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2C4J
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BU of 2c4j by Molmil
Human glutathione-S-transferase M2-2 T210S mutant in complex with glutathione-styrene oxide conjugate
Descriptor: GLUTATHIONE S-TRANSFERASE MU 2, L-GAMMA-GLUTAMYL-S-[(2S)-2-HYDROXY-2-PHENYLETHYL]-L-CYSTEINYLGLYCINE
Authors:Tars, K, Andersson, M, Ivarsson, Y, Olin, B, Mannervik, B.
Deposit date:2005-10-20
Release date:2005-10-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Alternative Mutations of a Positively Selected Residue Elicit Gain or Loss of Functionalities in Enzyme Evolution.
Proc.Natl.Acad.Sci.USA, 103, 2006
4BF6
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BU of 4bf6 by Molmil
Three dimensional structure of human carbonic anhydrase II in complex with 5-(1-(3-Cyanophenyl)-1H-1,2,3-triazol-4-yl)thiophene-2- sulfonamide
Descriptor: 5-[1-(3-cyanophenyl)-1,2,3-triazol-4-yl]thiophene-2-sulfonamide, CARBONIC ANHYDRASE 2, GLYCEROL, ...
Authors:Tars, K, Leitans, J, Zalubovskis, R.
Deposit date:2013-03-15
Release date:2014-01-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:5-Substituted-(1,2,3-Triazol-4-Yl)Thiophene-2-Sulfonamides Strongly Inhibit Human Carbonic Anhydrases I, II, Ix and Xii: Solution and X-Ray Crystallographic Studies.
Bioorg.Med.Chem., 21, 2013
4BF1
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BU of 4bf1 by Molmil
Three dimensional structure of human carbonic anhydrase II in complex with 5-(1-naphthalen-1-yl-1,2,3-triazol-4-yl)thiophene-2-sulfonamide
Descriptor: 5-(1-naphthalen-1-yl-1,2,3-triazol-4-yl)thiophene-2-sulfonamide, CARBONIC ANHYDRASE 2, SODIUM ION, ...
Authors:Tars, K, Leitans, J, Zalubovskis, R.
Deposit date:2013-03-13
Release date:2014-01-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:5-Substituted-(1,2,3-Triazol-4-Yl)Thiophene-2-Sulfonamides Strongly Inhibit Human Carbonic Anhydrases I, II, Ix and Xii: Solution and X-Ray Crystallographic Studies.
Bioorg.Med.Chem., 21, 2013
2W4Z
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BU of 2w4z by Molmil
Caulobacter bacteriophage 5
Descriptor: ADENOSINE MONOPHOSPHATE, CALCIUM ION, CAULOBACTER BACTERIOPHAGE 5
Authors:Plevka, P, Kazaks, A, Dishlers, A, Liljas, L, Tars, K.
Deposit date:2008-12-02
Release date:2009-07-14
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The Structure of Bacteriophage Phicb5 Reveals a Role of the RNA Genome and Metal Ions in Particle Stability and Assembly.
J.Mol.Biol., 391, 2009
8CQO
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BU of 8cqo by Molmil
Crystal structure of Borrelia burgdorferi paralogous family 12 outer surface protein BBK01 (Se-Met data)
Descriptor: Lipoprotein, putative
Authors:Brangulis, K, Drunka, L, Matisone, S, Akopjana, I, Tars, K.
Deposit date:2023-03-06
Release date:2024-03-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structure of Borrelia burgdorferi outer surface protein BBK01
To Be Published
8CQN
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BU of 8cqn by Molmil
Crystal structure of Borrelia burgdorferi paralogous family 12 outer surface protein BBK01
Descriptor: Lipoprotein, putative
Authors:Brangulis, K, Drunka, L, Matisone, S, Akopjana, I, Tars, K.
Deposit date:2023-03-06
Release date:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of Borrelia burgdorferi outer surface protein BBK01
To Be Published
4Y6M
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BU of 4y6m by Molmil
Structure of plasmepsin II from Plasmodium falciparum complexed with inhibitor PG418
Descriptor: GLYCEROL, Plasmepsin-2, ~{N}1-[(~{Z},3~{R})-4-[2-(3-methoxyphenyl)propan-2-ylamino]-3-oxidanyl-1-phenyl-but-1-en-2-yl]-5-piperidin-1-yl-~{N}3,~{N}3-dipropyl-benzene-1,3-dicarboxamide
Authors:Recacha, R, Akopjana, I, Tars, K, Jaudzems, K.
Deposit date:2015-02-13
Release date:2015-12-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structures of plasmepsin II from Plasmodium falciparum in complex with two hydroxyethylamine-based inhibitors.
Acta Crystallogr.,Sect.F, 71, 2015
5LQP
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BU of 5lqp by Molmil
Cryo-EM reconstruction of bacteriophage AP205 virus-like particles.
Descriptor: Coat protein
Authors:Diebolder, C.A, Rumnieks, J, Tars, K, Koning, R.I.
Deposit date:2016-08-17
Release date:2016-12-14
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structure of AP205 Coat Protein Reveals Circular Permutation in ssRNA Bacteriophages.
J. Mol. Biol., 428, 2016
1FR5
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BU of 1fr5 by Molmil
PHAGE FR CAPSIDS WITH A FOUR RESIDUE DELETION IN THE COAT PROTEIN FG LOOP
Descriptor: BACTERIOPHAGE FR CAPSID
Authors:Axblom, C, Tars, K, Fridborg, K, Bundule, M, Orna, L, Liljas, L.
Deposit date:1998-07-22
Release date:1999-01-13
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of phage fr capsids with a deletion in the FG loop: implications for viral assembly.
Virology, 249, 1998
5JXV
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BU of 5jxv by Molmil
Solid-state MAS NMR structure of immunoglobulin beta 1 binding domain of protein G (GB1)
Descriptor: Immunoglobulin G-binding protein G
Authors:Andreas, L.B, Jaudzems, K, Stanek, J, Lalli, D, Bertarello, A, Le Marchand, T, Cala-De Paepe, D, Kotelovica, S, Akopjana, I, Knott, B, Wegner, S, Engelke, F, Lesage, A, Emsley, L, Tars, K, Herrmann, T, Pintacuda, G.
Deposit date:2016-05-13
Release date:2016-08-10
Last modified:2024-06-19
Method:SOLID-STATE NMR
Cite:Structure of fully protonated proteins by proton-detected magic-angle spinning NMR.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JZR
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BU of 5jzr by Molmil
Solid-state MAS NMR structure of Acinetobacter phage 205 (AP205) coat protein in assembled capsid particles
Descriptor: Coat protein
Authors:Jaudzems, K, Andreas, L.B, Stanek, J, Lalli, D, Bertarello, A, Le Marchand, T, Cala-De Paepe, D, Kotelovica, S, Akopjana, I, Knott, B, Wegner, S, Engelke, F, Lesage, A, Emsley, L, Tars, K, Herrmann, T, Pintacuda, G.
Deposit date:2016-05-17
Release date:2016-08-10
Last modified:2024-06-19
Method:SOLID-STATE NMR
Cite:Structure of fully protonated proteins by proton-detected magic-angle spinning NMR.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JOD
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BU of 5jod by Molmil
Structure of proplasmepsin IV from Plasmodium falciparum
Descriptor: GLYCEROL, Proplasmepsin IV
Authors:Recacha, R, Akopjana, I, Tars, K, Jaudzems, K.
Deposit date:2016-05-02
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.528 Å)
Cite:Crystal structure of Plasmodium falciparum proplasmepsin IV: the plasticity of proplasmepsins.
Acta Crystallogr.,Sect.F, 72, 2016
1X27
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BU of 1x27 by Molmil
Crystal Structure of Lck SH2-SH3 with SH2 binding site of p130Cas
Descriptor: CRK-associated substrate, Proto-oncogene tyrosine-protein kinase LCK, SODIUM ION
Authors:Nasertorabi, F, Tars, K, Becherer, K, Kodandapani, R, Liljas, L, Vuori, K, Ely, K.R.
Deposit date:2005-04-20
Release date:2006-02-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis for regulation of Src by the docking protein p130Cas
J.MOL.RECOG., 19, 2006
4L8H
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BU of 4l8h by Molmil
Bacteriophage Qbeta coat protein in complex with RNA operator hairpin
Descriptor: Coat protein, RNA operator hairpin, ZINC ION
Authors:Rumnieks, J, Tars, K.
Deposit date:2013-06-17
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the bacteriophage q beta coat protein in complex with the RNA operator of the replicase gene.
J.Mol.Biol., 426, 2014
8CO0
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BU of 8co0 by Molmil
Three dimensional structure of human carbonic anhydrase IX in complex with sulfonamide
Descriptor: 5-(5-methyl-6-quinolin-5-yl-pyridin-3-yl)thiophene-2-sulfonamide, Carbonic anhydrase 9, GLYCEROL, ...
Authors:Leitans, J, Tars, K.
Deposit date:2023-02-25
Release date:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Atropo/Tropo Flexibility: A Tool for Design and Synthesis of Self-Adaptable Inhibitors of Carbonic Anhydrases and Their Antiproliferative Effect.
J.Med.Chem., 66, 2023
7PP9
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BU of 7pp9 by Molmil
Three dimensional structure of human carbonic anhydrase XII in complex with sulfonamide
Descriptor: Carbonic anhydrase 12, ZINC ION, methyl 2-chloranyl-4-cyclohexylsulfanyl-5-sulfamoyl-benzoate
Authors:Leitans, J, Tars, K, Dvinskis, E.
Deposit date:2021-09-13
Release date:2022-09-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Methyl 2-Halo-4-Substituted-5-Sulfamoyl-Benzoates as High Affinity and Selective Inhibitors of Carbonic Anhydrase IX.
Int J Mol Sci, 23, 2021
4YA8
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BU of 4ya8 by Molmil
structure of plasmepsin II from Plasmodium Falciparum complexed with inhibitor PG394
Descriptor: GLYCEROL, N'-[(2S,3S)-3-hydroxy-1-phenyl-4-{[2-(pyridin-2-yl)propan-2-yl]amino}butan-2-yl]-N,N-dipropyl-5-(pyridin-1(2H)-yl)benzene-1,3-dicarboxamide, Plasmepsin-2
Authors:Recacha, R, Leitans, J, Tars, K, Jaudzems, K.
Deposit date:2015-02-17
Release date:2015-12-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.301 Å)
Cite:Structures of plasmepsin II from Plasmodium falciparum in complex with two hydroxyethylamine-based inhibitors.
Acta Crystallogr.,Sect.F, 71, 2015
5FS4
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BU of 5fs4 by Molmil
Bacteriophage AP205 coat protein
Descriptor: AP205 BACTERIOPHAGE COAT PROTEIN
Authors:Shishovs, M, Tars, K.
Deposit date:2015-12-29
Release date:2016-09-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structure of Ap205 Coat Protein Reveals Circular Permutation in Ssrna Bacteriophages.
J.Mol.Biol., 428, 2016
5MNT
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BU of 5mnt by Molmil
Bacteriophage Qbeta maturation protein
Descriptor: A2 maturation protein
Authors:Rumnieks, J, Tars, K.
Deposit date:2016-12-13
Release date:2017-01-11
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Crystal Structure of the Maturation Protein from Bacteriophage Q beta.
J. Mol. Biol., 429, 2017
5MJN
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BU of 5mjn by Molmil
Three dimensional structure of human carbonic anhydrase II in complex with 5-[(4Chlorobenzyl)sulfanyl]thiophene-2-sulfonamide
Descriptor: 5-[(4-chlorophenyl)methylsulfanyl]thiophene-2-sulfonamide, Carbonic anhydrase 2, ZINC ION
Authors:Leitans, J, Tars, K.
Deposit date:2016-12-01
Release date:2017-12-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.17 Å)
Cite:5-Substituted-benzylsulfanyl-thiophene-2-sulfonamides with effective carbonic anhydrase inhibitory activity: Solution and crystallographic investigations.
Bioorg. Med. Chem., 25, 2017
8Q4K
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BU of 8q4k by Molmil
Crystal structure of Borrelia burgdorferi BB0158
Descriptor: S2 lipoprotein, SULFATE ION
Authors:Brangulis, K, Tars, K.
Deposit date:2023-08-07
Release date:2024-01-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural studies of chromosomally encoded outer surface lipoprotein BB0158 from Borrelia burgdorferi sensu stricto.
Ticks Tick Borne Dis, 15, 2024
6FL0
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BU of 6fl0 by Molmil
Crystal structure of the membrane attack complex assembly inhibitor BGA71 from Lyme disease agent Borreliella bavariensis
Descriptor: membrane attack complex assembly inhibitor BGA71
Authors:Brangulis, K, Akopjana, I, Petrovskis, I, Kazaks, A, Tars, K.
Deposit date:2018-01-25
Release date:2018-08-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the membrane attack complex assembly inhibitor BGA71 from the Lyme disease agent Borrelia bavariensis.
Sci Rep, 8, 2018
3RLK
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BU of 3rlk by Molmil
Crystal structure of the read-through domain from bacteriophage Qbeta A1 protein, monoclinic crystal form
Descriptor: A1 protein, TETRAETHYLENE GLYCOL
Authors:Rumnieks, J, Tars, K.
Deposit date:2011-04-19
Release date:2011-09-28
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Crystal structure of the read-through domain from bacteriophage Qbeta A1 protein
Protein Sci., 20, 2011
3RLC
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BU of 3rlc by Molmil
Crystal structure of the read-through domain from bacteriophage Qbeta A1 protein, hexagonal crystal form
Descriptor: A1 protein, TETRAETHYLENE GLYCOL
Authors:Rumnieks, J, Tars, K.
Deposit date:2011-04-19
Release date:2011-09-28
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the read-through domain from bacteriophage Qbeta A1 protein
Protein Sci., 20, 2011
8QO1
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BU of 8qo1 by Molmil
Asymmetric structure of the Borrelia bacteriophage BB1 procapsid, 3D class 3
Descriptor: Cytosolic protein, DUF228 domain-containing protein, Decoration protein P03, ...
Authors:Rumnieks, J, Fuzik, T, Tars, K.
Deposit date:2023-10-11
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (9.76 Å)
Cite:Structure of the Borrelia Bacteriophage phi BB1 Procapsid.
J.Mol.Biol., 435, 2023

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