3SYN
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![BU of 3syn by Molmil](/molmil-images/mine/3syn) | Crystal structure of FlhF in complex with its activator | Descriptor: | ALUMINUM FLUORIDE, ATP-binding protein YlxH, Flagellar biosynthesis protein flhF, ... | Authors: | Bange, G, Kuemmerer, N, Wild, K, Sinning, I. | Deposit date: | 2011-07-18 | Release date: | 2011-11-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.063 Å) | Cite: | Structural basis for the molecular evolution of SRP-GTPase activation by protein. Nat.Struct.Mol.Biol., 18, 2011
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3DEO
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![BU of 3deo by Molmil](/molmil-images/mine/3deo) | |
3DEP
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![BU of 3dep by Molmil](/molmil-images/mine/3dep) | Structural basis for specific substrate recognition by the chloroplast signal recognition particle protein cpSRP43 | Descriptor: | CHLORIDE ION, Signal recognition particle 43 kDa protein, YPGGSFDPLGLA | Authors: | Holdermann, I, Stengel, K.F, Wild, K, Sinning, I. | Deposit date: | 2008-06-10 | Release date: | 2008-08-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for specific substrate recognition by the chloroplast signal recognition particle protein cpSRP43. Science, 321, 2008
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1QZW
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![BU of 1qzw by Molmil](/molmil-images/mine/1qzw) | Crystal structure of the complete core of archaeal SRP and implications for inter-domain communication | Descriptor: | 7S RNA, Signal recognition 54 kDa protein | Authors: | Rosendal, K.R, Wild, K, Montoya, G, Sinning, I. | Deposit date: | 2003-09-18 | Release date: | 2003-11-18 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Crystal structure of the complete core of archaeal signal recognition particle and implications for interdomain communication Proc.Natl.Acad.Sci.USA, 100, 2003
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1QZX
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![BU of 1qzx by Molmil](/molmil-images/mine/1qzx) | |
2J28
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![BU of 2j28 by Molmil](/molmil-images/mine/2j28) | MODEL OF E. COLI SRP BOUND TO 70S RNCS | Descriptor: | 23S RIBOSOMAL RNA, 4.5S SIGNAL RECOGNITION PARTICLE RNA, 50S ribosomal protein L11, ... | Authors: | Halic, M, Blau, M, Becker, T, Mielke, T, Pool, M.R, Wild, K, Sinning, I, Beckmann, R. | Deposit date: | 2006-08-16 | Release date: | 2006-11-08 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.5 Å) | Cite: | Following the Signal Sequence from Ribosomal Tunnel Exit to Signal Recognition Particle Nature, 444, 2006
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2J37
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![BU of 2j37 by Molmil](/molmil-images/mine/2j37) | MODEL OF MAMMALIAN SRP BOUND TO 80S RNCS | Descriptor: | 60S RIBOSOMAL PROTEIN L23, RIBOSOMAL PROTEIN L31, RIBOSOMAL PROTEIN L35, ... | Authors: | Halic, M, Blau, M, Becker, T, Mielke, T, Pool, M.R, Wild, K, Sinning, I, Beckmann, R. | Deposit date: | 2006-08-18 | Release date: | 2006-11-08 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8.7 Å) | Cite: | Following the signal sequence from ribosomal tunnel exit to signal recognition particle. Nature, 444, 2006
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2PX3
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![BU of 2px3 by Molmil](/molmil-images/mine/2px3) | Crystal structure of FlhF complexed with GTP/Mg(2+) | Descriptor: | Flagellar biosynthesis protein flhF, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | Authors: | Bange, G, Wild, K, Sinning, I. | Deposit date: | 2007-05-14 | Release date: | 2007-09-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The crystal structure of the third signal-recognition particle GTPase FlhF reveals a homodimer with bound GTP. Proc.Natl.Acad.Sci.Usa, 104, 2007
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1E8O
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![BU of 1e8o by Molmil](/molmil-images/mine/1e8o) | Core of the Alu domain of the mammalian SRP | Descriptor: | 7SL RNA, SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN, SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN, ... | Authors: | Weichenrieder, O, Wild, K, Strub, K, Cusack, S. | Deposit date: | 2000-09-28 | Release date: | 2000-11-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure and Assembly of the Alu Domain of the Mammalian Signal Recognition Particle Nature, 408, 2000
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2PX0
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![BU of 2px0 by Molmil](/molmil-images/mine/2px0) | Crystal structure of FlhF complexed with GMPPNP/Mg(2+) | Descriptor: | Flagellar biosynthesis protein flhF, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Bange, G, Wild, K, Sinning, I. | Deposit date: | 2007-05-14 | Release date: | 2007-09-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The crystal structure of the third signal-recognition particle GTPase FlhF reveals a homodimer with bound GTP. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2Q8K
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![BU of 2q8k by Molmil](/molmil-images/mine/2q8k) | The crystal structure of Ebp1 | Descriptor: | GLYCEROL, Proliferation-associated protein 2G4, SULFATE ION | Authors: | Kowalinski, E, Bange, G, Wild, K, Sinning, I. | Deposit date: | 2007-06-11 | Release date: | 2007-09-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The crystal structure of Ebp1 reveals a methionine aminopeptidase fold as binding platform for multiple interactions. Febs Lett., 581, 2007
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1E8S
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![BU of 1e8s by Molmil](/molmil-images/mine/1e8s) | Alu domain of the mammalian SRP (potential Alu retroposition intermediate) | Descriptor: | 7SL RNA, 88-MER, EUROPIUM (III) ION, ... | Authors: | Weichenrieder, O, Wild, K, Strub, K, Cusack, S. | Deposit date: | 2000-09-29 | Release date: | 2000-11-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structure and Assembly of the Alu Domain of the Mammalian Signal Recognition Particle Nature, 408, 2000
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2YHS
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![BU of 2yhs by Molmil](/molmil-images/mine/2yhs) | Structure of the E. coli SRP receptor FtsY | Descriptor: | 1,2-ETHANEDIOL, CELL DIVISION PROTEIN FTSY | Authors: | Stjepanovic, G, Bange, G, Wild, K, Sinning, I. | Deposit date: | 2011-05-05 | Release date: | 2011-05-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Lipids Trigger a Conformational Switch that Regulates Signal Recognition Particle (Srp)-Mediated Protein Targeting. J.Biol.Chem., 286, 2011
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2FH5
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![BU of 2fh5 by Molmil](/molmil-images/mine/2fh5) | The Structure of the Mammalian SRP Receptor | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Signal recognition particle receptor alpha subunit, ... | Authors: | Schlenker, O, Wild, K, Sinning, I. | Deposit date: | 2005-12-23 | Release date: | 2006-01-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | The structure of the mammalian signal recognition particle (SRP) receptor as prototype for the interaction of small GTPases with Longin domains. J.Biol.Chem., 281, 2006
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3UI2
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![BU of 3ui2 by Molmil](/molmil-images/mine/3ui2) | |
3B9Q
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![BU of 3b9q by Molmil](/molmil-images/mine/3b9q) | The crystal structure of cpFtsY from Arabidopsis thaliana | Descriptor: | Chloroplast SRP receptor homolog, alpha subunit CPFTSY, MALONATE ION | Authors: | Stengel, K.F, Wild, K, Sinning, I. | Deposit date: | 2007-11-06 | Release date: | 2007-12-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The structure of the chloroplast signal recognition particle (SRP) receptor reveals mechanistic details of SRP GTPase activation and a conserved membrane targeting site Febs Lett., 581, 2007
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5TBD
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![BU of 5tbd by Molmil](/molmil-images/mine/5tbd) | Crystal Structure of anti-MSP2 Fv fragment (mAb4D11) in complex with 3D7-MSP2 215-222 | Descriptor: | Fv fragment (mAb4D1) heavy chain, Merozoite surface protein 2 | Authors: | Seow, J, Morales, R.A.V, MacRaild, C.A, Bankala, K, Drinkwater, N, Dingjan, T, Jaipuria, G, Wilde, K, Anders, R.F, Atreya, H.S, Christ, D, McGowan, S, Norton, R.S. | Deposit date: | 2016-09-12 | Release date: | 2017-02-15 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure and Characterisation of a Key Epitope in the Conserved C-Terminal Domain of the Malaria Vaccine Candidate MSP2. J. Mol. Biol., 429, 2017
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3KL4
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![BU of 3kl4 by Molmil](/molmil-images/mine/3kl4) | Recognition of a signal peptide by the signal recognition particle | Descriptor: | Signal peptide of yeast dipeptidyl aminopeptidase B, Signal recognition 54 kDa protein | Authors: | Janda, C.Y, Nagai, K, Li, J, Oubridge, C. | Deposit date: | 2009-11-06 | Release date: | 2010-03-31 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Recognition of a signal peptide by the signal recognition particle. Nature, 465, 2010
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1E2K
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![BU of 1e2k by Molmil](/molmil-images/mine/1e2k) | Kinetics and crystal structure of the wild-type and the engineered Y101F mutant of Herpes simplex virus type 1 thymidine kinase interacting with (North)-methanocarba-thymidine | Descriptor: | 1-[4-HYDROXY-5-(HYDROXYMETHYL)BICYCLO[3.1.0]HEX-2-YL]-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE, SULFATE ION, THYMIDINE KINASE | Authors: | Vogt, J, Scapozza, L, Schulz, G.E. | Deposit date: | 2000-05-23 | Release date: | 2000-08-19 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Kinetics and Crystal Structure of the Wild-Type and the Engineered Y101F Mutant of Herpes Simplex Virus Type 1 Thymidine Kinase Interacting with (North)-Methanocarba-Thymidine Biochemistry, 39, 2000
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1E2L
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![BU of 1e2l by Molmil](/molmil-images/mine/1e2l) | Kinetics and crystal structure of the wild-type and the engineered Y101F mutant of Herpes simplex virus type 1 thymidine kinase interacting with (North)-methanocarba-thymidine | Descriptor: | 1-[4-HYDROXY-5-(HYDROXYMETHYL)BICYCLO[3.1.0]HEX-2-YL]-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE, SULFATE ION, THYMIDINE KINASE | Authors: | Vogt, J, Scapozza, L, Schulz, G.E. | Deposit date: | 2000-05-23 | Release date: | 2000-08-18 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Kinetics and Crystal Structure of the Wild-Type and the Engineered Y101F Mutant of Herpes Simplex Virus Type 1 Thymidine Kinase Interacting with (North)-Methanocarba-Thymidine Biochemistry, 39, 2000
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2N88
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![BU of 2n88 by Molmil](/molmil-images/mine/2n88) | Chromodomain 3 (CD3) of cpSRP43 | Descriptor: | Signal recognition particle 43 kDa protein, chloroplastic | Authors: | Hennig, J, Sattler, M. | Deposit date: | 2015-10-06 | Release date: | 2015-12-09 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural basis for cpSRP43 chromodomain selectivity and dynamics in Alb3 insertase interaction. Nat Commun, 6, 2015
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1OF1
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![BU of 1of1 by Molmil](/molmil-images/mine/1of1) | KINETICS AND CRYSTAL STRUCTURE OF THE HERPES SIMPLEX VIRUS TYPE 1 THYMIDINE KINASE INTERACTING WITH (SOUTH)-METHANOCARBA-THYMIDINE | Descriptor: | (SOUTH)-METHANOCARBA-THYMIDINE, SULFATE ION, THYMIDINE KINASE | Authors: | Claus, M.T, Schelling, P, Folkers, G, Marquez, V.E, Scapozza, L, Schulz, G.E. | Deposit date: | 2003-04-03 | Release date: | 2004-06-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Biochemical and Structural Characterization of (South)-Methanocarbathymidine that Specifically Inhibits Growth of Herpes Simplex Virus Type 1 Thymidine Kinase-Transduced Osteosarcoma Cells J.Biol.Chem., 279, 2004
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3BS6
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![BU of 3bs6 by Molmil](/molmil-images/mine/3bs6) | |
3F0T
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![BU of 3f0t by Molmil](/molmil-images/mine/3f0t) | Crystal structure of thymidine kinase from Herpes simplex virus type 1 in complex with N-methyl-DHBT | Descriptor: | N-Methyl-6-(1,3-dihydroxy-isobutyl)thymine, SULFATE ION, Thymidine kinase | Authors: | Pernot, L, Perozzo, R, Westermaier, Y, Martic, M, Ametamey, S, Scapozza, L. | Deposit date: | 2008-10-26 | Release date: | 2009-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Synthesis, crystal structure, and in vitro biological evaluation of C-6 pyrimidine derivatives: new lead structures for monitoring gene expression in vivo. Nucleosides Nucleotides Nucleic Acids, 30, 2011
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1E2N
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![BU of 1e2n by Molmil](/molmil-images/mine/1e2n) | HPT + HMTT | Descriptor: | 6-{[4-(HYDROXYMETHYL)-5-METHYL-2,6-DIOXOHEXAHYDROPYRIMIDIN-5-YL]METHYL}-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE, SULFATE ION, THYMIDINE KINASE | Authors: | Vogt, J, Scapozza, L, Schulz, G.E. | Deposit date: | 2000-05-23 | Release date: | 2001-03-31 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Effect of Substrate Binding on the Conformation and Structural Stability of Herpes Simplex Virus Type 1 Thymidine Kinase Protein Sci., 10, 2001
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