5VLI
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![BU of 5vli by Molmil](/molmil-images/mine/5vli) | Computationally designed inhibitor peptide HB1.6928.2.3 in complex with influenza hemagglutinin (A/PuertoRico/8/1934) | Descriptor: | 2,5,8,11-TETRAOXATRIDECANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Bernard, S.M, Wilson, I.A. | Deposit date: | 2017-04-25 | Release date: | 2017-09-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.799 Å) | Cite: | Massively parallel de novo protein design for targeted therapeutics. Nature, 550, 2017
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5W3Q
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![BU of 5w3q by Molmil](/molmil-images/mine/5w3q) | L28F E.coli DHFR in complex with NADPH | Descriptor: | CALCIUM ION, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Oyen, D, Wright, P.E, Wilson, I.A. | Deposit date: | 2017-06-08 | Release date: | 2017-08-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.401 Å) | Cite: | Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate Reductase Using NMR Relaxation Dispersion. J. Am. Chem. Soc., 139, 2017
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5VJL
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![BU of 5vjl by Molmil](/molmil-images/mine/5vjl) | Crystal structure of H7 hemagglutinin mutant (V186K, K193T, G228S) from the influenza virus A/Shanghai/2/2013 (H7N9) with LSTc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ... | Authors: | Zhu, X, Wilson, I.A. | Deposit date: | 2017-04-19 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.597 Å) | Cite: | Three mutations switch H7N9 influenza to human-type receptor specificity. PLoS Pathog., 13, 2017
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5VTW
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1SJ5
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![BU of 1sj5 by Molmil](/molmil-images/mine/1sj5) | Crystal structure of a duf151 family protein (tm0160) from thermotoga maritima at 2.8 A resolution | Descriptor: | conserved hypothetical protein TM0160 | Authors: | Spraggon, G, Panatazatos, D, Klock, H.E, Wilson, I.A, Woods Jr, V.L, Lesley, S.A, Joint Center for Structural Genomics (JCSG) | Deposit date: | 2004-03-02 | Release date: | 2005-03-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | On the use of DXMS to produce more crystallizable proteins: structures of the T. maritima proteins TM0160 and TM1171. Protein Sci., 13, 2004
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1TFH
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![BU of 1tfh by Molmil](/molmil-images/mine/1tfh) | EXTRACELLULAR DOMAIN OF HUMAN TISSUE FACTOR | Descriptor: | HUMAN TISSUE FACTOR | Authors: | Huang, M, Syed, R, Stura, E.A, Stone, M.J, Stefanko, R.S, Ruf, W, Edgington, T.S, Wilson, I.A. | Deposit date: | 1997-04-10 | Release date: | 1998-02-25 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex. J.Mol.Biol., 275, 1998
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5WKZ
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![BU of 5wkz by Molmil](/molmil-images/mine/5wkz) | VH1-69 germline antibody predicted from CR6261 | Descriptor: | Immunoglobulin heavy variable 1-69D,IgG H chain, Lambda-chain (AA -20 to 215), SULFATE ION | Authors: | Lang, S, Lee, P.S. | Deposit date: | 2017-07-25 | Release date: | 2018-08-01 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Anti-idiotypic antibody K1-18 engages VH1-69 precursor and affinity-matured, anti-stem antibodies through mimicry of the HA stem To Be Published
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1HTM
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![BU of 1htm by Molmil](/molmil-images/mine/1htm) | STRUCTURE OF INFLUENZA HAEMAGGLUTININ AT THE PH OF MEMBRANE FUSION | Descriptor: | HEMAGGLUTININ HA1 CHAIN, HEMAGGLUTININ HA2 CHAIN | Authors: | Bullough, P.A, Hughson, F.M, Skehel, J.J, Wiley, D.C. | Deposit date: | 1994-11-02 | Release date: | 1995-02-14 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of influenza haemagglutinin at the pH of membrane fusion. Nature, 371, 1994
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4OCS
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![BU of 4ocs by Molmil](/molmil-images/mine/4ocs) | Crystal structure of human Fab CAP256-VRC26.10, a potent V1V2-directed HIV-1 neutralizing antibody | Descriptor: | CAP256-VRC26.10 heavy chain, CAP256-VRC26.10 light chain | Authors: | Gorman, J, Doria-Rose, N.A, Schramm, C.A, Moore, P.L, Mascola, J.R, Shapiro, L, Morris, L, Kwong, P.D. | Deposit date: | 2014-01-09 | Release date: | 2014-02-26 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature, 509, 2014
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5XRQ
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![BU of 5xrq by Molmil](/molmil-images/mine/5xrq) | Crystal structure of human monoclonal antibody H3v-47 | Descriptor: | Fab H3v-47 heavy chain, Fab H3v-47 light chain | Authors: | Zhang, H, Willson, I.A. | Deposit date: | 2017-06-09 | Release date: | 2018-07-25 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA. Nat Commun, 9, 2018
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1VR3
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1VRM
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1VQ0
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2XMS
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![BU of 2xms by Molmil](/molmil-images/mine/2xms) | Crystal structure of human NDRG2 protein provides insight into its role as a tumor suppressor | Descriptor: | CHLORIDE ION, IMIDAZOLE, PROTEIN NDRG2 | Authors: | Hwang, J, Kim, Y, Lee, H, Kim, M.H. | Deposit date: | 2010-07-29 | Release date: | 2011-01-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal Structure of Human Ndrg2 Protein Provides Insight Into its Role as a Tumor Suppressor. J.Biol.Chem., 286, 2011
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2XMR
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![BU of 2xmr by Molmil](/molmil-images/mine/2xmr) | Crystal structure of human NDRG2 protein provides insight into its role as a tumor suppressor | Descriptor: | ACETATE ION, CALCIUM ION, GLYCEROL, ... | Authors: | Hwang, J, Kim, Y, Lee, H, Kim, M.H. | Deposit date: | 2010-07-29 | Release date: | 2011-01-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Human Ndrg2 Protein Provides Insight Into its Role as a Tumor Suppressor. J.Biol.Chem., 286, 2011
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8SIT
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8SIS
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8SIR
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8SIQ
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3U46
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![BU of 3u46 by Molmil](/molmil-images/mine/3u46) | CH04H/CH02L P212121 | Descriptor: | CH02 Light chain Fab, CH04 Heavy chain Fab | Authors: | Louder, R, Pancera, M, McLellan, J.S, Kwong, P.D. | Deposit date: | 2011-10-07 | Release date: | 2011-11-30 | Last modified: | 2011-12-21 | Method: | X-RAY DIFFRACTION (2.906 Å) | Cite: | Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature, 480, 2011
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3UFI
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3KW0
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2G36
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2FO4
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2GAZ
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![BU of 2gaz by Molmil](/molmil-images/mine/2gaz) | Mycobacterial lipoglycan presentation by CD1d | Descriptor: | (2R)-3-[(HYDROXY{[(2R,3R,5S,6R)-3,4,5-TRIHYDROXY-2,6-BIS(ALPHA-D-MANNOPYRANOSYLOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]PROPAN E-1,2-DIYL DIHEXADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, T-cell surface glycoprotein CD1d1, ... | Authors: | Zajonc, D.M. | Deposit date: | 2006-03-09 | Release date: | 2006-09-26 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Structural characterization of mycobacterial phosphatidylinositol mannoside binding to mouse CD1d. J.Immunol., 177, 2006
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