4BF6

Three dimensional structure of human carbonic anhydrase II in complex with 5-(1-(3-Cyanophenyl)-1H-1,2,3-triazol-4-yl)thiophene-2- sulfonamide

Summary for 4BF6

• Entry DOI: 10.2210/pdb4bf6/pdb
• Related: 4BF1
• Descriptor: CARBONIC ANHYDRASE 2, ZINC ION, 5-[1-(3-cyanophenyl)-1,2,3-triazol-4-yl]thiophene-2-sulfonamide, ... (5 entities in total)
• Functional Keywords: lyase
• Biological source: HOMO SAPIENS
• Total number of polymer chains: 1
• Total formula weight: 29646.74

Authors

Tars, K.,Leitans, J.,Zalubovskis, R. (deposition date: 2013-03-15, release date: 2014-01-22, Last modification date: 2023-12-20)

• Primary citation: Leitans, J.,Sprudza, A.,Tanc, M.,Vozny, I.,Zalubovskis, R.,Tars, K.,Supuran, C.T.; 5-Substituted-(1,2,3-Triazol-4-Yl)Thiophene-2-Sulfonamides Strongly Inhibit Human Carbonic Anhydrases I, II, Ix and Xii: Solution and X-Ray Crystallographic Studies.; Bioorg.Med.Chem., 21:5130-, 2013; PubMed: 23859774; DOI: 10.1016/J.BMC.2013.06.041

Experimental method

X-RAY DIFFRACTION (1.82 Å)