8DZQ

momSalB bound Kappa Opioid Receptor in complex with GoA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	C	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	polymer	339	37285.7	1	UniProt (P62873) Pfam (PF00400) In PDB	Homo sapiens (human)	Transducin beta chain 1
2	D	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2	polymer	71	7861.1	1	UniProt (P59768) Pfam (PF00631) In PDB	Homo sapiens (human)	G gamma-I
3	E	ScFv16 protein	polymer	251	26679.7	1		Mus musculus (Mouse)
4	B	Guanine nucleotide-binding protein G(o) subunit alpha	polymer	354	40081.4	1	UniProt (P09471) Pfam (PF00503) In PDB	Homo sapiens (human)
5	A	Kappa-type opioid receptor	polymer	308	34928.6	1	UniProt (P41145) Pfam (PF00001) In PDB	Homo sapiens (human)	K-OR-1,KOR-1
6	A	methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-9-(methoxymethoxy)-6a,10b-dimethyl-4,10-dioxododecahydro-2H-naphtho[2,1-c]pyran-7-carboxylate	non-polymer		434.5	1	Chemie (U99)

Sequence modifications

B: 1 - 354 (UniProt: P09471)

PDB	External Database	Details
Ser 3	Cys 3	conflict
Asn 47	Ser 47	conflict
Ala 204	Gly 204	conflict
Ala 246	Glu 246	conflict
Lys 249	Met 249	conflict
Ser 326	Ala 326	conflict

A: 54 - 358 (UniProt: P41145)

PDB	External Database	Details
Leu 51	-	expression tag
Gly 52	-	expression tag
Ser 53	-	expression tag
Leu 135	Ile 135	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	146836.6
Non-Polymers*	Number of molecules	1
	Total formula weight	434.5
All*	Total formula weight	147271.1

*Water molecules are not included.