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PDB: 1 results

4PIV
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Human Fatty Acid Synthase Psi/KR Tri-Domain with NADPH and GSK2194069
Descriptor: 4-[4-(1-benzofuran-5-yl)phenyl]-5-{[(3S)-1-(cyclopropylcarbonyl)pyrrolidin-3-yl]methyl}-2,4-dihydro-3H-1,2,4-triazol-3-one, CACODYLATE ION, Fatty acid synthase, ...
Authors:Williams, S.P, Wang, L, Brown, K.K, Parrish, C.A, Hardwicke, M.A.
Deposit date:2014-05-09
Release date:2014-07-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:A human fatty acid synthase inhibitor binds beta-ketoacyl reductase in the keto-substrate site.
Nat.Chem.Biol., 10, 2014

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