4WH5
Crystal structure of lincosamide antibiotic adenylyltransferase LnuA, lincomycin-bound
Replaces: 4E8JSummary for 4WH5
Entry DOI | 10.2210/pdb4wh5/pdb |
Related | 4E8J 4FO1 |
Descriptor | Lincosamide resistance protein, CHLORIDE ION, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | structural genomics, antibiotic resistance, center for structural genomics of infectious diseases (csgid), alpha+beta structure, aminoglycoside-2''-adenylyltransferase superfamily, nucleotidyltransferase superfamily, transferase, lincosamide adenylyltransferase, lincosamide antibiotics, lincomycin, clindamycin, adenosine triphosphate, intracellular, transferase-antibiotic complex, transferase/antibiotic |
Biological source | Staphylococcus haemolyticus |
Total number of polymer chains | 2 |
Total formula weight | 39567.54 |
Authors | Stogios, P.J.,Dong, A.,Minasov, G.,Evdokimova, E.,Egorova, O.,Kudritska, M.,Yim, O.,Courvalin, P.,Savchenko, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2014-09-20, release date: 2014-11-05, Last modification date: 2023-11-15) |
Primary citation | Stogios, P.J. CRYSTAL STRUCTURE OF LINCOSAMIDE ANTIBIOTIC ADENYLYLTRANSFERASE LNUA, LINCOMYCIN BOUND To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.82 Å) |
Structure validation
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