5KTU
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![BU of 5ktu by Molmil](/molmil-images/mine/5ktu) | Crystal structure of the bromodomain of human CREBBP bound to pyrazolopiperidine scaffold | Descriptor: | 1-(3-phenylazanyl-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridin-5-yl)ethanone, CREB-binding protein, DIMETHYL SULFOXIDE | Authors: | Jayaram, H, Poy, F, Setser, J.W, Bellon, S.F. | Deposit date: | 2016-07-12 | Release date: | 2016-11-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300. J. Med. Chem., 59, 2016
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7DQ7
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![BU of 7dq7 by Molmil](/molmil-images/mine/7dq7) | Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 5F5 | Descriptor: | 5F5 VH, 5F5 VL, Capsid protein VP4, ... | Authors: | Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q. | Deposit date: | 2020-12-22 | Release date: | 2021-05-05 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating. Cell Host Microbe, 29, 2021
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7DQ4
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![BU of 7dq4 by Molmil](/molmil-images/mine/7dq4) | Cryo-EM structure of CAR triggered Coxsackievirus B1 A-particle | Descriptor: | VP2, VP3, Virion protein 1 | Authors: | Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q. | Deposit date: | 2020-12-22 | Release date: | 2021-05-05 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating. Cell Host Microbe, 29, 2021
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7DPZ
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![BU of 7dpz by Molmil](/molmil-images/mine/7dpz) | Cryo-EM structure of Coxsackievirus B1 virion in complex with CAR | Descriptor: | Capsid protein VP4, Coxsackievirus and adenovirus receptor, VP2, ... | Authors: | Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q. | Deposit date: | 2020-12-22 | Release date: | 2021-05-05 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating. Cell Host Microbe, 29, 2021
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7DPG
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![BU of 7dpg by Molmil](/molmil-images/mine/7dpg) | Cryo-EM structure of Coxsackievirus B1 empty particle | Descriptor: | VP2, VP3, Virion protein 1 | Authors: | Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q, Xia, N. | Deposit date: | 2020-12-18 | Release date: | 2021-05-05 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating. Cell Host Microbe, 29, 2021
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7DQ1
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![BU of 7dq1 by Molmil](/molmil-images/mine/7dq1) | Cryo-EM structure of Coxsackievirus B1 virion in complex with CAR at physiological temperature | Descriptor: | Capsid protein VP4, Coxsackievirus and adenovirus receptor, VP2, ... | Authors: | Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q. | Deposit date: | 2020-12-22 | Release date: | 2021-05-05 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating. Cell Host Microbe, 29, 2021
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6LGN
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![BU of 6lgn by Molmil](/molmil-images/mine/6lgn) | The atomic structure of varicella zoster virus C-capsid | Descriptor: | Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ... | Authors: | Li, S, Zheng, Q. | Deposit date: | 2019-12-05 | Release date: | 2020-07-29 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (5.3 Å) | Cite: | Near-atomic cryo-electron microscopy structures of varicella-zoster virus capsids. Nat Microbiol, 5, 2020
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6LGL
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![BU of 6lgl by Molmil](/molmil-images/mine/6lgl) | The atomic structure of varicella-zoster virus A-capsid | Descriptor: | Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ... | Authors: | Zheng, Q, Li, S. | Deposit date: | 2019-12-05 | Release date: | 2020-07-29 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Near-atomic cryo-electron microscopy structures of varicella-zoster virus capsids. Nat Microbiol, 5, 2020
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4FC2
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![BU of 4fc2 by Molmil](/molmil-images/mine/4fc2) | |
7CHO
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![BU of 7cho by Molmil](/molmil-images/mine/7cho) | Crystal structure of SARS-CoV-2 antibody P5A-1D2 with RBD | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P5A-1D2 heavy chain, ... | Authors: | Wang, X, Zhang, L, Ge, J, Wang, R, Zhang, Q. | Deposit date: | 2020-07-06 | Release date: | 2021-05-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.561 Å) | Cite: | Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2. Nat Commun, 12, 2021
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7CHS
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![BU of 7chs by Molmil](/molmil-images/mine/7chs) | Crystal structure of SARS-CoV-2 antibody P22A-1D1 with RBD | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P22A-1D1 heavy chain, ... | Authors: | Wang, X, Zhang, L, Ge, J, Wang, R, Zhang, Q. | Deposit date: | 2020-07-06 | Release date: | 2021-05-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.401 Å) | Cite: | Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2. Nat Commun, 12, 2021
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7CHP
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![BU of 7chp by Molmil](/molmil-images/mine/7chp) | Crystal structure of SARS-CoV-2 antibody P5A-3C8 with RBD | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P5A-3C8 heavy chain, ... | Authors: | Wang, X, Zhang, L, Ge, J, Wang, R, Zhang, Q. | Deposit date: | 2020-07-06 | Release date: | 2021-05-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.357 Å) | Cite: | Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2. Nat Commun, 12, 2021
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7DPF
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![BU of 7dpf by Molmil](/molmil-images/mine/7dpf) | Cryo-EM structure of Coxsackievirus B1 mature virion | Descriptor: | Capsid protein VP4, PALMITIC ACID, VP2, ... | Authors: | Zheng, Q, Li, S. | Deposit date: | 2020-12-18 | Release date: | 2021-05-05 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating. Cell Host Microbe, 29, 2021
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6XEY
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![BU of 6xey by Molmil](/molmil-images/mine/6xey) | Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-4 | Descriptor: | 2-4 Heavy Chain, 2-4 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Rapp, M, Shapiro, L, Ho, D.D. | Deposit date: | 2020-06-14 | Release date: | 2020-07-22 | Last modified: | 2021-01-27 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike. Nature, 584, 2020
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8HK1
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![BU of 8hk1 by Molmil](/molmil-images/mine/8hk1) | The cryo-EM structure of human pre-17S U2 snRNP | Descriptor: | ATP-dependent RNA helicase DDX42, HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, ... | Authors: | Zhang, X, Zhan, X, Shi, Y. | Deposit date: | 2022-11-24 | Release date: | 2023-03-08 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly. Nat Commun, 14, 2023
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8SMV
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![BU of 8smv by Molmil](/molmil-images/mine/8smv) | GPR161 Gs heterotrimer | Descriptor: | CHOLESTEROL, G-protein coupled receptor 161, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Hoppe, N, Manglik, A, Harrison, S. | Deposit date: | 2023-04-26 | Release date: | 2024-02-21 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.74 Å) | Cite: | GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway. Biorxiv, 2023
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6R8X
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6R9W
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![BU of 6r9w by Molmil](/molmil-images/mine/6r9w) | Crystal structure of InhA in complex with AP-124 inhibitor | Descriptor: | (2~{S})-1-(benzimidazol-1-yl)-3-(2,3-dihydro-1~{H}-inden-5-yloxy)propan-2-ol, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Takebayashi, Y, Hinchliffe, P, Spencer, J. | Deposit date: | 2019-04-04 | Release date: | 2019-12-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Discovery of New and Potent InhA Inhibitors as Antituberculosis Agents: Structure-Based Virtual Screening Validated by Biological Assays and X-ray Crystallography. J.Chem.Inf.Model., 60, 2020
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8HBM
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![BU of 8hbm by Molmil](/molmil-images/mine/8hbm) | |
5E6P
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![BU of 5e6p by Molmil](/molmil-images/mine/5e6p) | |
6LBM
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![BU of 6lbm by Molmil](/molmil-images/mine/6lbm) | |
6LBI
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![BU of 6lbi by Molmil](/molmil-images/mine/6lbi) | |
8H7G
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![BU of 8h7g by Molmil](/molmil-images/mine/8h7g) | Cryo-EM structure of the human SAGA complex | Descriptor: | Ataxin-7, STAGA complex 65 subunit gamma, Splicing factor 3B subunit 3, ... | Authors: | Huang, J, Zhang, Y. | Deposit date: | 2022-10-20 | Release date: | 2022-12-14 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Cryo-EM structure of human SAGA transcriptional coactivator complex. Cell Discov, 8, 2022
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8XC4
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![BU of 8xc4 by Molmil](/molmil-images/mine/8xc4) | Nipah virus attachment glycoprotein head domain in complex with a broadly neutralizing antibody 1E5 | Descriptor: | 1E5-VH, 1E5-VL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Fan, P.F, Yu, C.M, Chen, W. | Deposit date: | 2023-12-08 | Release date: | 2024-01-24 | Last modified: | 2024-08-07 | Method: | X-RAY DIFFRACTION (3.24 Å) | Cite: | A potent Henipavirus cross-neutralizing antibody reveals a dynamic fusion-triggering pattern of the G-tetramer. Nat Commun, 15, 2024
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7CQP
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![BU of 7cqp by Molmil](/molmil-images/mine/7cqp) | Complex of TRPC4 and Calmodulin_Nlobe | Descriptor: | CALCIUM ION, Calmodulin-1, Peptide from Short transient receptor potential channel 4 | Authors: | Shen, Z.S. | Deposit date: | 2020-08-11 | Release date: | 2021-06-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Calmodulin binds to Drosophila TRP with an unexpected mode. Structure, 29, 2021
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