8I87
Cryo-EM structure of TIR-APAZ/Ago-gRNA-DNA complex
Summary for 8I87
| Entry DOI | 10.2210/pdb8i87/pdb |
| EMDB information | 35240 |
| Descriptor | TIR domain-containing protein, Piwi domain-containing protein, DNA (5'-D(P*TP*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*A)-3'), ... (5 entities in total) |
| Functional Keywords | a protein complex, antiviral protein |
| Biological source | Maribacter polysiphoniae More |
| Total number of polymer chains | 16 |
| Total formula weight | 492958.84 |
| Authors | Zhang, H.,Deng, Z.Q.,Yu, G.M.,Li, X.Z.,Wang, X.S. (deposition date: 2023-02-03, release date: 2023-07-19, Last modification date: 2023-09-13) |
| Primary citation | Wang, X.,Li, X.,Yu, G.,Zhang, L.,Zhang, C.,Wang, Y.,Liao, F.,Wen, Y.,Yin, H.,Liu, X.,Wei, Y.,Li, Z.,Deng, Z.,Zhang, H. Structural insights into mechanisms of Argonaute protein-associated NADase activation in bacterial immunity. Cell Res., 33:699-711, 2023 Cited by PubMed: 37311833DOI: 10.1038/s41422-023-00839-7 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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