4WH5

Crystal structure of lincosamide antibiotic adenylyltransferase LnuA, lincomycin-bound

Replaces:  4E8J

Summary for 4WH5

• Entry DOI: 10.2210/pdb4wh5/pdb
• Related: 4E8J 4FO1
• Descriptor: Lincosamide resistance protein, CHLORIDE ION, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: structural genomics, antibiotic resistance, center for structural genomics of infectious diseases (csgid), alpha+beta structure, aminoglycoside-2''-adenylyltransferase superfamily, nucleotidyltransferase superfamily, transferase, lincosamide adenylyltransferase, lincosamide antibiotics, lincomycin, clindamycin, adenosine triphosphate, intracellular, transferase-antibiotic complex, transferase/antibiotic
• Biological source: Staphylococcus haemolyticus
• Total number of polymer chains: 2
• Total formula weight: 39567.54

Authors

Stogios, P.J.,Dong, A.,Minasov, G.,Evdokimova, E.,Egorova, O.,Kudritska, M.,Yim, O.,Courvalin, P.,Savchenko, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2014-09-20, release date: 2014-11-05, Last modification date: 2023-11-15)

• Primary citation: Stogios, P.J.; CRYSTAL STRUCTURE OF LINCOSAMIDE ANTIBIOTIC ADENYLYLTRANSFERASE LNUA, LINCOMYCIN BOUND; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.82 Å)