6M63
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![BU of 6m63 by Molmil](/molmil-images/mine/6m63) | Crystal structure of a cAMP sensor G-Flamp1. | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Chimera of Cyclic nucleotide-gated potassium channel mll3241 and Yellow fluorescent protein | Authors: | Zhou, Z, Chen, S, Wang, L, Chu, J. | Deposit date: | 2020-03-12 | Release date: | 2021-09-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | A high-performance genetically encoded fluorescent indicator for in vivo cAMP imaging. Nat Commun, 13, 2022
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3IFU
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![BU of 3ifu by Molmil](/molmil-images/mine/3ifu) | The Crystal Structure of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Leader Protease Nsp1 | Descriptor: | Non-structural protein, ZINC ION | Authors: | Sun, Y, Xue, F, Guo, Y, Ma, M, Lou, Z, Rao, Z. | Deposit date: | 2009-07-26 | Release date: | 2009-10-27 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Crystal structure of porcine reproductive and respiratory syndrome virus leader protease Nsp1alpha J.Virol., 83, 2009
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7E7X
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![BU of 7e7x by Molmil](/molmil-images/mine/7e7x) | |
7E7Y
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![BU of 7e7y by Molmil](/molmil-images/mine/7e7y) | |
7E8C
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![BU of 7e8c by Molmil](/molmil-images/mine/7e8c) | SARS-CoV-2 S-6P in complex with 9 Fabs | Descriptor: | 368-2 H, 368-2 L, 604 H, ... | Authors: | Du, S, Xiao, J, Zhang, Z. | Deposit date: | 2021-03-01 | Release date: | 2021-06-09 | Last modified: | 2021-07-14 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines. Cell Res., 31, 2021
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7E88
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7E8F
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![BU of 7e8f by Molmil](/molmil-images/mine/7e8f) | SARS-CoV-2 NTD in complex with N9 Fab | Descriptor: | 368-2 H, 368-2 L, 604 H, ... | Authors: | Du, S, Xiao, J, Zhang, Z. | Deposit date: | 2021-03-01 | Release date: | 2021-06-09 | Last modified: | 2021-07-14 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines. Cell Res., 31, 2021
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7E86
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8I87
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![BU of 8i87 by Molmil](/molmil-images/mine/8i87) | Cryo-EM structure of TIR-APAZ/Ago-gRNA-DNA complex | Descriptor: | DNA (5'-D(P*TP*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*A)-3'), MAGNESIUM ION, Piwi domain-containing protein, ... | Authors: | Zhang, H, Deng, Z.Q, Yu, G.M, Li, X.Z, Wang, X.S. | Deposit date: | 2023-02-03 | Release date: | 2023-07-19 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insights into mechanisms of Argonaute protein-associated NADase activation in bacterial immunity. Cell Res., 33, 2023
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4DEQ
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![BU of 4deq by Molmil](/molmil-images/mine/4deq) | Structure of the Neuropilin-1/VEGF-A complex | Descriptor: | Neuropilin-1, Vascular endothelial growth factor A, PHOSPHATE ION | Authors: | Vander Kooi, C.W. | Deposit date: | 2012-01-21 | Release date: | 2012-02-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.649 Å) | Cite: | Structural Basis for Selective Vascular Endothelial Growth Factor-A (VEGF-A) Binding to Neuropilin-1. J.Biol.Chem., 287, 2012
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7FAU
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![BU of 7fau by Molmil](/molmil-images/mine/7fau) | Structure Determination of the NB1B11-RBD Complex | Descriptor: | NB_1B11, Spike protein S1, ZINC ION | Authors: | Shi, Z.Z, Li, X.X, Wang, L, Sun, Z.C, Zhang, H.W, Chen, X.C, Cui, Q.Q, Qiao, H.R, Lan, Z.Y, Zhang, X. | Deposit date: | 2021-07-07 | Release date: | 2022-06-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structural basis of nanobodies neutralizing SARS-CoV-2 variants. Structure, 30, 2022
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4EYC
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![BU of 4eyc by Molmil](/molmil-images/mine/4eyc) | Crystal structure of the cathelin-like domain of human cathelicidin LL-37 (hCLD) | Descriptor: | Cathelicidin antimicrobial peptide | Authors: | Pazgier, M, Pozharski, E, Toth, E, Lu, W. | Deposit date: | 2012-05-01 | Release date: | 2013-02-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and Functional Analysis of the Pro-Domain of Human Cathelicidin, LL-37. Biochemistry, 52, 2013
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5ZTL
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![BU of 5ztl by Molmil](/molmil-images/mine/5ztl) | Non-cryogenic structure of light-driven chloride pump having an NTQ motif | Descriptor: | CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ... | Authors: | Yun, J.H, Park, S.Y, Liu, H, Lee, W. | Deposit date: | 2018-05-04 | Release date: | 2018-12-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Non-cryogenic structure of a chloride pump provides crucial clues to temperature-dependent channel transport efficiency J. Biol. Chem., 294, 2019
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5ZTK
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![BU of 5ztk by Molmil](/molmil-images/mine/5ztk) | Synchrotron structure of light-driven chloride pump having an NTQ motif | Descriptor: | CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ... | Authors: | Yun, J.H, Park, J.H, Park, S.Y, Lee, W. | Deposit date: | 2018-05-04 | Release date: | 2018-12-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Non-cryogenic structure of a chloride pump provides crucial clues to temperature-dependent channel transport efficiency J. Biol. Chem., 294, 2019
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2M8T
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8HDO
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![BU of 8hdo by Molmil](/molmil-images/mine/8hdo) | Structure of A2BR bound to synthetic agonists BAY 60-6583 | Descriptor: | 2-[6-azanyl-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]pyridin-2-yl]sulfanylethanamide, Adenosine A2b receptor, CHOLESTEROL, ... | Authors: | Cai, H, Xu, Y, Xu, H.E, Jiang, Y. | Deposit date: | 2022-11-05 | Release date: | 2023-01-18 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Structures of adenosine receptor A 2B R bound to endogenous and synthetic agonists. Cell Discov, 8, 2022
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8HDP
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![BU of 8hdp by Molmil](/molmil-images/mine/8hdp) | Structure of A2BR bound to endogenous agonists adenosine | Descriptor: | ADENOSINE, Adenosine A2b receptor, CHOLESTEROL, ... | Authors: | Cai, H, Xu, Y, Xu, H.E, Jiang, Y. | Deposit date: | 2022-11-05 | Release date: | 2023-01-18 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structures of adenosine receptor A 2B R bound to endogenous and synthetic agonists. Cell Discov, 8, 2022
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8H1T
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![BU of 8h1t by Molmil](/molmil-images/mine/8h1t) | Cryo-EM structure of BAP1-ASXL1 bound to chromatosome | Descriptor: | DNA (187-MER), Histone H1.4, Histone H2A type 1-D, ... | Authors: | Ge, W, Yu, C, Xu, R.M. | Deposit date: | 2022-10-04 | Release date: | 2023-02-01 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Basis of the H2AK119 specificity of the Polycomb repressive deubiquitinase. Nature, 616, 2023
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8H2T
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![BU of 8h2t by Molmil](/molmil-images/mine/8h2t) | Cryo-EM structure of IadD/E dioxygenase bound with IAA | Descriptor: | 1H-INDOL-3-YLACETIC ACID, Aromatic-ring-hydroxylating dioxygenase beta subunit, FE (III) ION, ... | Authors: | Yu, G, Li, Z, Zhang, H. | Deposit date: | 2022-10-07 | Release date: | 2023-06-14 | Last modified: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (2.59 Å) | Cite: | Structural and biochemical characterization of the key components of an auxin degradation operon from the rhizosphere bacterium Variovorax. Plos Biol., 21, 2023
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7WRI
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![BU of 7wri by Molmil](/molmil-images/mine/7wri) | Cryo-EM structure of SARS-CoV-2 Omicron spike receptor-binding domain in complex with mouse ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein, ... | Authors: | Han, P, Xie, Y, Qi, J. | Deposit date: | 2022-01-26 | Release date: | 2022-06-08 | Last modified: | 2022-12-21 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Broader-species receptor binding and structural bases of Omicron SARS-CoV-2 to both mouse and palm-civet ACE2s. Cell Discov, 8, 2022
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7WSK
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![BU of 7wsk by Molmil](/molmil-images/mine/7wsk) | Crystal structure of SARS-CoV-2 Omicron spike receptor-binding domain in complex with civet ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike protein S1, ... | Authors: | Huang, B, Han, P, Qi, J. | Deposit date: | 2022-01-29 | Release date: | 2022-06-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Broader-species receptor binding and structural bases of Omicron SARS-CoV-2 to both mouse and palm-civet ACE2s. Cell Discov, 8, 2022
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2I03
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![BU of 2i03 by Molmil](/molmil-images/mine/2i03) | Crystal structure of human dipeptidyl peptidase 4 (DPP IV) with potent alkynyl cyanopyrrolidine (ABT-279) | Descriptor: | 2-[4-({2-[(2S,5R)-2-(AMINOMETHYL)-5-ETHYNYLPYRROLIDIN-1-YL]-2-OXOETHYL}AMINO)-4-METHYLPIPERIDIN-1-YL]ISONICOTINIC ACID, Dipeptidyl peptidase 4 | Authors: | Longenecker, K.L, Madar, D.J. | Deposit date: | 2006-08-09 | Release date: | 2006-12-12 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Discovery of 2-[4-{{2-(2S,5R)-2-cyano-5-ethynyl-1-pyrrolidinyl]-2-oxoethyl]amino]- 4-methyl-1-piperidinyl]-4-pyridinecarboxylic acid (ABT-279): a very potent, selective, effective, and well-tolerated inhibitor of dipeptidyl peptidase-IV, useful for the treatment of diabetes. J.Med.Chem., 49, 2006
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8W4O
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![BU of 8w4o by Molmil](/molmil-images/mine/8w4o) | Structure of PSII-FCPII-G/H complex in the PSII-FCPII supercomplex from Cyclotella meneghiniana | Descriptor: | (1~{R})-3,5,5-trimethyl-4-[(1~{E},3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E})-3,7,12,16-tetramethyl-18-[(4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-1,3,5,7,9,11,13,15-octaen-17-ynyl]cyclohex-3-en-1-ol, (3S,3'R,5R,6S,7cis)-7',8'-didehydro-5,6-dihydro-5,6-epoxy-beta,beta-carotene-3,3'-diol, (3S,3'S,5R,5'R,6S,6'R,8'R)-3,5'-dihydroxy-8-oxo-6',7'-didehydro-5,5',6,6',7,8-hexahydro-5,6-epoxy-beta,beta-caroten-3'- yl acetate, ... | Authors: | Shen, L.L, Li, Z.H, Shen, J.R, Wang, W.D. | Deposit date: | 2023-08-24 | Release date: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Structural insights into photosystem II supercomplex and trimeric FCP antennae of a centric diatom Cyclotella meneghiniana. Nat Commun, 14, 2023
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8X43
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![BU of 8x43 by Molmil](/molmil-images/mine/8x43) | human KCNQ2-CaM-Ebio1-S1 complex in the presence of PIP2 | Descriptor: | Calmodulin-1, N-(4-azanyl-1,2-dihydroacenaphthylen-5-yl)-4-fluoranyl-benzamide, Potassium voltage-gated channel subfamily KQT member 2 | Authors: | Ma, D, Guo, J. | Deposit date: | 2023-11-15 | Release date: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | A small-molecule activation mechanism that directly opens the KCNQ2 channel. Nat.Chem.Biol., 2024
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2O3C
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![BU of 2o3c by Molmil](/molmil-images/mine/2o3c) | Crystal structure of zebrafish Ape | Descriptor: | APEX nuclease 1, LEAD (II) ION | Authors: | Georgiadis, M.M, Gaur, R.K, Delaplane, S, Svenson, J. | Deposit date: | 2006-12-01 | Release date: | 2007-12-11 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease Mutat.Res., 643, 2008
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