8DZQ

momSalB bound Kappa Opioid Receptor in complex with GoA

Summary for 8DZQ

• Entry DOI: 10.2210/pdb8dzq/pdb
• EMDB information: 27804 27805 27806 27807
• Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ScFv16 protein, ... (6 entities in total)
• Functional Keywords: gpcr, receptor, kappa, kor, opioid, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 147271.07

Authors

Fay, J.F.,Che, T. (deposition date: 2022-08-08, release date: 2023-05-03, Last modification date: 2023-09-20)

• Primary citation: Han, J.,Zhang, J.,Nazarova, A.L.,Bernhard, S.M.,Krumm, B.E.,Zhao, L.,Lam, J.H.,Rangari, V.A.,Majumdar, S.,Nichols, D.E.,Katritch, V.,Yuan, P.,Fay, J.F.,Che, T.; Ligand and G-protein selectivity in the kappa-opioid receptor.; Nature, 617:417-425, 2023; PubMed: 37138078; DOI: 10.1038/s41586-023-06030-7

Experimental method

ELECTRON MICROSCOPY (2.82 Å)