomonas reinhardtii suggest a resting state re-activated by ferredoxin. Biochim Biophys Acta Bioenerg, 1864, 2023
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3TU8
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![BU of 3tu8 by Molmil](/molmil-images/mine/3tu8) | Crystal Structure of the Burkholderia Lethal Factor 1 (BLF1) | Descriptor: | BROMIDE ION, Burkholderia Lethal Factor 1 (BLF1) | Authors: | Cruz, A, Hautbergue, G.M, Artymiuk, P.J, Baker, P.J, Chang, C.T, Mahadi, N.M, Mobbs, G.W, Mohamed, R, Nathan, S, Partridge, L.J, Raih, M.F, Ruzheinikov, S.N, Sedelnikova, S.E, Wilson, S.A, Rice, D.W. | Deposit date: | 2011-09-16 | Release date: | 2011-11-30 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (1.04 Å) | Cite: | A Burkholderia pseudomallei toxin inhibits helicase activity of translation factor eIF4A. Science, 334, 2011
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1XYO
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5N1C
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3K35
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![BU of 3k35 by Molmil](/molmil-images/mine/3k35) | Crystal Structure of Human SIRT6 | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, NAD-dependent deacetylase sirtuin-6, SULFATE ION, ... | Authors: | Pan, P.W, Dong, A, Qiu, W, Loppnau, P, Wang, J, Ravichandran, M, Bochkarev, A, Bountra, C, Weigelt, J, Arrowsmith, C.H, Min, J, Edwards, A.M, Structural Genomics Consortium (SGC) | Deposit date: | 2009-10-01 | Release date: | 2009-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and biochemical functions of SIRT6. J.Biol.Chem., 286, 2011
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