8DZQ
momSalB bound Kappa Opioid Receptor in complex with GoA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 339 | 37285.7 | 1 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (human) | Transducin beta chain 1 |
| 2 | B (D) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 3 | C (E) | ScFv16 protein | polymer | 251 | 26679.7 | 1 | Mus musculus (Mouse) | ||
| 4 | D (B) | Guanine nucleotide-binding protein G(o) subunit alpha | polymer | 354 | 40081.4 | 1 | UniProt (P09471) Pfam (PF00503) | Homo sapiens (human) | |
| 5 | E (A) | Kappa-type opioid receptor | polymer | 308 | 34928.6 | 1 | UniProt (P41145) Pfam (PF00001) | Homo sapiens (human) | K-OR-1,KOR-1 |
| 6 | F (A) | methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-9-(methoxymethoxy)-6a,10b-dimethyl-4,10-dioxododecahydro-2H-naphtho[2,1-c]pyran-7-carboxylate | non-polymer | 434.5 | 1 | Chemie (U99) |
Sequence modifications
B: 1 - 354 (UniProt: P09471)
A: 54 - 358 (UniProt: P41145)
| PDB | External Database | Details |
|---|---|---|
| Ser 3 | Cys 3 | conflict |
| Asn 47 | Ser 47 | conflict |
| Ala 204 | Gly 204 | conflict |
| Ala 246 | Glu 246 | conflict |
| Lys 249 | Met 249 | conflict |
| Ser 326 | Ala 326 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Leu 51 | - | expression tag |
| Gly 52 | - | expression tag |
| Ser 53 | - | expression tag |
| Leu 135 | Ile 135 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 146836.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 434.5 | |
| All* | Total formula weight | 147271.1 |
