6PI9
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![BU of 6pi9 by Molmil](/molmil-images/mine/6pi9) | Crystal structure of 16S rRNA methyltransferase RmtF in complex with S-Adenosyl-L-homocysteine | Descriptor: | 16S rRNA (guanine(1405)-N(7))-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Stogios, P.J, Kim, Y, Evdokimova, E, Di Leo, R, Semper, C, Savchenko, A, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-06-26 | Release date: | 2019-07-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of 16S rRNA methylase RmtF in complex with S-Adenosyl-L-homocysteine To be Published
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6PTA
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![BU of 6pta by Molmil](/molmil-images/mine/6pta) | Crystal structure of the ARF family small GTPase ARF1 from Candida albicans in complex with GDP | Descriptor: | ADP-ribosylation factor, GUANOSINE-5'-DIPHOSPHATE | Authors: | Stogios, P.J, Evdokimova, E, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-07-15 | Release date: | 2019-07-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the ARF family small GTPase ARF1 from Candida albicans in complex with GDP To Be Published
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7KES
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![BU of 7kes by Molmil](/molmil-images/mine/7kes) | Crystal structure of meta-AAC0038, an environmental aminoglycoside resistance enzyme, mutant H168A in complex with apramycin and CoA | Descriptor: | APRAMYCIN, Aminoglycoside N(3)-acetyltransferase, CHLORIDE ION, ... | Authors: | Stogios, P.J, Skarina, T, Michalska, K, Xu, Z, Yim, V, Savchenko, A, Joachimiak, A, Satchell, K.J, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-10-12 | Release date: | 2020-10-21 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family. Commun Biol, 5, 2022
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7KAG
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![BU of 7kag by Molmil](/molmil-images/mine/7kag) | Crystal structure of the ubiquitin-like domain 1 (Ubl1) of Nsp3 from SARS-CoV-2 | Descriptor: | 1,2-ETHANEDIOL, Non-structural protein 3, SULFATE ION | Authors: | Stogios, P.J, Skarina, T, Chang, C, Kim, Y, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-09-30 | Release date: | 2020-10-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | Crystal structure of the ubiquitin-like domain 1 (Ubl1) of Nsp3 from SARS-CoV-2 To Be Published
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7JM1
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![BU of 7jm1 by Molmil](/molmil-images/mine/7jm1) | Crystal structure of aminoglycoside resistance enzyme ApmA, complex with acetyl-CoA | Descriptor: | ACETYL COENZYME *A, Aminocyclitol acetyltransferase ApmA | Authors: | Stogios, P.J, Evdokimova, E, Di Leo, R, Bordeleau, E, Wright, G.D, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-07-30 | Release date: | 2020-09-16 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Crystal structure of aminoglycoside resistance enzyme ApmA, complex with acetyl-CoA To Be Published
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7JM2
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![BU of 7jm2 by Molmil](/molmil-images/mine/7jm2) | Crystal structure of aminoglycoside resistance enzyme ApmA, complex with apramycin | Descriptor: | APRAMYCIN, Aminocyclitol acetyltransferase ApmA, CHLORIDE ION | Authors: | Stogios, P.J, Evdokimova, E, Di Leo, R, Bordeleau, E, Wright, G.D, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-07-30 | Release date: | 2020-09-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of aminoglycoside resistance enzyme ApmA, complex with apramycin To Be Published
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7JM0
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![BU of 7jm0 by Molmil](/molmil-images/mine/7jm0) | Crystal structure of aminoglycoside resistance enzyme ApmA, apoenzyme | Descriptor: | Aminocyclitol acetyltransferase ApmA, SULFATE ION | Authors: | Stogios, P.J, Evdokimova, E, Di Leo, R, Bordeleau, E, Wright, G.D, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-07-30 | Release date: | 2020-09-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Crystal structure of aminoglycoside resistance enzyme ApmA, apoenzyme To Be Published
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7KZW
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![BU of 7kzw by Molmil](/molmil-images/mine/7kzw) | Crystal structure of FTT_1639c from Francisella tularensis str. tularensis SCHU S4 | Descriptor: | CHLORIDE ION, FTT_1639c | Authors: | Stogios, P.J, Skarina, T, Osipiuk, J, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-12-10 | Release date: | 2020-12-30 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Crystal structure of FTT_1639c from Francisella tularensis str. tularensis SCHU S4 To Be Published
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7MWA
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![BU of 7mwa by Molmil](/molmil-images/mine/7mwa) | Crystal structure of 2-octaprenyl-6-methoxyphenol hydroxylase UbiH from Acinetobacter baumannii, apoenzyme | Descriptor: | 1,2-ETHANEDIOL, 2-polyprenyl-6-methoxyphenol 4-hydroxylase, CHLORIDE ION, ... | Authors: | Stogios, P.J, Evdokimova, E, Endres, M, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2021-05-16 | Release date: | 2021-05-26 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | UbiH from Acinetobacter baumannii To Be Published
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7LAP
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![BU of 7lap by Molmil](/molmil-images/mine/7lap) | Crystal structure of aminoglycoside acetyltransferase AAC(3)-Xa | Descriptor: | Aminoglycoside N(3)-acetyltransferase, CHLORIDE ION, D(-)-TARTARIC ACID, ... | Authors: | Stogios, P.J, Skarina, T, Kim, Y, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2021-01-06 | Release date: | 2021-02-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family. Commun Biol, 5, 2022
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7LAO
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![BU of 7lao by Molmil](/molmil-images/mine/7lao) | Crystal structure of aminoglycoside acetyltransferase AAC(3)-IIb | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Aminoglycoside N(3)-acetyltransferase III, MAGNESIUM ION | Authors: | Stogios, P.J, Evdokimova, E, Osipiuk, J, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2021-01-06 | Release date: | 2021-01-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family. Commun Biol, 5, 2022
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7LGO
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![BU of 7lgo by Molmil](/molmil-images/mine/7lgo) | Crystal structure of the nucleic acid binding domain (NAB) of Nsp3 from SARS-CoV-2 | Descriptor: | Non-structural protein 3 | Authors: | Stogios, P.J, Skarina, T, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2021-01-20 | Release date: | 2021-01-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal structure of the nucleic acid binding domain (NAB) of Nsp3 from SARS-CoV-2 To Be Published
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5DT9
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![BU of 5dt9 by Molmil](/molmil-images/mine/5dt9) | Crystal structure of a putative D-Erythronate-4-Phosphate Dehydrogenase from Vibrio cholerae | Descriptor: | CHLORIDE ION, Erythronate-4-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Stogios, P.J, Skarina, T, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2015-09-17 | Release date: | 2015-09-30 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.663 Å) | Cite: | Crystal structure of a putative D-Erythronate-4-Phosphate Dehydrogenase from Vibrio cholerae To Be Published
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4WH5
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![BU of 4wh5 by Molmil](/molmil-images/mine/4wh5) | Crystal structure of lincosamide antibiotic adenylyltransferase LnuA, lincomycin-bound | Descriptor: | CHLORIDE ION, LINCOMYCIN, Lincosamide resistance protein, ... | Authors: | Stogios, P.J, Dong, A, Minasov, G, Evdokimova, E, Egorova, O, Kudritska, M, Yim, O, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2014-09-20 | Release date: | 2014-11-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | CRYSTAL STRUCTURE OF LINCOSAMIDE ANTIBIOTIC ADENYLYLTRANSFERASE LNUA, LINCOMYCIN BOUND To Be Published
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4XCW
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![BU of 4xcw by Molmil](/molmil-images/mine/4xcw) | |
5FBT
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![BU of 5fbt by Molmil](/molmil-images/mine/5fbt) | Crystal structure of rifampin phosphotransferase RPH-Lm from Listeria monocytogenes in complex with rifampin | Descriptor: | CHLORIDE ION, Phosphoenolpyruvate synthase, Rifampin | Authors: | Stogios, P.J, Wawrzak, Z, Skarina, T, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2015-12-14 | Release date: | 2015-12-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.702 Å) | Cite: | Rifampin phosphotransferase is an unusual antibiotic resistance kinase. Nat Commun, 7, 2016
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5FBS
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![BU of 5fbs by Molmil](/molmil-images/mine/5fbs) | Crystal structure of rifampin phosphotransferase RPH-Lm from Listeria monocytogenes in complex with ADP and magnesium | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Phosphoenolpyruvate synthase | Authors: | Stogios, P.J, Wawrzak, Z, Skarina, T, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2015-12-14 | Release date: | 2016-01-13 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Rifampin phosphotransferase is an unusual antibiotic resistance kinase. Nat Commun, 7, 2016
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4XV0
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![BU of 4xv0 by Molmil](/molmil-images/mine/4xv0) | Crystal structure of an endo-beta-1,4-xylanase (glycoside hydrolase family 10/GH10) enzyme from Trichoderma reesei | Descriptor: | Beta-xylanase, CHLORIDE ION, GLYCEROL, ... | Authors: | Stogios, P.J, Xu, X, Cui, H, Savchenko, A. | Deposit date: | 2015-01-26 | Release date: | 2015-02-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.9697 Å) | Cite: | Crystal structure of an endo-beta-1,4-xylanase (glycoside hydrolase family 10/GH10) enzyme from Trichoderma reesei To Be Published
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4XVH
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![BU of 4xvh by Molmil](/molmil-images/mine/4xvh) | Crystal structure of a Corynascus thermopiles (Myceliophthora fergusii) carbohydrate esterase family 2 (CE2) enzyme plus carbohydrate binding domain (CBD) | Descriptor: | 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, Carbohydrate esterase family 2 (CE2), GLYCEROL | Authors: | Stogios, P.J, Dong, A, Xu, X, Cui, H, Savchenko, A. | Deposit date: | 2015-01-27 | Release date: | 2015-02-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.9449 Å) | Cite: | Crystal structure of a Corynascus thermopiles carbohydrate esterase family 2 (CE2) enzyme plus carbohydrate binding domain (CBD) To Be Published
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4XX6
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![BU of 4xx6 by Molmil](/molmil-images/mine/4xx6) | Crystal structure of a glycosylated endo-beta-1,4-xylanase (glycoside hydrolase family 10/GH10) enzyme from Gloeophyllum trabeum | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-xylanase, ... | Authors: | Stogios, P.J, Nocek, B, Xu, X, Cui, H, Lowden, M, Savchenko, A. | Deposit date: | 2015-01-29 | Release date: | 2015-02-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of a glycosylated endo-beta-1,4-xylanase (glycoside hydrolase family 10/GH10) enzyme from Gloeophyllum trabeum. To Be Published
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4XUV
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![BU of 4xuv by Molmil](/molmil-images/mine/4xuv) | Crystal structure of a glycoside hydrolase family 105 (GH105) enzyme from Thielavia terrestris | Descriptor: | GLYCEROL, Glycoside hydrolase family 105 protein | Authors: | Stogios, P.J, Xu, X, Cui, H, Yim, V, Savchenko, A. | Deposit date: | 2015-01-26 | Release date: | 2015-02-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.0496 Å) | Cite: | Crystal structure of a glycoside hydrolase family 105 (GH105) enzyme from Thielavia terrestris To Be Published
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5FBU
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![BU of 5fbu by Molmil](/molmil-images/mine/5fbu) | Crystal structure of rifampin phosphotransferase RPH-Lm from Listeria monocytogenes in complex with rifampin-phosphate | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Phosphoenolpyruvate synthase, ... | Authors: | Stogios, P.J, Wawrzak, Z, Skarina, T, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2015-12-14 | Release date: | 2015-12-30 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Rifampin phosphotransferase is an unusual antibiotic resistance kinase. Nat Commun, 7, 2016
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4XUY
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![BU of 4xuy by Molmil](/molmil-images/mine/4xuy) | Crystal structure of an endo-beta-1,4-xylanase (glycoside hydrolase family 10/GH10) enzyme from Aspergillus niger | Descriptor: | GLYCEROL, Probable endo-1,4-beta-xylanase C, SULFATE ION | Authors: | Stogios, P.J, Dong, A, Xu, X, Cui, H, Savchenko, A. | Deposit date: | 2015-01-26 | Release date: | 2015-02-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.0027 Å) | Cite: | Crystal structure of an endo-beta-1,4-xylanase (glycoside hydrolase family 10/GH10) enzyme from Aspergillus niger To Be Published
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4YFJ
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![BU of 4yfj by Molmil](/molmil-images/mine/4yfj) | Crystal structure of aminoglycoside acetyltransferase AAC(3)-Ib | Descriptor: | Aminoglycoside 3'-N-acetyltransferase, SULFATE ION | Authors: | Stogios, P.J, Xu, Z, Evdokimova, E, Yim, V, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2015-02-25 | Release date: | 2015-03-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of aminoglycoside acetyltransferase AAC(3)-Ib To Be Published
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3TYK
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![BU of 3tyk by Molmil](/molmil-images/mine/3tyk) | Crystal structure of aminoglycoside phosphotransferase APH(4)-Ia | Descriptor: | CHLORIDE ION, HYGROMYCIN B VARIANT, Hygromycin-B 4-O-kinase | Authors: | Stogios, P.J, Shabalin, I.G, Shakya, T, Evdokmova, E, Fan, Y, Chruszcz, M, Minor, W, Wright, G.D, Savchenko, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-09-26 | Release date: | 2011-10-12 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure and function of APH(4)-Ia, a hygromycin B resistance enzyme. J.Biol.Chem., 286, 2011
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