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4RYX
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BU of 4ryx by Molmil
Crystal structure of RPE65 in complex with emixustat and palmitate, P6522 crystal form
Descriptor: (1R)-3-amino-1-[3-(cyclohexylmethoxy)phenyl]propan-1-ol, (4S)-2-METHYL-2,4-PENTANEDIOL, FE (II) ION, ...
Authors:Kiser, P.D, Palczewski, K.
Deposit date:2014-12-17
Release date:2015-05-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular pharmacodynamics of emixustat in protection against retinal degeneration.
J.Clin.Invest., 125, 2015
4RYY
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BU of 4ryy by Molmil
Crystal structure of RPE65 in complex with R-emixustat and palmitate
Descriptor: (1R)-3-amino-1-[3-(cyclohexylmethoxy)phenyl]propan-1-ol, FE (II) ION, PALMITIC ACID, ...
Authors:Kiser, P.D, Palczewski, K.
Deposit date:2014-12-17
Release date:2015-05-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular pharmacodynamics of emixustat in protection against retinal degeneration.
J.Clin.Invest., 125, 2015
4RYZ
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BU of 4ryz by Molmil
Crystal structure of RPE65 in complex with S-emixustat and palmitate
Descriptor: (1S)-3-amino-1-[3-(cyclohexylmethoxy)phenyl]propan-1-ol, FE (II) ION, PALMITIC ACID, ...
Authors:Kiser, P.D, Palczewski, K.
Deposit date:2014-12-17
Release date:2015-05-27
Last modified:2021-07-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular pharmacodynamics of emixustat in protection against retinal degeneration.
J.Clin.Invest., 125, 2015
2XVO
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BU of 2xvo by Molmil
SSO1725, a protein involved in the CRISPR/Cas pathway
Descriptor: BETA-MERCAPTOETHANOL, SSO1725, SULFATE ION
Authors:Reeks, J, Liu, H, Naismith, J, White, M, McMahon, S.
Deposit date:2010-10-26
Release date:2010-12-29
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structure and Mechanism of the Cmr Complex for Crispr-Mediated Antiviral Immunity.
Mol.Cell, 45, 2012
3K5V
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BU of 3k5v by Molmil
Structure of Abl kinase in complex with imatinib and GNF-2
Descriptor: 3-(6-{[4-(trifluoromethoxy)phenyl]amino}pyrimidin-4-yl)benzamide, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, CHLORIDE ION, ...
Authors:Cowan-Jacob, S.W, Fendrich, G, Rummel, G, Strauss, A.
Deposit date:2009-10-08
Release date:2010-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors.
Nature, 463, 2010
8FY5
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BU of 8fy5 by Molmil
Human TMEM175-LAMP1 full-length complex
Descriptor: Endosomal/lysosomal potassium channel TMEM175, Lysosome-associated membrane glycoprotein 1
Authors:Zhang, J.Y, Zeng, W.Z, Han, Y, Jiang, Y.X.
Deposit date:2023-01-25
Release date:2023-06-28
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel.
Mol.Cell, 83, 2023
8FYF
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BU of 8fyf by Molmil
Human TMEM175-LAMP1 transmembrane domain only complex
Descriptor: Endosomal/lysosomal potassium channel TMEM175, Lysosome-associated membrane glycoprotein 1
Authors:Zhang, J.Y, Zeng, W.Z, Han, Y, Jiang, Y.X.
Deposit date:2023-01-26
Release date:2023-06-28
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel.
Mol.Cell, 83, 2023
4ZHK
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BU of 4zhk by Molmil
Crystal structure of RPE65 in complex with MB-002
Descriptor: (1R)-1-[3-(cyclohexylmethoxy)phenyl]propane-1,3-diol, (1S)-1-[3-(cyclohexylmethoxy)phenyl]propane-1,3-diol, FE (II) ION, ...
Authors:Kiser, P.D, Palczewski, K.
Deposit date:2015-04-25
Release date:2015-05-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Molecular pharmacodynamics of emixustat in protection against retinal degeneration.
J.Clin.Invest., 125, 2015
6LMR
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BU of 6lmr by Molmil
Solution structure of cold shock domain and ssDNA complex
Descriptor: DNA (5'-D(P*AP*AP*CP*AP*CP*CP*T)-3'), Y-box-binding protein 1
Authors:Fan, J, Yang, D.
Deposit date:2019-12-26
Release date:2020-07-22
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis of DNA binding to human YB-1 cold shock domain regulated by phosphorylation.
Nucleic Acids Res., 48, 2020
4QOZ
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BU of 4qoz by Molmil
Crystal structure of the histone mRNA stem-loop, stem-loop binding protein (phosphorylated), and 3'hExo ternary complex
Descriptor: 3'-5' exoribonuclease 1, Histone RNA hairpin-binding protein, histone mRNA stem-loop
Authors:Tan, D, Tong, L.
Deposit date:2014-06-21
Release date:2014-07-23
Last modified:2014-08-06
Method:X-RAY DIFFRACTION (2.304 Å)
Cite:Molecular mechanisms for the regulation of histone mRNA stem-loop-binding protein by phosphorylation.
Proc.Natl.Acad.Sci.USA, 111, 2014
8HIP
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BU of 8hip by Molmil
dsRNA transporter
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Systemic RNA interference defective protein 1, ZINC ION, ...
Authors:Jiang, D.H, Zhang, J.T.
Deposit date:2022-11-21
Release date:2023-11-29
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:Structural insights into double-stranded RNA recognition and transport by SID-1.
Nat.Struct.Mol.Biol., 2024
8HKE
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BU of 8hke by Molmil
dsRNA transporter
Descriptor: RNA (37-MER), Systemic RNA interference defective protein 1, ZINC ION
Authors:Jiang, D.H, Zhang, J.T.
Deposit date:2022-11-25
Release date:2023-11-29
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Structural insights into double-stranded RNA recognition and transport by SID-1.
Nat.Struct.Mol.Biol., 2024
8EJM
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BU of 8ejm by Molmil
Crystal structure of human DEAH-box helicase DHX15 in complex with SUGP1 G-patch
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DHX15, CHLORIDE ION, ...
Authors:Huang, J, Tong, L.
Deposit date:2022-09-17
Release date:2022-12-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:DHX15 is involved in SUGP1-mediated RNA missplicing by mutant SF3B1 in cancer.
Proc.Natl.Acad.Sci.USA, 119, 2022
6O3S
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BU of 6o3s by Molmil
NMR solution structure of Luffin P1
Descriptor: Ribosome-inactivating protein luffin P1
Authors:Rosengren, K.J, Payne, C.
Deposit date:2019-02-27
Release date:2019-04-24
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:An Ancient Peptide Family Buried within Vicilin Precursors.
Acs Chem.Biol., 14, 2019
6O3Q
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BU of 6o3q by Molmil
NMR solution structure of vicilin-buried peptide-8 (VBP-8)
Descriptor: Vicilin
Authors:Rosengren, K.J, Payne, C.
Deposit date:2019-02-27
Release date:2019-04-24
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:An Ancient Peptide Family Buried within Vicilin Precursors.
Acs Chem.Biol., 14, 2019
4FBZ
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BU of 4fbz by Molmil
Crystal structure of deltarhodopsin from Haloterrigena thermotolerans
Descriptor: (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene, 2,3-DI-PHYTANYL-GLYCEROL, BACTERIORUBERIN, ...
Authors:Kouyama, T.
Deposit date:2012-05-23
Release date:2013-05-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of deltarhodopsin-3 from Haloterrigena thermotolerans
Proteins, 81, 2013
3DIW
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BU of 3diw by Molmil
c-terminal beta-catenin bound TIP-1 structure
Descriptor: Tax1-binding protein 3, decameric peptide form Catenin beta-1
Authors:Shen, Y.
Deposit date:2008-06-21
Release date:2008-10-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis of beta-Catenin Recognition by Tax-interacting Protein-1
J.Mol.Biol., 384, 2008
3DJ3
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BU of 3dj3 by Molmil
Crystal Structure of C-terminal Truncated TIP-1 (6-113)
Descriptor: Tax1-binding protein 3
Authors:Shen, Y.
Deposit date:2008-06-21
Release date:2008-10-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis of beta-Catenin Recognition by Tax-interacting Protein-1
J.Mol.Biol., 384, 2008
8HKQ
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BU of 8hkq by Molmil
ion channel
Descriptor: POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ...
Authors:Jiang, D.H, Zhang, J.T.
Deposit date:2022-11-27
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
8HKK
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BU of 8hkk by Molmil
ion channel
Descriptor: POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ...
Authors:Jiang, D.H, Zhang, J.T.
Deposit date:2022-11-27
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
8HIR
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BU of 8hir by Molmil
potassium channels
Descriptor: POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ...
Authors:Jiang, D.H, Zhang, J.T.
Deposit date:2022-11-21
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
8HKM
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BU of 8hkm by Molmil
ion channel
Descriptor: POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION, ...
Authors:Jiang, D.H, Zhang, J.T.
Deposit date:2022-11-27
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
8HK6
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BU of 8hk6 by Molmil
potassium channel
Descriptor: POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION
Authors:Jiang, D.H, Zhang, J.T.
Deposit date:2022-11-25
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
8HKF
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BU of 8hkf by Molmil
ion channel
Descriptor: POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION
Authors:Jiang, D.H, Zhang, Z.T.
Deposit date:2022-11-25
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
3DJ1
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BU of 3dj1 by Molmil
crystal structure of TIP-1 wild type
Descriptor: SULFATE ION, Tax1-binding protein 3
Authors:Shen, Y.
Deposit date:2008-06-21
Release date:2008-10-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis of beta-Catenin Recognition by Tax-interacting Protein-1
J.Mol.Biol., 384, 2008

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