7LAP

Crystal structure of aminoglycoside acetyltransferase AAC(3)-Xa

Summary for 7LAP

Entry DOI	10.2210/pdb7lap/pdb
Descriptor	Aminoglycoside N(3)-acetyltransferase, D(-)-TARTARIC ACID, FORMIC ACID, ... (5 entities in total)
Functional Keywords	aac(3)-xa, resistance, csgid, transferase, center for structural genomics of infectious diseases, national institute of allergy and infectious diseases, niaid
Biological source	Streptomyces griseus
Total number of polymer chains	2
Total formula weight	64535.18
Authors	Stogios, P.J.,Skarina, T.,Kim, Y.,Di Leo, R.,Savchenko, A.,Joachimiak, A.,Satchell, K.J.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2021-01-06, release date: 2021-02-03, Last modification date: 2023-10-18)
Primary citation	Stogios, P.J.,Bordeleau, E.,Xu, Z.,Skarina, T.,Evdokimova, E.,Chou, S.,Diorio-Toth, L.,D'Souza, A.W.,Patel, S.,Dantas, G.,Wright, G.D.,Savchenko, A. Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family. Commun Biol, 5:263-263, 2022 Cited by PubMed: 35338238 DOI: 10.1038/s42003-022-03219-w PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.04 Å)

Structure validation