7D7R
| Cryo-EM structure of the core domain of human ABCB6 transporter | Descriptor: | ATP-binding cassette sub-family B member 6, mitochondrial | Authors: | Wang, C, Cao, C, Wang, N, Wang, X, Zhang, X.C. | Deposit date: | 2020-10-05 | Release date: | 2020-10-21 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-electron microscopy structure of human ABCB6 transporter. Protein Sci., 29, 2020
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8W9D
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8W9C
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4EKZ
| Crystal structure of reduced hPDI (abb'xa') | Descriptor: | Protein disulfide-isomerase | Authors: | Wang, C, Li, W, Ren, J, Ke, H, Gong, W, Feng, W, Wang, C.-C. | Deposit date: | 2012-04-10 | Release date: | 2013-04-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structural insights into the redox-regulated dynamic conformations of human protein disulfide isomerase Antioxid Redox Signal, 19, 2013
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4EL1
| Crystal structure of oxidized hPDI (abb'xa') | Descriptor: | Protein disulfide-isomerase | Authors: | Wang, C, Li, W, Ren, J, Ke, H, Gong, W, Feng, W, Wang, C.-C. | Deposit date: | 2012-04-10 | Release date: | 2013-04-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.883 Å) | Cite: | Structural insights into the redox-regulated dynamic conformations of human protein disulfide isomerase Antioxid Redox Signal, 19, 2013
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4JQ0
| Voltage-gated sodium channel 1.5 C-terminal domain in complex with FGF12B and Ca2+/calmodulin | Descriptor: | CALCIUM ION, Calmodulin, Fibroblast growth factor 12, ... | Authors: | Wang, C, Chung, B.C, Yan, H, Wang, H.G, Lee, S.Y, Pitt, G.S. | Deposit date: | 2013-03-19 | Release date: | 2014-05-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.84 Å) | Cite: | Structural analyses of Ca(2+)/CaM interaction with NaV channel C-termini reveal mechanisms of calcium-dependent regulation. Nat Commun, 5, 2014
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4JPZ
| Voltage-gated sodium channel 1.2 C-terminal domain in complex with FGF13U and Ca2+/calmodulin | Descriptor: | CALCIUM ION, Calmodulin, Fibroblast growth factor 13, ... | Authors: | Wang, C, Chung, B.C, Yan, H, Wang, H.G, Lee, S.Y, Pitt, G.S. | Deposit date: | 2013-03-19 | Release date: | 2014-04-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.02 Å) | Cite: | Structural analyses of Ca(2+)/CaM interaction with NaV channel C-termini reveal mechanisms of calcium-dependent regulation. Nat Commun, 5, 2014
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5YVN
| Human Glutathione Transferase Omega1 | Descriptor: | ACETATE ION, GLUTATHIONE, Glutathione S-transferase omega-1, ... | Authors: | Saisawang, C, Ketterman, A, Wongsantichon, J. | Deposit date: | 2017-11-27 | Release date: | 2018-11-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Glutathione transferase Omega 1-1 (GSTO1-1) modulates Akt and MEK1/2 signaling in human neuroblastoma cell SH-SY5Y. Proteins, 87, 2019
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5YVO
| Human Glutathione Transferase Omega1 covalently bound to ML175 inhibitor | Descriptor: | ACETATE ION, Glutathione S-transferase omega-1, N-{3-[(2-chloro-acetyl)-(4-nitro-phenyl)-amino]-propyl}-2,2,2-trifluoro-acetamide, ... | Authors: | Saisawang, C, Ketterman, A, Wongsantichon, J. | Deposit date: | 2017-11-27 | Release date: | 2018-11-28 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Glutathione transferase Omega 1-1 (GSTO1-1) modulates Akt and MEK1/2 signaling in human neuroblastoma cell SH-SY5Y. Proteins, 87, 2019
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5E8L
| Crystal structure of geranylgeranyl pyrophosphate synthase 11 from Arabidopsis thaliana | Descriptor: | Heterodimeric geranylgeranyl pyrophosphate synthase large subunit 1, chloroplastic | Authors: | Wang, C, Chen, Q, Fan, D, Li, J, Wang, G, Zhang, P. | Deposit date: | 2015-10-14 | Release date: | 2015-11-11 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.807 Å) | Cite: | Structural Analyses of Short-Chain Prenyltransferases Identify an Evolutionarily Conserved GFPPS Clade in Brassicaceae Plants. Mol Plant, 9, 2016
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5E8H
| Crystal structure of geranylfarnesyl pyrophosphate synthases 2 from Arabidopsis thaliana | Descriptor: | Geranylgeranyl pyrophosphate synthase 3, chloroplastic | Authors: | Wang, C, Chen, Q, Wang, G, Zhang, P. | Deposit date: | 2015-10-14 | Release date: | 2015-11-11 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Analyses of Short-Chain Prenyltransferases Identify an Evolutionarily Conserved GFPPS Clade in Brassicaceae Plants. Mol Plant, 9, 2016
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5E8K
| Crystal structure of polyprenyl pyrophosphate synthase 2 from Arabidopsis thaliana | Descriptor: | Geranylgeranyl pyrophosphate synthase 10, mitochondrial | Authors: | Wang, C, Chen, Q, Fan, D, Li, J, Wang, G, Zhang, P. | Deposit date: | 2015-10-14 | Release date: | 2015-11-11 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.028 Å) | Cite: | Structural Analyses of Short-Chain Prenyltransferases Identify an Evolutionarily Conserved GFPPS Clade in Brassicaceae Plants. Mol Plant, 9, 2016
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8DSP
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8EAP
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8EB7
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8EAN
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8EAO
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8E4G
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6UK1
| Crystal structure of nucleotide-binding domain 2 (NBD2) of the human Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | Authors: | Wang, C, Vorobiev, S.M, Vernon, R.M, Khazanov, N, Senderowitz, H, Forman-Kay, J.D, Hunt, J.F. | Deposit date: | 2019-10-03 | Release date: | 2020-10-07 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.693 Å) | Cite: | A thermodynamically stabilized form of the second nucleotide binding domain from human CFTR shows a catalytically inactive conformation To Be Published
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4M36
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4M38
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4QIM
| Structure of the human smoothened receptor in complex with ANTA XV | Descriptor: | 2-{6-[4-(4-benzylphthalazin-1-yl)piperazin-1-yl]pyridin-3-yl}propan-2-ol, Smoothened homolog/Soluble cytochrome b562 chimeric protein, ZINC ION | Authors: | Wang, C, Wu, H, Evron, T, Vardy, E, Han, G.W, Huang, X.-P, Hufeisen, S.J, Mangano, T.J, Urban, D.J, Katritch, V, Cherezov, V, Caron, M.G, Roth, B.L, Stevens, R.C, GPCR Network (GPCR) | Deposit date: | 2014-05-31 | Release date: | 2014-07-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs. Nat Commun, 5, 2014
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4QIN
| Structure of the human smoothened receptor in complex with SAG1.5 | Descriptor: | 3-chloro-4,7-difluoro-N-[trans-4-(methylamino)cyclohexyl]-N-[3-(pyridin-4-yl)benzyl]-1-benzothiophene-2-carboxamide, Smoothened homolog/Soluble cytochrome b562 chimeric protein | Authors: | Wang, C, Wu, H, Evron, T, Vardy, E, Han, G.W, Huang, X.-P, Hufeisen, S.J, Mangano, T.J, Urban, D.J, Katritch, V, Cherezov, V, Caron, M.G, Roth, B.L, Stevens, R.C, GPCR Network (GPCR) | Deposit date: | 2014-05-31 | Release date: | 2014-07-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs. Nat Commun, 5, 2014
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6KOL
| Crystal structure of auracyanin from photosynthetic bacterium Roseiflexus castenholzii | Descriptor: | Blue (Type 1) copper domain protein, CHLORIDE ION, COPPER (II) ION | Authors: | Wang, C, Zhang, C.Y, Min, Z.Z, Xin, Y.Y, Xu, X.L. | Deposit date: | 2019-08-12 | Release date: | 2020-01-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.211 Å) | Cite: | Structural basis underlying the electron transfer features of a blue copper protein auracyanin from the photosynthetic bacterium Roseiflexus castenholzii. Photosyn. Res., 143, 2020
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4Y33
| Crystal of NO66 in complex with Ni(II)and N-oxalylglycine (NOG) | Descriptor: | Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66, N-OXALYLGLYCINE, NICKEL (II) ION | Authors: | Wang, C, Zhang, Q, Zang, J. | Deposit date: | 2015-02-10 | Release date: | 2015-10-07 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of the JmjC domain-containing protein NO66 complexed with ribosomal protein Rpl8. Acta Crystallogr.,Sect.D, 71, 2015
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