3FUO
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![BU of 3fuo by Molmil](/molmil-images/mine/3fuo) | The Crystal structure of receptor binding domain of botulinum neurotoxin serotype A | Descriptor: | Botulinum neurotoxin type A | Authors: | Fu, Z, Chen, C, Barbieri, J.T, Kim, J.-J.P, Baldwin, M.R. | Deposit date: | 2009-01-14 | Release date: | 2009-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F Biochemistry, 48, 2009
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3HN1
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![BU of 3hn1 by Molmil](/molmil-images/mine/3hn1) | Crystal structure of HCR/T complexed with GT2 and lactose | Descriptor: | N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid, SULFATE ION, Tetanus toxin, ... | Authors: | Chen, C, Fu, Z, Kim, J.-J.P, Barbieri, J.T, Baldwin, M.R. | Deposit date: | 2009-05-29 | Release date: | 2009-07-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Gangliosides as high affinity receptors for tetanus neurotoxin. J.Biol.Chem., 284, 2009
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3HMY
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![BU of 3hmy by Molmil](/molmil-images/mine/3hmy) | Crystal structure of HCR/T complexed with GT2 | Descriptor: | GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid, SULFATE ION, ... | Authors: | Chen, C, Fu, Z, Kim, J.-J.P, Barbieri, J.T, Baldwin, M.R. | Deposit date: | 2009-05-29 | Release date: | 2009-07-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Gangliosides as high affinity receptors for tetanus neurotoxin. J.Biol.Chem., 284, 2009
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2G7P
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![BU of 2g7p by Molmil](/molmil-images/mine/2g7p) | Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to Small Molecule Inhibitors | Descriptor: | Botulinum neurotoxin type A, ZINC ION | Authors: | Fu, Z, Baldwin, M.R, Boldt, G.E, Janda, K.D, Barbieri, J.T, Kim, J.-J.P. | Deposit date: | 2006-02-28 | Release date: | 2006-08-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate. Biochemistry, 45, 2006
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3MP4
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![BU of 3mp4 by Molmil](/molmil-images/mine/3mp4) | Crystal structure of Human lyase R41M mutant | Descriptor: | Hydroxymethylglutaryl-CoA lyase | Authors: | Fu, Z, Runquist, J.A, Montgomery, C, Miziorko, H.M, Kim, J.-J.P. | Deposit date: | 2010-04-24 | Release date: | 2010-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Functional insights into human HMG-CoA lyase from structures of Acyl-CoA-containing ternary complexes. J.Biol.Chem., 285, 2010
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3MP3
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![BU of 3mp3 by Molmil](/molmil-images/mine/3mp3) | Crystal Structure of Human Lyase in complex with inhibitor HG-CoA | Descriptor: | (3R,5S,9R,21S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9,21-tetrahydroxy-8,8-dimethyl-10,14,19-trioxo-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatricosan-23-oic acid 3,5-dioxide, 3-HYDROXYPENTANEDIOIC ACID, Hydroxymethylglutaryl-CoA lyase, ... | Authors: | Fu, Z, Runquist, J.A, Montgomery, C, Miziorko, H.M, Kim, J.-J.P. | Deposit date: | 2010-04-24 | Release date: | 2010-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Functional insights into human HMG-CoA lyase from structures of Acyl-CoA-containing ternary complexes. J.Biol.Chem., 285, 2010
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3MP5
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![BU of 3mp5 by Molmil](/molmil-images/mine/3mp5) | Crystal Structure of Human Lyase R41M in complex with HMG-CoA | Descriptor: | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, Hydroxymethylglutaryl-CoA lyase, MAGNESIUM ION | Authors: | Fu, Z, Runquist, J.A, Montgomery, C, Miziorko, H.M, Kim, J.-J.P. | Deposit date: | 2010-04-24 | Release date: | 2010-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Functional insights into human HMG-CoA lyase from structures of Acyl-CoA-containing ternary complexes. J.Biol.Chem., 285, 2010
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2G7Q
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![BU of 2g7q by Molmil](/molmil-images/mine/2g7q) | Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to Small Molecule Inhibitors | Descriptor: | Botulinum neurotoxin type A, N-HYDROXY-L-ARGININAMIDE, ZINC ION | Authors: | Fu, Z, Baldwin, M.R, Boldt, G.E, Janda, K.D, Barbieri, J.T, Kim, J.-J.P. | Deposit date: | 2006-02-28 | Release date: | 2006-08-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate. Biochemistry, 45, 2006
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2GMH
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![BU of 2gmh by Molmil](/molmil-images/mine/2gmh) | Structure of Porcine Electron Transfer Flavoprotein-Ubiquinone Oxidoreductase in Complexed with Ubiquinone | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIMETHOXY-5-METHYL-6-(3,11,15,19-TETRAMETHYL-EICOSA-2,6,10,14,18-PENTAENYL)-[1,4]BENZOQUINONE, Electron transfer flavoprotein-ubiquinone oxidoreductase, ... | Authors: | Zhang, J, Frerman, F.E, Kim, J.-J.P. | Deposit date: | 2006-04-06 | Release date: | 2006-10-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of electron transfer flavoprotein-ubiquinone oxidoreductase and electron transfer to the mitochondrial ubiquinone pool. Proc.Natl.Acad.Sci.Usa, 103, 2006
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3N7K
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![BU of 3n7k by Molmil](/molmil-images/mine/3n7k) | Crystal structure of botulinum neurotoxin serotype C1 binding domain | Descriptor: | Botulinum neurotoxin type C1 | Authors: | Fu, Z, Kroken, A, Karalewitz, A, Baldwin, M.R, Barbieri, J.T, Kim, J.-J.P. | Deposit date: | 2010-05-27 | Release date: | 2010-09-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA . Biochemistry, 49, 2010
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3N7J
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![BU of 3n7j by Molmil](/molmil-images/mine/3n7j) | Crystal structure of botulinum neurotoxin serotype D binding domain | Descriptor: | Botulinum neurotoxin type D | Authors: | Fu, Z, Baldwin, M.R, Karalewitz, A, Kroken, A, Barbieri, J.T, Kim, J.-J.P. | Deposit date: | 2010-05-27 | Release date: | 2010-09-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA . Biochemistry, 49, 2010
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3N7M
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![BU of 3n7m by Molmil](/molmil-images/mine/3n7m) | Crystal structure of W1252A mutant of HCR D/C VPI 5995 | Descriptor: | GLYCEROL, Neurotoxin, SULFATE ION | Authors: | Fu, Z, Karalewitz, A, Kroken, A, Baldwin, M.R, Barbieri, J.T, Kim, J.-J.P. | Deposit date: | 2010-05-27 | Release date: | 2010-09-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA . Biochemistry, 49, 2010
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3N7L
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![BU of 3n7l by Molmil](/molmil-images/mine/3n7l) | Crystal structure of botulinum neurotoxin serotype D/C VPI 5993 binding domain | Descriptor: | GLYCEROL, Neurotoxin, SULFATE ION | Authors: | Fu, Z, Karalewitz, A, Kroken, A, Baldwin, M.R, Barbieri, J.T, Kim, J.-J.P. | Deposit date: | 2010-05-27 | Release date: | 2010-09-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA . Biochemistry, 49, 2010
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2G7K
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![BU of 2g7k by Molmil](/molmil-images/mine/2g7k) | Structure of the Light Chain of Botulinum Neurotoxin, Serotype A Bound to small Molecule Inhibitors | Descriptor: | Botulinum neurotoxin type A | Authors: | Fu, Z, Baldwin, M.R, Boldt, G.E, Crawford, A, Janda, K.D, Barbieri, J.T, Kim, J.-J.P. | Deposit date: | 2006-02-28 | Release date: | 2006-08-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate. Biochemistry, 45, 2006
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2GMJ
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![BU of 2gmj by Molmil](/molmil-images/mine/2gmj) | Structure of Porcine Electron Transfer Flavoprotein-Ubiquinone Oxidoreductase | Descriptor: | Electron transfer flavoprotein-ubiquinone oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE, IRON/SULFUR CLUSTER, ... | Authors: | Zhang, J, Frerman, F.E, Kim, J.-J.P. | Deposit date: | 2006-04-06 | Release date: | 2006-10-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of electron transfer flavoprotein-ubiquinone oxidoreductase and electron transfer to the mitochondrial ubiquinone pool. Proc.Natl.Acad.Sci.Usa, 103, 2006
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3OJW
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![BU of 3ojw by Molmil](/molmil-images/mine/3ojw) | Disulfide crosslinked cytochrome P450 reductase inactive | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADPH-cytochrome P450 reductase | Authors: | Xia, C, Hamdane, D, Shen, A, Choi, V, Kasper, C, Zhang, H, Im, S.-C, Waskell, L, Kim, J.-J.P. | Deposit date: | 2010-08-23 | Release date: | 2011-02-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Conformational Changes of NADPH-Cytochrome P450 Oxidoreductase Are Essential for Catalysis and Cofactor Binding. J.Biol.Chem., 286, 2011
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3QE2
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![BU of 3qe2 by Molmil](/molmil-images/mine/3qe2) | Crystal Structure of Human NADPH-Cytochrome P450 Reductase | Descriptor: | CALCIUM ION, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Xia, C, Marohnic, C, Panda, S.P, Masters, B.S, Kim, J.-J.P. | Deposit date: | 2011-01-19 | Release date: | 2011-08-03 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency. Proc.Natl.Acad.Sci.USA, 108, 2011
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3QFT
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![BU of 3qft by Molmil](/molmil-images/mine/3qft) | Crystal Structure of NADPH-Cytochrome P450 Reductase (FAD/NADPH domain and R457H Mutant) | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH--cytochrome P450 reductase | Authors: | Xia, C, Marohnic, C, Panda, S.P, Masters, B.S, Kim, J.-J.P. | Deposit date: | 2011-01-22 | Release date: | 2011-08-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency. Proc.Natl.Acad.Sci.USA, 108, 2011
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3QFR
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![BU of 3qfr by Molmil](/molmil-images/mine/3qfr) | Crystal Structure of Human NADPH-Cytochrome P450 Reductase (R457H Mutant) | Descriptor: | CALCIUM ION, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Xia, C, Marohnic, C, Panda, S.P, Masters, B.S, Kim, J.-J.P. | Deposit date: | 2011-01-22 | Release date: | 2011-08-03 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency. Proc.Natl.Acad.Sci.USA, 108, 2011
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3QFS
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![BU of 3qfs by Molmil](/molmil-images/mine/3qfs) | Crystal Structure of NADPH-Cytochrome P450 Reductase (FAD/NADPH domain) | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH--cytochrome P450 reductase | Authors: | Xia, C, Marohnic, C, Panda, S.P, Masters, B.S, Kim, J.-J.P. | Deposit date: | 2011-01-22 | Release date: | 2011-08-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency. Proc.Natl.Acad.Sci.USA, 108, 2011
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3QFC
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![BU of 3qfc by Molmil](/molmil-images/mine/3qfc) | Crystal Structure of Human NADPH-Cytochrome P450 (V492E mutant) | Descriptor: | CALCIUM ION, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Xia, C, Marohnic, C, Panda, S.P, Masters, B.S, Kim, J.-J.P. | Deposit date: | 2011-01-21 | Release date: | 2011-08-03 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency. Proc.Natl.Acad.Sci.USA, 108, 2011
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3RMX
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![BU of 3rmx by Molmil](/molmil-images/mine/3rmx) | Crystal structure of HCR/D F1240A mutant | Descriptor: | Botulinum neurotoxin type D | Authors: | Fu, Z, Karalewitz, A, Kroken, A, Kim, J.-J.P, Barbieri, J.T. | Deposit date: | 2011-04-21 | Release date: | 2011-06-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Novel Ganglioside-mediated Entry of Botulinum Neurotoxin Serotype D into Neurons. J.Biol.Chem., 286, 2011
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3OJX
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![BU of 3ojx by Molmil](/molmil-images/mine/3ojx) | Disulfide crosslinked cytochrome P450 reductase inactive | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Xia, C, Hamdane, D, Shen, A, Choi, V, Kasper, C, Zhang, H, Im, S.-C, Waskell, L, Kim, J.-J.P. | Deposit date: | 2010-08-23 | Release date: | 2011-02-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Conformational Changes of NADPH-Cytochrome P450 Oxidoreductase Are Essential for Catalysis and Cofactor Binding. J.Biol.Chem., 286, 2011
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3RMY
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![BU of 3rmy by Molmil](/molmil-images/mine/3rmy) | Crystal structure of HCR/D W1238A mutant | Descriptor: | Botulinum neurotoxin type D, GLYCEROL | Authors: | Fu, Z, Karalewitz, A, Kroken, A, Kim, J.-J.P, Barbieri, J.T. | Deposit date: | 2011-04-21 | Release date: | 2011-06-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Novel Ganglioside-mediated Entry of Botulinum Neurotoxin Serotype D into Neurons. J.Biol.Chem., 286, 2011
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3RSJ
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![BU of 3rsj by Molmil](/molmil-images/mine/3rsj) | Structure of HCRF in complex with Ganglioside GD1a | Descriptor: | BoNT/F, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose, ... | Authors: | Fu, Z, Benson, M.A, Barbieri, J.T, Kim, J.-J.P, Baldwin, M.R. | Deposit date: | 2011-05-02 | Release date: | 2011-08-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Unique ganglioside recognition strategies for clostridial neurotoxins. J.Biol.Chem., 286, 2011
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