4BF1
Three dimensional structure of human carbonic anhydrase II in complex with 5-(1-naphthalen-1-yl-1,2,3-triazol-4-yl)thiophene-2-sulfonamide
Summary for 4BF1
Entry DOI | 10.2210/pdb4bf1/pdb |
Related | 4BF6 |
Descriptor | CARBONIC ANHYDRASE 2, ZINC ION, 5-(1-naphthalen-1-yl-1,2,3-triazol-4-yl)thiophene-2-sulfonamide, ... (5 entities in total) |
Functional Keywords | lyase |
Biological source | HOMO SAPIENS |
Total number of polymer chains | 1 |
Total formula weight | 29602.68 |
Authors | Tars, K.,Leitans, J.,Zalubovskis, R. (deposition date: 2013-03-13, release date: 2014-01-22, Last modification date: 2023-12-20) |
Primary citation | Leitans, J.,Sprudza, A.,Tanc, M.,Vozny, I.,Zalubovskis, R.,Tars, K.,Supuran, C.T. 5-Substituted-(1,2,3-Triazol-4-Yl)Thiophene-2-Sulfonamides Strongly Inhibit Human Carbonic Anhydrases I, II, Ix and Xii: Solution and X-Ray Crystallographic Studies. Bioorg.Med.Chem., 21:5130-, 2013 Cited by PubMed: 23859774DOI: 10.1016/J.BMC.2013.06.041 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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