8EAR
| Structure of the full-length IP3R1 channel determined in the presence of Calcium/IP3/ATP | Descriptor: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... | Authors: | Fan, G, Baker, M.R, Terry, L.E, Arige, V, Chen, M, Seryshev, A.B, Baker, M.L, Ludtke, S.J, Yule, D.I, Serysheva, I.I. | Deposit date: | 2022-08-29 | Release date: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Conformational motions and ligand-binding underlying gating and regulation in IP 3 R channel. Nat Commun, 13, 2022
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8EAQ
| Structure of the full-length IP3R1 channel determined at high Ca2+ | Descriptor: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, CALCIUM ION, Inositol 1,4,5-trisphosphate receptor type 1, ... | Authors: | Fan, G, Baker, M.R, Terry, L.E, Arige, V, Chen, M, Seryshev, A.B, Baker, M.L, Ludtke, S.J, Yule, D.I, Serysheva, I.I. | Deposit date: | 2022-08-29 | Release date: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Conformational motions and ligand-binding underlying gating and regulation in IP 3 R channel. Nat Commun, 13, 2022
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3JBB
| Characterization of red-shifted phycobiliprotein complexes isolated from the chlorophyll f-containing cyanobacterium Halomicronema hongdechloris | Descriptor: | PHYCOCYANOBILIN, SULFATE ION, allophycocyanin beta chain, ... | Authors: | Li, Y, Lin, Y, Garvey, C, Birch, D, Corkery, R.W, Loughlin, P.C, Scheer, H, Willows, R.D, Chen, M. | Deposit date: | 2015-08-26 | Release date: | 2015-11-11 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (26 Å) | Cite: | Characterization of red-shifted phycobilisomes isolated from the chlorophyll f-containing cyanobacterium Halomicronema hongdechloris. Biochim.Biophys.Acta, 1857, 2015
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3IXT
| Crystal Structure of Motavizumab Fab Bound to Peptide Epitope | Descriptor: | 1,2-ETHANEDIOL, Fusion glycoprotein F1, Motavizumab Fab heavy chain, ... | Authors: | McLellan, J.S, Chen, M, Kim, A, Yang, Y, Graham, B.S, Kwong, P.D. | Deposit date: | 2009-09-04 | Release date: | 2010-01-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural basis of respiratory syncytial virus neutralization by motavizumab. Nat.Struct.Mol.Biol., 17, 2010
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6LTR
| Crystal structure of Cas12i2 ternary complex with single Mg2+ bound in catalytic pocket | Descriptor: | 1,2-ETHANEDIOL, Cas12i2, DNA (35-MER), ... | Authors: | Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y. | Deposit date: | 2020-01-23 | Release date: | 2020-10-28 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2. Nat Commun, 11, 2020
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6LU0
| Crystal structure of Cas12i2 ternary complex with 12 nt spacer | Descriptor: | Cas12i2, DNA (5'-D(*GP*CP*CP*GP*CP*TP*TP*TP*CP*TP*T)-3'), DNA (5'-D(*GP*CP*TP*TP*GP*CP*TP*CP*TP*GP*TP*TP*GP*AP*AP*AP*GP*CP*GP*GP*C)-3'), ... | Authors: | Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y. | Deposit date: | 2020-01-24 | Release date: | 2020-10-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.22 Å) | Cite: | Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2. Nat Commun, 11, 2020
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6AKM
| Crystal structure of SLMAP-SIKE1 complex | Descriptor: | GLYCEROL, Sarcolemmal membrane-associated protein, Suppressor of IKBKE 1 | Authors: | Ma, J, Chen, M, Zhou, Z.C. | Deposit date: | 2018-09-02 | Release date: | 2019-01-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling. Cell Discov, 5, 2019
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6LTP
| Crystal structure of Cas12i2 binary complex | Descriptor: | Cas12i2, crRNA (56-mer RNA) | Authors: | Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y. | Deposit date: | 2020-01-23 | Release date: | 2020-10-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2. Nat Commun, 11, 2020
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6NE8
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5H6O
| Porphobilinogen deaminase from Vibrio Cholerae | Descriptor: | 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, MAGNESIUM ION, Porphobilinogen deaminase | Authors: | Funamizu, T, Chen, M, Tanaka, Y, Ishimori, K, Uchida, T. | Deposit date: | 2016-11-14 | Release date: | 2017-11-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.702 Å) | Cite: | Porphobilinogen deaminase from Vibrio Cholerae To Be Published
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7Y71
| SARS-CoV-2 spike glycoprotein trimer complexed with Fab fragment of anti-RBD antibody E7 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab E7 heavy chain, ... | Authors: | Chia, W.N, Tan, C.W, Tan, A.W.K, Young, B, Starr, T.N, Lopez, E, Fibriansah, G, Barr, J, Cheng, S, Yeoh, A.Y.Y, Yap, W.C, Lim, B.L, Ng, T.S, Sia, W.R, Zhu, F, Chen, S, Zhang, J, Greaney, A.J, Chen, M, Au, G.G, Paradkar, P, Peiris, M, Chung, A.W, Bloom, J.D, Lye, D, Lok, S.M, Wang, L.F. | Deposit date: | 2022-06-21 | Release date: | 2023-08-02 | Last modified: | 2023-08-09 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor. Sci Adv, 9, 2023
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7Y72
| SARS-CoV-2 spike glycoprotein trimer complexed with Fab fragment of anti-RBD antibody E7 (focused refinement on Fab-RBD interface) | Descriptor: | Fab E7 heavy chain, Fab E7 light chain, Spike glycoprotein | Authors: | Chia, W.N, Tan, C.W, Tan, A.W.K, Young, B, Starr, T.N, Lopez, E, Fibriansah, G, Barr, J, Cheng, S, Yeoh, A.Y.Y, Yap, W.C, Lim, B.L, Ng, T.S, Sia, W.R, Zhu, F, Chen, S, Zhang, J, Greaney, A.J, Chen, M, Au, G.G, Paradkar, P, Peiris, M, Chung, A.W, Bloom, J.D, Lye, D, Lok, S.M, Wang, L.F. | Deposit date: | 2022-06-21 | Release date: | 2023-08-02 | Last modified: | 2023-08-09 | Method: | ELECTRON MICROSCOPY (4.03 Å) | Cite: | Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor. Sci Adv, 9, 2023
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3O41
| Crystal Structure of 101F Fab Bound to 15-mer Peptide Epitope | Descriptor: | Fusion glycoprotein F1, Mouse monoclonal antibody 101F Fab heavy chain, Mouse monoclonal antibody 101F Fab light chain, ... | Authors: | McLellan, J.S, Chen, M, Chang, J.S, Yang, Y, Kim, A, Graham, B.S, Kwong, P.D. | Deposit date: | 2010-07-26 | Release date: | 2010-10-13 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of a Major Antigenic Site on the Respiratory Syncytial Virus Fusion Glycoprotein in Complex with Neutralizing Antibody 101F. J.Virol., 84, 2010
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3O45
| Crystal Structure of 101F Fab Bound to 17-mer Peptide Epitope | Descriptor: | Fusion glycoprotein F1, Mouse monoclonal antibody 101F 101F Fab heavy chain, Mouse monoclonal antibody 101F 101F Fab light chain, ... | Authors: | McLellan, J.S, Chen, M, Chang, J.S, Yang, Y, Kim, A, Graham, B.S, Kwong, P.D. | Deposit date: | 2010-07-26 | Release date: | 2010-10-13 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.872 Å) | Cite: | Structure of a Major Antigenic Site on the Respiratory Syncytial Virus Fusion Glycoprotein in Complex with Neutralizing Antibody 101F. J.Virol., 84, 2010
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6AKL
| Crystal structure of Striatin3 in complex with SIKE1 Coiled-coil domain | Descriptor: | Striatin-3, Suppressor of IKBKE 1 | Authors: | Zhou, L, Chen, M, Zhou, Z.C. | Deposit date: | 2018-09-02 | Release date: | 2019-01-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling. Cell Discov, 5, 2019
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6AKK
| Crystal structure of the second Coiled-coil domain of SIKE1 | Descriptor: | GLYCEROL, Suppressor of IKBKE 1 | Authors: | Zhou, L, Chen, M, Zhou, Z.C. | Deposit date: | 2018-09-02 | Release date: | 2019-01-16 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling. Cell Discov, 5, 2019
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7YTF
| Structure of OCPx2 from Nostoc flagelliforme CCNUN1 | Descriptor: | Ketosteroid isomerase-related protein, beta,beta-carotene-4,4'-dione | Authors: | Yang, Y.W, Chen, S.Z, Liu, K, Chen, M, Qiu, B.S. | Deposit date: | 2022-08-14 | Release date: | 2023-06-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Functional specialization of expanded orange carotenoid protein paralogs in subaerial Nostoc species. Plant Physiol., 192, 2023
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7XGW
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7EGV
| Acetolactate Synthase from Trichoderma harzianum with inhibitor harzianic acid | Descriptor: | (2S)-3-methyl-2-[[(2S,4R)-1-methyl-4-[(2E,4E)-octa-2,4-dienoyl]-3,5-bis(oxidanylidene)pyrrolidin-2-yl]methyl]-2-oxidanyl-butanoic acid, 1,2-ETHANEDIOL, 2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, ... | Authors: | Zang, X, Xie, L, Chen, M, Tang, Y, Zhou, J. | Deposit date: | 2021-03-26 | Release date: | 2021-06-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Harzianic Acid from Trichoderma afroharzianum Is a Natural Product Inhibitor of Acetohydroxyacid Synthase. J.Am.Chem.Soc., 2021
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7D7E
| Structure of PKD1L3-CTD/PKD2L1 in apo state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Polycystic kidney disease 2-like 1 protein, ... | Authors: | Su, Q, Chen, M, Li, B, Wang, Y, Jing, D, Zhan, X, Yu, Y, Shi, Y. | Deposit date: | 2020-10-03 | Release date: | 2021-08-25 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis for Ca 2+ activation of the heteromeric PKD1L3/PKD2L1 channel. Nat Commun, 12, 2021
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6L30
| Crystal structure of the epithelial cell transforming 2 (ECT2) | Descriptor: | Protein ECT2 | Authors: | Chen, Z.C, Chen, M.R, Pan, H, Sun, L.F, Shi, P. | Deposit date: | 2019-10-07 | Release date: | 2020-01-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure and regulation of human epithelial cell transforming 2 protein. Proc.Natl.Acad.Sci.USA, 117, 2020
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5BV9
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5VHD
| DHX36 with an N-terminal truncation bound to ADP-AlF4 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DEAH (Asp-Glu-Ala-His) box polypeptide 36, TETRAFLUOROALUMINATE ION | Authors: | Chen, M, Ferre-D'Amare, A. | Deposit date: | 2017-04-13 | Release date: | 2018-06-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36. Nature, 558, 2018
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5VHA
| DHX36 with an N-terminal truncation | Descriptor: | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | Authors: | Chen, M, Ferre-D'Amare, A. | Deposit date: | 2017-04-12 | Release date: | 2018-06-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.227 Å) | Cite: | Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36. Nature, 558, 2018
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5VHC
| DHX36 with an N-terminal truncation bound to ADP-BeF3 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DEAH (Asp-Glu-Ala-His) box polypeptide 36, ... | Authors: | Chen, M, Ferre-D'Amare, A. | Deposit date: | 2017-04-12 | Release date: | 2018-06-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36. Nature, 558, 2018
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