8I87

Cryo-EM structure of TIR-APAZ/Ago-gRNA-DNA complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, F, G (A, C, G, O)	TIR domain-containing protein	polymer	452	53270.6	4	UniProt (A0A316E683) Pfam (PF13676)	Maribacter polysiphoniae
2	B, D, E, H (B, D, F, T)	Piwi domain-containing protein	polymer	507	58091.4	4	UniProt (A0A316E3U6)	Maribacter polysiphoniae
3	I, L, M, P (E, J, K, U)	DNA (5'-D(P*TP*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*A)-3')	polymer	19	5692.7	4		Maribacter polysiphoniae
4	J, K, N, O (H, I, L, S)	RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*A)-3')	polymer	19	6160.7	4		Maribacter polysiphoniae
5	Q, R, S, T (B, D, F, H)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	492861.6
Non-Polymers*	Number of molecules	4
	Total formula weight	97.2
All*	Total formula weight	492958.8

*Water molecules are not included.