8XES
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![BU of 8xes by Molmil](/molmil-images/mine/8xes) | The structure of HLA-A/L1-1 | Descriptor: | Beta-2-microglobulin, HLA class I heavy chain, Major capsid protein L1 | Authors: | Zhang, J.N, Yue, C, Liu, J. | Deposit date: | 2023-12-12 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals. Immunohorizons, 8, 2024
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8XFZ
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![BU of 8xfz by Molmil](/molmil-images/mine/8xfz) | The structure of HLA-A/L1-2 | Descriptor: | Beta-2-microglobulin, HLA class I heavy chain, Major capsid protein L1 | Authors: | Zhang, J.N, Yue, C, Liu, J. | Deposit date: | 2023-12-14 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals. Immunohorizons, 8, 2024
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8XKE
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![BU of 8xke by Molmil](/molmil-images/mine/8xke) | The structure of HLA-A/14-3-D | Descriptor: | Beta-2-microglobulin, GLU-VAL-ASP-ASN-ALA-THR-ARG-PHE-ALA-SER-VAL-TYR, HLA class I heavy chain | Authors: | Zhang, J.N, Yue, C, Liu, J, Sun, Z.Y. | Deposit date: | 2023-12-23 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals. Immunohorizons, 8, 2024
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8XKC
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![BU of 8xkc by Molmil](/molmil-images/mine/8xkc) | The structure of HLA-A/Pep16 | Descriptor: | Beta-2-microglobulin, HLA class I heavy chain, Spike protein S1 | Authors: | Zhang, J.N, Yue, C, Liu, J. | Deposit date: | 2023-12-23 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals. Immunohorizons, 8, 2024
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4W5S
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![BU of 4w5s by Molmil](/molmil-images/mine/4w5s) | Tankyrase in complex with compound | Descriptor: | 8-(hydroxymethyl)-2-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]quinazolin-4(3H)-one, GLYCEROL, Tankyrase-1, ... | Authors: | Johannes, J, Kazmirski, S.L, Boriack-Sjodin, P.A, Howard, T. | Deposit date: | 2014-08-18 | Release date: | 2015-05-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Pyrimidinone nicotinamide mimetics as selective tankyrase and wnt pathway inhibitors suitable for in vivo pharmacology. Acs Med.Chem.Lett., 6, 2015
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8HKQ
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![BU of 8hkq by Molmil](/molmil-images/mine/8hkq) | ion channel | Descriptor: | POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ... | Authors: | Jiang, D.H, Zhang, J.T. | Deposit date: | 2022-11-27 | Release date: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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8HKK
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![BU of 8hkk by Molmil](/molmil-images/mine/8hkk) | ion channel | Descriptor: | POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ... | Authors: | Jiang, D.H, Zhang, J.T. | Deposit date: | 2022-11-27 | Release date: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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8HIR
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![BU of 8hir by Molmil](/molmil-images/mine/8hir) | potassium channels | Descriptor: | POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ... | Authors: | Jiang, D.H, Zhang, J.T. | Deposit date: | 2022-11-21 | Release date: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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8HKM
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![BU of 8hkm by Molmil](/molmil-images/mine/8hkm) | ion channel | Descriptor: | POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION, ... | Authors: | Jiang, D.H, Zhang, J.T. | Deposit date: | 2022-11-27 | Release date: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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8HK6
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![BU of 8hk6 by Molmil](/molmil-images/mine/8hk6) | potassium channel | Descriptor: | POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION | Authors: | Jiang, D.H, Zhang, J.T. | Deposit date: | 2022-11-25 | Release date: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (2.64 Å) | Cite: | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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8HKF
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![BU of 8hkf by Molmil](/molmil-images/mine/8hkf) | ion channel | Descriptor: | POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION | Authors: | Jiang, D.H, Zhang, Z.T. | Deposit date: | 2022-11-25 | Release date: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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5KX7
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![BU of 5kx7 by Molmil](/molmil-images/mine/5kx7) | Irak4-inhibitor co-structure | Descriptor: | Interleukin-1 receptor-associated kinase 4, ~{N}-(3-aminocarbonyl-1-methyl-pyrazol-4-yl)-6-(1-methylpyrazol-4-yl)pyridine-2-carboxamide | Authors: | Fischmann, T.O. | Deposit date: | 2016-07-20 | Release date: | 2016-08-17 | Last modified: | 2016-08-24 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Efforts towards the optimization of a bi-aryl class of potent IRAK4 inhibitors. Bioorg.Med.Chem.Lett., 26, 2016
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8FY5
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![BU of 8fy5 by Molmil](/molmil-images/mine/8fy5) | Human TMEM175-LAMP1 full-length complex | Descriptor: | Endosomal/lysosomal potassium channel TMEM175, Lysosome-associated membrane glycoprotein 1 | Authors: | Zhang, J.Y, Zeng, W.Z, Han, Y, Jiang, Y.X. | Deposit date: | 2023-01-25 | Release date: | 2023-06-28 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel. Mol.Cell, 83, 2023
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8FYF
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![BU of 8fyf by Molmil](/molmil-images/mine/8fyf) | Human TMEM175-LAMP1 transmembrane domain only complex | Descriptor: | Endosomal/lysosomal potassium channel TMEM175, Lysosome-associated membrane glycoprotein 1 | Authors: | Zhang, J.Y, Zeng, W.Z, Han, Y, Jiang, Y.X. | Deposit date: | 2023-01-26 | Release date: | 2023-06-28 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel. Mol.Cell, 83, 2023
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8DZP
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![BU of 8dzp by Molmil](/molmil-images/mine/8dzp) | momSalB bound Kappa Opioid Receptor in complex with Gi1 | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Fay, J.F, Che, T. | Deposit date: | 2022-08-08 | Release date: | 2023-05-03 | Last modified: | 2023-05-24 | Method: | ELECTRON MICROSCOPY (2.71 Å) | Cite: | Ligand and G-protein selectivity in the kappa-opioid receptor. Nature, 617, 2023
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8DZQ
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![BU of 8dzq by Molmil](/molmil-images/mine/8dzq) | momSalB bound Kappa Opioid Receptor in complex with GoA | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(o) subunit alpha, ... | Authors: | Fay, J.F, Che, T. | Deposit date: | 2022-08-08 | Release date: | 2023-05-03 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (2.82 Å) | Cite: | Ligand and G-protein selectivity in the kappa-opioid receptor. Nature, 617, 2023
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8DZS
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![BU of 8dzs by Molmil](/molmil-images/mine/8dzs) | GR89,696 bound Kappa Opioid Receptor in complex with Gz | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(z) subunit alpha, ... | Authors: | Fay, J.F, Che, T. | Deposit date: | 2022-08-08 | Release date: | 2023-05-03 | Last modified: | 2023-05-24 | Method: | ELECTRON MICROSCOPY (2.65 Å) | Cite: | Ligand and G-protein selectivity in the kappa-opioid receptor. Nature, 617, 2023
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8DZR
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![BU of 8dzr by Molmil](/molmil-images/mine/8dzr) | GR89,696 bound Kappa Opioid Receptor in complex with gustducin | Descriptor: | G alpha gustducin protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Fay, J.F, Che, T. | Deposit date: | 2022-08-08 | Release date: | 2023-05-03 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (2.61 Å) | Cite: | Ligand and G-protein selectivity in the kappa-opioid receptor. Nature, 617, 2023
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6DGT
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![BU of 6dgt by Molmil](/molmil-images/mine/6dgt) | Selective PI3K beta inhibitor bound to PI3K delta | Descriptor: | 4-[1-(5,8-difluoroquinolin-4-yl)-2-methyl-4-(4H-1,2,4-triazol-3-yl)-1H-benzimidazol-6-yl]-3-fluoropyridin-2-amine, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | Authors: | Somoza, J, Villasenor, A, McGrath, M. | Deposit date: | 2018-05-18 | Release date: | 2018-08-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Atropisomerism by Design: Discovery of a Selective and Stable Phosphoinositide 3-Kinase (PI3K) beta Inhibitor. J. Med. Chem., 61, 2018
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6XDG
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![BU of 6xdg by Molmil](/molmil-images/mine/6xdg) | Complex of SARS-CoV-2 receptor binding domain with the Fab fragments of two neutralizing antibodies | Descriptor: | REGN10933 antibody Fab fragment heavy chain, REGN10933 antibody Fab fragment light chain, REGN10987 antibody Fab fragment heavy chain, ... | Authors: | Franklin, M.C, Saotome, K, Romero Hernandez, A, Zhou, Y. | Deposit date: | 2020-06-10 | Release date: | 2020-06-24 | Last modified: | 2021-01-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail. Science, 369, 2020
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7C6O
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![BU of 7c6o by Molmil](/molmil-images/mine/7c6o) | |
3UL8
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![BU of 3ul8 by Molmil](/molmil-images/mine/3ul8) | Crystal structure of the TV3 mutant V134L | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Toll-like receptor 4, ... | Authors: | Kim, H.J, Cheong, H.K, Jeon, Y.H. | Deposit date: | 2011-11-10 | Release date: | 2012-04-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein. Plos One, 7, 2012
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3ULA
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![BU of 3ula by Molmil](/molmil-images/mine/3ula) | Crystal structure of the TV3 mutant F63W-MD-2-Eritoran complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-O-DECYL-2-DEOXY-6-O-{2-DEOXY-3-O-[(3R)-3-METHOXYDECYL]-6-O-METHYL-2-[(11Z)-OCTADEC-11-ENOYLAMINO]-4-O-PHOSPHONO-BETA-D-GLUCOPYRANOSYL}-2-[(3-OXOTETRADECANOYL)AMINO]-1-O-PHOSPHONO-ALPHA-D-GLUCOPYRANOSE, Lymphocyte antigen 96, ... | Authors: | Kim, H.J, Cheong, H.K, Jeon, Y.H. | Deposit date: | 2011-11-10 | Release date: | 2012-04-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein. Plos One, 7, 2012
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3UL7
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![BU of 3ul7 by Molmil](/molmil-images/mine/3ul7) | Crystal structure of the TV3 mutant F63W | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Toll-like receptor 4, ... | Authors: | Kim, H.J, Cheong, H.K, Jeon, Y.H. | Deposit date: | 2011-11-10 | Release date: | 2012-04-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein. Plos One, 7, 2012
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3UL9
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![BU of 3ul9 by Molmil](/molmil-images/mine/3ul9) | structure of the TV3 mutant M41E | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Toll-like receptor 4, ... | Authors: | Kim, H.J, Cheong, H.K, Jeon, Y.H. | Deposit date: | 2011-11-10 | Release date: | 2012-05-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure-Based Rational Design of a Toll-like Receptor 4 (TLR4) Decoy Receptor with High Binding Affinity for a Target Protein. Plos One, 7, 2012
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