4M01
| N terminal fragment(residues 245-575) of binding region of SraP | Descriptor: | CALCIUM ION, GLYCEROL, Serine-rich adhesin for platelets | Authors: | Yang, Y.H, Jiang, Y.L, Zhang, J, Wang, L, Chen, Y, Zhou, C.Z. | Deposit date: | 2013-08-01 | Release date: | 2014-06-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Insights into SraP-Mediated Staphylococcus aureus Adhesion to Host Cells Plos Pathog., 10, 2014
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4JI0
| Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | Descriptor: | 16S rRNA, MAGNESIUM ION, ZINC ION, ... | Authors: | Demirci, H, Wang, L, Murphy IV, F, Murphy, E, Carr, J, Blanchard, S, Jogl, G, Dahlberg, A.E, Gregory, S.T. | Deposit date: | 2013-03-05 | Release date: | 2013-11-06 | Last modified: | 2013-12-04 | Method: | X-RAY DIFFRACTION (3.492 Å) | Cite: | The central role of protein S12 in organizing the structure of the decoding site of the ribosome. Rna, 19, 2013
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4JI7
| Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | Descriptor: | 16S rRNA, MAGNESIUM ION, RIBOSOMAL PROTEIN S10, ... | Authors: | Demirci, H, Wang, L, Murphy IV, F, Murphy, E, Carr, J, Blanchard, S, Jogl, G, Dahlberg, A.E, Gregory, S.T. | Deposit date: | 2013-03-05 | Release date: | 2013-11-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | The central role of protein S12 in organizing the structure of the decoding site of the ribosome. Rna, 19, 2013
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4M00
| Crystal structure of the ligand binding region of staphylococcal adhesion SraP | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Serine-rich adhesin for platelets, ... | Authors: | Yang, Y.H, Jiang, Y.L, Zhang, J, Wang, L, Chen, Y, Zhou, C.Z. | Deposit date: | 2013-08-01 | Release date: | 2014-06-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural Insights into SraP-Mediated Staphylococcus aureus Adhesion to Host Cells Plos Pathog., 10, 2014
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5XM5
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3QTC
| Crystal structure of the catalytic domain of MmOmeRS, an O-methyl tyrosyl-tRNA synthetase evolved from Methanosarcina mazei PylRS, complexed with O-methyl tyrosine and AMP-PNP | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, O-methyl-L-tyrosine, ... | Authors: | Dellas, N, Takimoto, J.K, Noel, J.P, Wang, L. | Deposit date: | 2011-02-22 | Release date: | 2011-05-25 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Stereochemical Basis for Engineered Pyrrolysyl-tRNA Synthetase and the Efficient in Vivo Incorporation of Structurally Divergent Non-native Amino Acids. Acs Chem.Biol., 6, 2011
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5YXC
| Crystal structure of Zinc binding protein ZinT in complex with citrate from E. coli | Descriptor: | CITRIC ACID, Metal-binding protein ZinT, ZINC ION | Authors: | Chen, J, Wang, L, Shang, F, Xu, Y. | Deposit date: | 2017-12-04 | Release date: | 2017-12-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.763 Å) | Cite: | Crystal structure of E. coli ZinT with one zinc-binding mode and complexed with citrate Biochem. Biophys. Res. Commun., 500, 2018
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4OJR
| Crystal Structure of the HIV-1 Integrase catalytic domain with GSK1264 | Descriptor: | (2S)-tert-butoxy[4-(8-fluoro-5-methyl-3,4-dihydro-2H-chromen-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinolin-3-yl]ethanoic acid, CACODYLATE ION, HIV-1 Integrase, ... | Authors: | Gupta, K, Brady, T, Dyer, B, Hwang, Y, Male, F, Nolte, R.T, Wang, L, Velthuisen, E, Jeffrey, J, Van Duyne, G, Bushman, F.D. | Deposit date: | 2014-01-21 | Release date: | 2014-06-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Allosteric Inhibition of Human Immunodeficiency Virus Integrase: LATE BLOCK DURING VIRAL REPLICATION AND ABNORMAL MULTIMERIZATION INVOLVING SPECIFIC PROTEIN DOMAINS. J.Biol.Chem., 289, 2014
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5Z7H
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5Z72
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4PIV
| Human Fatty Acid Synthase Psi/KR Tri-Domain with NADPH and GSK2194069 | Descriptor: | 4-[4-(1-benzofuran-5-yl)phenyl]-5-{[(3S)-1-(cyclopropylcarbonyl)pyrrolidin-3-yl]methyl}-2,4-dihydro-3H-1,2,4-triazol-3-one, CACODYLATE ION, Fatty acid synthase, ... | Authors: | Williams, S.P, Wang, L, Brown, K.K, Parrish, C.A, Hardwicke, M.A. | Deposit date: | 2014-05-09 | Release date: | 2014-07-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.299 Å) | Cite: | A human fatty acid synthase inhibitor binds beta-ketoacyl reductase in the keto-substrate site. Nat.Chem.Biol., 10, 2014
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7Y42
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7DRI
| Structure of SspE_CTD_41658 | Descriptor: | DUF1524 domain | Authors: | Haiyan, G, Jinchuan, Z, Chen, S, Wang, L, Wu, G. | Deposit date: | 2020-12-28 | Release date: | 2022-06-29 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE. Nat Commun, 13, 2022
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3U1M
| Structure of the mRNA splicing complex component Cwc2 | Descriptor: | Pre-mRNA-splicing factor CWC2, ZINC ION | Authors: | Lu, P, Lu, G, Yan, C, Wang, L, Li, W, Yin, P. | Deposit date: | 2011-09-30 | Release date: | 2011-11-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of the mRNA splicing complex component Cwc2: insights into RNA recognition Biochem.J., 441, 2012
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3U4R
| Novel HCV NS5B polymerase Inhibitors: Discovery of Indole C2 Acyl sulfonamides | Descriptor: | 1-[(2-aminopyridin-4-yl)methyl]-5-chloro-N-({3-[(methylsulfonyl)amino]phenyl}sulfonyl)-3-(2-oxo-1,2-dihydropyridin-3-yl)-1H-indole-2-carboxamide, RNA-directed RNA polymerase | Authors: | Anilkumar, G.N, Selyutin, O, Rosenblum, S.B, Zeng, Q, Jiang, Y, Chan, T.-Y, Pu, H, Wang, L, Bennett, F, Chen, K.X, Lesburg, C.A, Duca, J.S, Gavalas, S, Huang, Y, Pinto, P, Sannagrahi, M, Velazquez, F, Venkataraman, S, Vilbubhan, B, Agrawal, S, Ferrari, E, Jiang, C.-K, Huang, H.-C, Shih, N.-Y, Njoroge, F.G, Kozlowski, J.A. | Deposit date: | 2011-10-10 | Release date: | 2011-12-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | II. Novel HCV NS5B polymerase inhibitors: Discovery of indole C2 acyl sulfonamides. Bioorg.Med.Chem.Lett., 22, 2012
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3U1L
| Structure of the mRNA splicing complex component Cwc2 | Descriptor: | Pre-mRNA-splicing factor CWC2, ZINC ION | Authors: | Lu, P, Lu, G, Yan, C, Wang, L, Li, W, Yin, P. | Deposit date: | 2011-09-30 | Release date: | 2011-11-16 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structure of the mRNA splicing complex component Cwc2: insights into RNA recognition Biochem.J., 441, 2012
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2MY9
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7L7G
| Electron cryo-microscopy of the eukaryotic translation initiation factor 2B from Homo sapiens (updated model of PDB ID: 6CAJ) | Descriptor: | 2-(4-chloranylphenoxy)-~{N}-[4-[2-(4-chloranylphenoxy)ethanoylamino]cyclohexyl]ethanamide, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, ... | Authors: | Tsai, J.C, Miller-Vedam, L.E, Anand, A, Jaishankar, P, Nguyen, H.C, Wang, L, Renslo, A.R, Frost, A, Walter, P. | Deposit date: | 2020-12-28 | Release date: | 2021-03-24 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | eIF2B conformation and assembly state regulates the integrated stress response. Elife, 10, 2021
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7DRS
| Structure of SspE_40224 | Descriptor: | SspE protein | Authors: | Haiyan, G, Jinchuan, Z, Chen, S, Wang, L, Wu, G. | Deposit date: | 2020-12-29 | Release date: | 2022-06-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.42 Å) | Cite: | Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE. Nat Commun, 13, 2022
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7DRR
| Structure of SspE-R100A protein | Descriptor: | SspE protein | Authors: | Haiyan, G, Jinchuan, Z, Chen, S, Wang, L, Wu, G. | Deposit date: | 2020-12-29 | Release date: | 2022-06-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.48 Å) | Cite: | Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE. Nat Commun, 13, 2022
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7E5R
| SARS-CoV-2 S trimer with three-antibody cocktail complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FC05 heavy chain, FC05 light chain, ... | Authors: | Sun, Y, Wang, L, Wang, N, Feng, R, Wang, X. | Deposit date: | 2021-02-20 | Release date: | 2021-10-13 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure-based development of three- and four-antibody cocktails against SARS-CoV-2 via multiple mechanisms. Cell Res., 31, 2021
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7E5S
| SARS-CoV-2 S trimer with four-antibody cocktail complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FC05 heavy chain, FC05 light chain, ... | Authors: | Sun, Y, Wang, L, Wang, N, Feng, R, Wang, X. | Deposit date: | 2021-02-20 | Release date: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure-based development of three- and four-antibody cocktails against SARS-CoV-2 via multiple mechanisms. Cell Res., 31, 2021
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2HPJ
| Crystal structure of the PUB domain of mouse PNGase | Descriptor: | GLYCEROL, PNGase | Authors: | Zhao, G, Zhou, X, Wang, L, Li, G, Lennarz, W, Schindelin, H. | Deposit date: | 2006-07-17 | Release date: | 2007-05-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Studies on peptide:N-glycanase-p97 interaction suggest that p97 phosphorylation modulates endoplasmic reticulum-associated degradation. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2JAS
| Structure of deoxyadenosine kinase from M.mycoides with bound dATP | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DEOXYGUANOSINE KINASE, MAGNESIUM ION | Authors: | Welin, M, Wang, L, Eriksson, S, Eklund, H. | Deposit date: | 2006-11-30 | Release date: | 2007-01-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure-Function Analysis of a Bacterial Deoxyadenosine Kinase Reveals the Basis for Substrate Specificity. J.Mol.Biol., 366, 2007
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2JA1
| Thymidine kinase from B. cereus with TTP bound as phosphate donor. | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, THYMIDINE KINASE, THYMIDINE-5'-TRIPHOSPHATE, ... | Authors: | Kosinska, U, Carnrot, C, Sandrini, M.P.B, Clausen, A.R, Wang, L, Piskur, J, Eriksson, S, Eklund, H. | Deposit date: | 2006-11-17 | Release date: | 2007-01-23 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Studies of Thymidine Kinases from Bacillus Anthracis and Bacillus Cereus Provide Insights Into Quaternary Structure and Conformational Changes Upon Substrate Binding FEBS J., 274, 2007
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