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8JE1
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BU of 8je1 by Molmil
An asymmetry dimer of the Cul2-Rbx1-EloBC-FEM1B ubiquitin ligase complexed with BEX2
Descriptor: Cullin-2, E3 ubiquitin-protein ligase RBX1, Elongin-B, ...
Authors:Dai, Z, Liang, L, Yin, Y.X.
Deposit date:2023-05-15
Release date:2024-02-28
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:Structural insights into the ubiquitylation strategy of the oligomeric CRL2 FEM1B E3 ubiquitin ligase.
Embo J., 43, 2024
8JE2
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BU of 8je2 by Molmil
Cryo-EM structure of neddylated Cul2-Rbx1-EloBC-FEM1B complexed with FNIP1-FLCN
Descriptor: Cullin-2, Elongin-B, Elongin-C, ...
Authors:Dai, Z, Liang, L, Yin, Y.X.
Deposit date:2023-05-15
Release date:2024-02-28
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:Structural insights into the ubiquitylation strategy of the oligomeric CRL2 FEM1B E3 ubiquitin ligase.
Embo J., 43, 2024
4FF5
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BU of 4ff5 by Molmil
Structure basis of a novel virulence factor GHIP a glycosyl hydrolase 25 of Streptococcus pneumoniae participating in host cell invasion
Descriptor: 1,2-ETHANEDIOL, Glycosyl hydrolase 25
Authors:Wang, D.
Deposit date:2012-05-31
Release date:2013-07-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural basis of the novel S. pneumoniae virulence factor, GHIP, a glycosyl hydrolase 25 participating in host-cell invasion.
Plos One, 8, 2013
6ERG
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BU of 6erg by Molmil
Complex of XLF and heterodimer Ku bound to DNA
Descriptor: DNA (21-MER), DNA (34-MER), Non-homologous end-joining factor 1, ...
Authors:Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B.
Deposit date:2017-10-18
Release date:2018-10-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nat. Struct. Mol. Biol., 25, 2018
6ERH
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BU of 6erh by Molmil
Complex of XLF and heterodimer Ku bound to DNA
Descriptor: DNA (21-MER), DNA (34-MER), Non-homologous end-joining factor 1, ...
Authors:Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B.
Deposit date:2017-10-18
Release date:2018-10-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nat. Struct. Mol. Biol., 25, 2018
6ERF
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BU of 6erf by Molmil
Complex of APLF factor and Ku heterodimer bound to DNA
Descriptor: Aprataxin and PNK-like factor, DNA (34-MER), DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*TP*TP*GP*GP*GP*CP*GP*CP*G)-3'), ...
Authors:Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B.
Deposit date:2017-10-18
Release date:2018-10-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nat.Struct.Mol.Biol., 25, 2018
8H7G
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BU of 8h7g by Molmil
Cryo-EM structure of the human SAGA complex
Descriptor: Ataxin-7, STAGA complex 65 subunit gamma, Splicing factor 3B subunit 3, ...
Authors:Huang, J, Zhang, Y.
Deposit date:2022-10-20
Release date:2022-12-14
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structure of human SAGA transcriptional coactivator complex.
Cell Discov, 8, 2022
5GWN
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BU of 5gwn by Molmil
Crystal structure of human RCC2
Descriptor: Protein RCC2, SULFATE ION
Authors:Liang, L, Yun, C.H, Yin, Y.X.
Deposit date:2016-09-12
Release date:2017-09-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.309 Å)
Cite:RCC2 is a novel p53 target in suppressing metastasis.
Oncogene, 37, 2018
5I9F
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BU of 5i9f by Molmil
Crystal structure of designed pentatricopeptide repeat protein dPPR-U10 in complex with its target RNA U10
Descriptor: RNA (5'-R(*GP*GP*GP*GP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*CP*CP*CP*C)-3'), pentatricopeptide repeat protein dPPR-U10
Authors:Shen, C, Zhang, D, Guan, Z, Zou, T, Yin, Y.
Deposit date:2016-02-20
Release date:2016-04-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.194 Å)
Cite:Structural basis for specific single-stranded RNA recognition by designer pentatricopeptide repeat proteins.
Nat Commun, 7, 2016
3S5L
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BU of 3s5l by Molmil
Crystal structure of CD4 mutant bound to HLA-DR1
Descriptor: GLYCEROL, HA peptide, HLA class II histocompatibility antigen DR beta chain, ...
Authors:Li, Y.
Deposit date:2011-05-23
Release date:2011-09-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex.
Proc.Natl.Acad.Sci.USA, 108, 2011
3S4S
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BU of 3s4s by Molmil
Crystal structure of CD4 mutant bound to HLA-DR1
Descriptor: GLYCEROL, HLA class II histocompatibility antigen, DR alpha chain, ...
Authors:Li, Y.
Deposit date:2011-05-20
Release date:2011-09-21
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex.
Proc.Natl.Acad.Sci.USA, 108, 2011
8TZ3
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BU of 8tz3 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with GS-441524, consensus reconstruction
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.31 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ7
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BU of 8tz7 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-INT1 conformation
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ5
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BU of 8tz5 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with N-hydroxycytidine
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxycytidine, SODIUM ION, ...
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.74 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZA
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BU of 8tza by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 2, INT2-INT1-INT1 conformation
Descriptor: N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ8
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BU of 8tz8 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-INT3 conformation
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ1
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BU of 8tz1 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Ribavirin
Descriptor: 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, ...
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ4
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BU of 8tz4 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with GS-441524, subset reconstruction
Descriptor: (2~{R},3~{R},4~{S},5~{R})-2-(4-azanylpyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolane-2-carbonitrile, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ9
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BU of 8tz9 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 2, INT2-INT2-INT2 conformation
Descriptor: N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ2
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BU of 8tz2 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in MSP2N2 nanodiscs, apo state
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZD
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BU of 8tzd by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-OFS conformation (3DVA analysis)
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ6
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BU of 8tz6 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with PSI-6206
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2'-deoxy-2'-fluoro-2'-methyluridine, SODIUM ION, ...
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
5K5X
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BU of 5k5x by Molmil
Crystal structure of human PDGFRA
Descriptor: Platelet-derived growth factor receptor alpha, SULFATE ION
Authors:Yan, X.E, Liang, L, Yun, C.H.
Deposit date:2016-05-24
Release date:2016-08-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.168 Å)
Cite:Structural and biochemical studies of the PDGFRA kinase domain
Biochem.Biophys.Res.Commun., 477, 2016
3OSV
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BU of 3osv by Molmil
The crytsal structure of FLGD from P. Aeruginosa
Descriptor: Flagellar basal-body rod modification protein FlgD, GLYCEROL
Authors:Wang, D, Luo, M, Niu, S.
Deposit date:2010-09-10
Release date:2011-05-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of a novel dimer form of FlgD from P. aeruginosa PAO1
Proteins, 79, 2011
4ZRZ
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BU of 4zrz by Molmil
PlyCB mutant R66E
Descriptor: PlyCB
Authors:Gallagher, D.T, Nelson, D.C, Shen, Y.
Deposit date:2015-05-12
Release date:2016-09-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:A bacteriophage endolysin that eliminates intracellular streptococci.
Elife, 5, 2016

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