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4N4W
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BU of 4n4w by Molmil
Structure of the human smoothened receptor in complex with SANT-1.
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (E)-N-(4-benzylpiperazin-1-yl)-1-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methanimine, Cytochrome b(562),Smoothened homolog, ...
Authors:Wang, C, Wu, H, Han, G.W, Cherezov, V, Stevens, R.C, GPCR Network (GPCR)
Deposit date:2013-10-08
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs.
Nat Commun, 5, 2014
2LGK
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BU of 2lgk by Molmil
NMR Structure of UHRF1 PHD domains in a complex with histone H3 peptide
Descriptor: E3 ubiquitin-protein ligase UHRF1, ZINC ION, histone H3 peptide
Authors:Wang, C, Shen, J, Yang, Z, Chen, P, Zhao, B, Hu, W, Lan, W, Tong, X, Wu, H, Li, G, Cao, C.
Deposit date:2011-07-28
Release date:2011-09-28
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis for site-specific reading of unmodified R2 of histone H3 tail by UHRF1 PHD finger.
Cell Res., 21, 2011
2LGG
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BU of 2lgg by Molmil
Structure of PHD domain of UHRF1 in complex with H3 peptide
Descriptor: E3 ubiquitin-protein ligase UHRF1, ZINC ION, histone H3 peptide
Authors:Wang, C, Shen, J, Yang, Z, Chen, P, Zhao, B, Hu, W, Lan, W, Tong, X, Wu, H, Li, G, Cao, C.
Deposit date:2011-07-26
Release date:2011-09-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis for site-specific reading of unmodified R2 of histone H3 tail by UHRF1 PHD finger.
Cell Res., 21, 2011
2LGL
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BU of 2lgl by Molmil
NMR structure of the UHRF1 PHD domain
Descriptor: E3 ubiquitin-protein ligase UHRF1, ZINC ION
Authors:Wang, C, Shen, J, Yang, Z, Chen, P, Zhao, B, Hu, W, Lan, W, Tong, X, Wu, H, Li, G, Cao, C.
Deposit date:2011-07-28
Release date:2011-09-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis for site-specific reading of unmodified R2 of histone H3 tail by UHRF1 PHD finger.
Cell Res., 21, 2011
2QYO
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BU of 2qyo by Molmil
Crystal structure of isoflavone O-methyltransferase homolog in complex with biochanin A and SAH
Descriptor: 5,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one, O-methyltransferase, POTASSIUM ION, ...
Authors:Wang, C, Yu, X.-H, Liu, C.-J.
Deposit date:2007-08-15
Release date:2008-08-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structures of Medicago truncatula isoflavone O-methyltransferase reveal conserved surface binding motifs critical for enzymatic activity
To be Published
6KOL
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BU of 6kol by Molmil
Crystal structure of auracyanin from photosynthetic bacterium Roseiflexus castenholzii
Descriptor: Blue (Type 1) copper domain protein, CHLORIDE ION, COPPER (II) ION
Authors:Wang, C, Zhang, C.Y, Min, Z.Z, Xin, Y.Y, Xu, X.L.
Deposit date:2019-08-12
Release date:2020-01-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.211 Å)
Cite:Structural basis underlying the electron transfer features of a blue copper protein auracyanin from the photosynthetic bacterium Roseiflexus castenholzii.
Photosyn. Res., 143, 2020
6L9S
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BU of 6l9s by Molmil
Crystal structure of Na-dithionite reduced auracyanin from photosynthetic bacterium Roseiflexus castenholzii
Descriptor: Blue (Type 1) copper domain protein, COPPER (I) ION
Authors:Wang, C, Zhang, C.Y, Min, Z.Z, Xu, X.L.
Deposit date:2019-11-10
Release date:2020-01-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis underlying the electron transfer features of a blue copper protein auracyanin from the photosynthetic bacterium Roseiflexus castenholzii.
Photosyn. Res., 143, 2020
5Y5W
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BU of 5y5w by Molmil
Crystal structure of human Spindlin1 in complex with a histone H4K20(me3) peptide
Descriptor: Histone peptide H4K20(me3), Spindlin-1
Authors:Wang, C, Zang, J.
Deposit date:2017-08-10
Release date:2017-10-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Spindlin-1 recognizes methylations of K20 and R23 of histone H4 tail
FEBS Lett., 592, 2018
7WN0
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BU of 7wn0 by Molmil
Structure of PfENT1(Y190A) in complex with nanobody 19
Descriptor: Equilibrative nucleoside/nucleobase transporter, nanobody19
Authors:Wang, C, Deng, D, Ren, R.B, Yu, L.Y.
Deposit date:2022-01-17
Release date:2023-02-01
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1.
Nat Commun, 14, 2023
6JUI
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BU of 6jui by Molmil
The atypical Myb-like protein Cdc5 contains two distinct nucleic acid-binding surfaces
Descriptor: Pre-mRNA-splicing factor CEF1
Authors:Wang, C, Li, G, Li, M, Yang, J, Liu, J.
Deposit date:2019-04-14
Release date:2020-02-19
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:Two distinct nucleic acid binding surfaces of Cdc5 regulate development.
Biochem.J., 476, 2019
7YDQ
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BU of 7ydq by Molmil
Structure of PfNT1(Y190A)-GFP in complex with GSK4
Descriptor: 5-methyl-N-[2-(2-oxidanylideneazepan-1-yl)ethyl]-2-phenyl-1,3-oxazole-4-carboxamide, Nucleoside transporter 1,Green fluorescent protein
Authors:Wang, C, Yu, L.Y, Li, J.L, Ren, R.B, Deng, D.
Deposit date:2022-07-04
Release date:2023-04-26
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (4.04 Å)
Cite:Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1.
Nat Commun, 14, 2023
7WN1
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BU of 7wn1 by Molmil
Structure of PfNT1(Y190A) in complex with nanobody 48 and inosine
Descriptor: Equilibrative nucleoside/nucleobase transporter, INOSINE, nanobody48
Authors:Wang, C, Deng, D, Ren, R.B, Yu, L.Y.
Deposit date:2022-01-17
Release date:2023-02-01
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1.
Nat Commun, 14, 2023
7ZEA
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BU of 7zea by Molmil
Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum with bound inhibitor O-benzylhydroxylamine
Descriptor: Aspartate carbamoyltransferase, O-benzylhydroxylamine, SODIUM ION, ...
Authors:Wang, C, Zhang, B.
Deposit date:2022-03-30
Release date:2022-08-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.448 Å)
Cite:Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials.
J.Am.Chem.Soc., 144, 2022
7ZCZ
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BU of 7zcz by Molmil
Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum with bound inhibitor 1-(4-chlorophenyl)methanamine
Descriptor: 1-(4-CHLOROPHENYL)METHANAMINE, Aspartate carbamoyltransferase, SODIUM ION, ...
Authors:Wang, C, Zhang, B.
Deposit date:2022-03-29
Release date:2022-08-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials.
J.Am.Chem.Soc., 144, 2022
7YEN
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BU of 7yen by Molmil
Crystal structure of the Keap1 Kelch domain in complex with Caffeic acid
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAFFEIC ACID, CALCIUM ION, ...
Authors:Wang, C, Jiang, L.
Deposit date:2022-07-06
Release date:2023-07-12
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the Keap1 Kelch domain complexed with Caffeic acid
To Be Published
5YVN
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BU of 5yvn by Molmil
Human Glutathione Transferase Omega1
Descriptor: ACETATE ION, GLUTATHIONE, Glutathione S-transferase omega-1, ...
Authors:Saisawang, C, Ketterman, A, Wongsantichon, J.
Deposit date:2017-11-27
Release date:2018-11-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Glutathione transferase Omega 1-1 (GSTO1-1) modulates Akt and MEK1/2 signaling in human neuroblastoma cell SH-SY5Y.
Proteins, 87, 2019
5YVO
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BU of 5yvo by Molmil
Human Glutathione Transferase Omega1 covalently bound to ML175 inhibitor
Descriptor: ACETATE ION, Glutathione S-transferase omega-1, N-{3-[(2-chloro-acetyl)-(4-nitro-phenyl)-amino]-propyl}-2,2,2-trifluoro-acetamide, ...
Authors:Saisawang, C, Ketterman, A, Wongsantichon, J.
Deposit date:2017-11-27
Release date:2018-11-28
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Glutathione transferase Omega 1-1 (GSTO1-1) modulates Akt and MEK1/2 signaling in human neuroblastoma cell SH-SY5Y.
Proteins, 87, 2019
6RJK
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BU of 6rjk by Molmil
Structure of virulence factor SghA from Agrobacterium tumefaciens
Descriptor: Beta-glucosidase
Authors:Ye, F.Z, Wang, C, Chang, C.Q, Zhang, L.H, Gao, Y.G.
Deposit date:2019-04-27
Release date:2019-10-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.922 Å)
Cite:Agrobacteria reprogram virulence gene expression by controlled release of host-conjugated signals.
Proc.Natl.Acad.Sci.USA, 116, 2019
6RK2
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BU of 6rk2 by Molmil
Complex structure of virulence factor SghA mutant with its substrate SAG
Descriptor: 2-(alpha-L-altropyranosyloxy)benzoic acid, Beta-glucosidase
Authors:Ye, F.Z, Wang, C, Chang, C.Q, Zhang, L.H, Gao, Y.G.
Deposit date:2019-04-30
Release date:2019-10-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Agrobacteria reprogram virulence gene expression by controlled release of host-conjugated signals.
Proc.Natl.Acad.Sci.USA, 116, 2019
6X9Q
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BU of 6x9q by Molmil
Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B3 (TTC-B3) containing an mRNA with a 27 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Ebright, R.H, Wang, C, Su, M.
Deposit date:2020-06-03
Release date:2020-09-02
Last modified:2020-09-23
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
6XII
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BU of 6xii by Molmil
Escherichia coli transcription-translation complex B (TTC-B) containing an 24 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Su, M, Ebright, R.H.
Deposit date:2020-06-20
Release date:2020-09-02
Last modified:2020-09-23
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
6XQN
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BU of 6xqn by Molmil
Structure of a mitochondrial calcium uniporter holocomplex (MICU1, MICU2, MCU, EMRE) in low Ca2+
Descriptor: CALCIUM ION, Calcium uniporter protein, Calcium uptake protein 1, ...
Authors:Long, S.B, Wang, C, Baradaran, R, Jacewicz, A, Delgado, B.
Deposit date:2020-07-09
Release date:2020-07-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structures reveal gatekeeping of the mitochondrial Ca 2+ uniporter by MICU1-MICU2.
Elife, 9, 2020
6X6T
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BU of 6x6t by Molmil
Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B1 (TTC-B1) containing an mRNA with a 24 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Ebright, R.H, Wang, C, Su, M.
Deposit date:2020-05-29
Release date:2020-09-02
Last modified:2020-09-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020
6XQO
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BU of 6xqo by Molmil
Structure of the human MICU1-MICU2 heterodimer, calcium bound, in association with a lipid nanodisc
Descriptor: CALCIUM ION, Calcium uptake protein 1, mitochondrial, ...
Authors:Long, S.B, Wang, C, Baradaran, R, Jacewicz, A, Delgado, B.
Deposit date:2020-07-09
Release date:2020-07-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structures reveal gatekeeping of the mitochondrial Ca 2+ uniporter by MICU1-MICU2.
Elife, 9, 2020
6XIJ
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BU of 6xij by Molmil
Escherichia coli transcription-translation complex A (TTC-A) containing an 24 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
Authors:Molodtsov, V, Wang, C, Su, M, Ebright, R.H.
Deposit date:2020-06-20
Release date:2020-09-02
Last modified:2020-09-23
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Structural basis of transcription-translation coupling.
Science, 369, 2020

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