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6KMV
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BU of 6kmv by Molmil
caspase-11 C254A P22/P10 in complex with mouse GSDMD-C domain
Descriptor: Caspase-4, Gasdermin-D
Authors:Ding, J, Sun, Q.
Deposit date:2019-08-01
Release date:2020-03-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020
3MAW
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BU of 3maw by Molmil
Structure of the Newcastle disease virus F protein in the post-fusion conformation
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
Authors:Jardetzky, T.S, Wen, X.
Deposit date:2010-03-24
Release date:2010-05-26
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of the Newcastle disease virus F protein in the post-fusion conformation.
Virology, 402, 2010
6KN1
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BU of 6kn1 by Molmil
P20/P12 of caspase-11 mutant C254A
Descriptor: Caspase-4
Authors:Ding, J, Sun, Q.
Deposit date:2019-08-02
Release date:2020-03-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020
3DNJ
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BU of 3dnj by Molmil
The structure of the Caulobacter crescentus ClpS protease adaptor protein in complex with a N-end rule peptide
Descriptor: ATP-dependent Clp protease adapter protein clpS, MAGNESIUM ION, synthetic N-end rule peptide
Authors:Wang, K, Roman-Hernandez, G, Grant, R.A, Sauer, R.T, Baker, T.A.
Deposit date:2008-07-02
Release date:2008-11-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:The molecular basis of N-end rule recognition.
Mol.Cell, 32, 2008
7XY4
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BU of 7xy4 by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with VHH21
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, VHH21
Authors:Cao, D, Fan, X, Zhang, X.
Deposit date:2022-05-31
Release date:2023-09-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Identification of nano-abzymes to catalyze the spike-trimer of SARS-CoV-2
To Be Published
7XY3
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BU of 7xy3 by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with VHH14
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, VHH14
Authors:Cao, D, Fan, X, Zhang, X.
Deposit date:2022-05-31
Release date:2023-09-13
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Identification of nano-abzymes to catalyze the spike-trimer of SARS-CoV-2
To Be Published
3SGY
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BU of 3sgy by Molmil
Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ETHYL-5-[(3S)-3-[3-METHOXY-5-(PYRIDIN-4-YL)PHENYL]BUT-1-YN-1-YL]PYRIMIDINE-2,4-DIAMINE (UCP1006)
Descriptor: 6-ethyl-5-{(3S)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Frey, K.M, Anderson, A.C.
Deposit date:2011-06-15
Release date:2012-03-07
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.598 Å)
Cite:Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes.
Plos One, 7, 2012
3SH2
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BU of 3sh2 by Molmil
Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ethyl-5-(3-(4-methoxybiphenyl-3-yl)prop-1-ynyl)pyrimidine-2,4-diamine (UCP120J)
Descriptor: 6-ethyl-5-[3-(4-methoxybiphenyl-3-yl)prop-1-yn-1-yl]pyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Frey, K.M, Anderson, A.C.
Deposit date:2011-06-15
Release date:2012-03-07
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.999 Å)
Cite:Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes.
Plos One, 7, 2012
7F70
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BU of 7f70 by Molmil
Crystal structure of Rv3094c
Descriptor: Rv3094c
Authors:Wang, Z.X, Ouyang, S.Y, Zhang, H.T.
Deposit date:2021-06-26
Release date:2022-06-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Omics analysis of Mycobacterium tuberculosis isolates uncovers Rv3094c, an ethionamide metabolism-associated gene.
Commun Biol, 6, 2023
7F74
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BU of 7f74 by Molmil
Rv3094c in complex with FMN.
Descriptor: FLAVIN MONONUCLEOTIDE, Rv3094c
Authors:Wang, Z.X, Ouyang, S.Y.
Deposit date:2021-06-27
Release date:2022-06-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Omics analysis of Mycobacterium tuberculosis isolates uncovers Rv3094c, an ethionamide metabolism-associated gene.
Commun Biol, 6, 2023
7F72
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BU of 7f72 by Molmil
Rv3094c in complex with FAD and ETH.
Descriptor: 2-ethylpyridine-4-carboximidothioic acid, FLAVIN MONONUCLEOTIDE, Rv3094c
Authors:Wang, Z.X, Ouyang, S.Y.
Deposit date:2021-06-27
Release date:2022-07-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Omics analysis of Mycobacterium tuberculosis isolates uncovers Rv3094c, an ethionamide metabolism-associated gene.
Commun Biol, 6, 2023
2HKO
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BU of 2hko by Molmil
Crystal structure of LSD1
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1
Authors:Chen, Y, Yang, Y.T, Wang, F, Yanane, K, Zhang, Y, Lei, M.
Deposit date:2006-07-05
Release date:2006-08-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of human histone lysine-specific demethylase 1 (LSD1).
Proc.Natl.Acad.Sci.Usa, 103, 2006
4M7C
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BU of 4m7c by Molmil
Crystal structure of the TRF2-binding motif of SLX4 in complex with the TRFH domain of TRF2
Descriptor: Peptide from Structure-specific endonuclease subunit SLX4, Telomeric repeat-binding factor 2
Authors:Wan, B, Chen, Y, Wu, J, Liu, Y, Lei, M.
Deposit date:2013-08-12
Release date:2013-09-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:SLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with Telomeres
Cell Rep, 4, 2013
4Y7E
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BU of 4y7e by Molmil
Crystal structure of beta-mannanase from Streptomyces thermolilacinus with mannohexaose
Descriptor: CALCIUM ION, Endoglucanase, GLYCEROL, ...
Authors:Kumagai, Y, Yamashita, K, Okuyama, M, Hatanaka, T, Yao, M, Kimura, A.
Deposit date:2015-02-14
Release date:2015-09-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The loop structure of Actinomycete glycoside hydrolase family 5 mannanases governs substrate recognition
Febs J., 282, 2015
3U84
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BU of 3u84 by Molmil
Crystal Structure of Human Menin
Descriptor: Menin
Authors:Huang, J, Wan, B, Lei, M.
Deposit date:2011-10-15
Release date:2012-02-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
Nature, 482, 2012
3U86
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BU of 3u86 by Molmil
Crystal structure of human menin in complex with JunD
Descriptor: Menin, Transcription factor jun-D
Authors:Huang, J, Wan, B, Lei, M.
Deposit date:2011-10-15
Release date:2012-02-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.843 Å)
Cite:The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
Nature, 482, 2012
3U85
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BU of 3u85 by Molmil
Crystal structure of human menin in complex with MLL1
Descriptor: Histone-lysine N-methyltransferase 2A, Menin
Authors:Huang, J, Wan, B, Lei, M.
Deposit date:2011-10-15
Release date:2012-02-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
Nature, 482, 2012
3U88
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BU of 3u88 by Molmil
Crystal structure of human menin in complex with MLL1 and LEDGF
Descriptor: (4beta,8alpha,9R)-6'-methoxy-10,11-dihydrocinchonan-9-ol, CHOLIC ACID, GLYOXYLIC ACID, ...
Authors:Huang, J, Wan, B, Lei, M.
Deposit date:2011-10-16
Release date:2012-02-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
Nature, 482, 2012
5YAE
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BU of 5yae by Molmil
Ferulic acid esterase from Streptomyces cinnamoneus at 2.4 A resolution
Descriptor: ACETATE ION, Esterase, SULFATE ION
Authors:Tamura, H, Uraji, M, Mizohata, E, Ogawa, K, Inoue, T, Hatanaka, T.
Deposit date:2017-08-31
Release date:2017-12-06
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Loop of Streptomyces Feruloyl Esterase Plays an Important Role in the Enzyme's Catalyzing the Release of Ferulic Acid from Biomass.
Appl. Environ. Microbiol., 84, 2018
5YAL
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BU of 5yal by Molmil
Ferulic acid esterase from Streptomyces cinnamoneus at 1.5 A resolution
Descriptor: ACETATE ION, Esterase, GLYCEROL, ...
Authors:Tamura, H, Uraji, M, Mizohata, E, Ogawa, K, Inoue, T, Hatanaka, T.
Deposit date:2017-09-01
Release date:2017-12-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Loop of Streptomyces Feruloyl Esterase Plays an Important Role in the Enzyme's Catalyzing the Release of Ferulic Acid from Biomass.
Appl. Environ. Microbiol., 84, 2018
3WSU
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BU of 3wsu by Molmil
Crystal structure of beta-mannanase from Streptomyces thermolilacinus
Descriptor: Beta-mannanase, GLYCEROL, SODIUM ION
Authors:Kumagai, Y, Yamashita, K, Okuyama, M, Hatanaka, T, Yao, M, Kimura, A.
Deposit date:2014-03-26
Release date:2015-05-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The loop structure of Actinomycete glycoside hydrolase family 5 mannanases governs substrate recognition
Febs J., 282, 2015
6D2L
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BU of 6d2l by Molmil
Crystal structure of human CARM1 with (S)-SKI-72
Descriptor: (2S,5S)-2-amino-6-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-5-[(benzylamino)methyl]-N-[2-(4-hydroxyphenyl)ethyl]hexanamide, GLYCEROL, Histone-arginine methyltransferase CARM1, ...
Authors:DONG, A, ZENG, H, WALKER, J.R, Hutchinson, A, Seitova, A, LUO, M, CAI, X.C, KE, W, WANG, J, SHI, C, ZHENG, W, LEE, J.P, IBANEZ, G, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, WU, H, Structural Genomics Consortium (SGC)
Deposit date:2018-04-13
Release date:2018-05-23
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:A chemical probe of CARM1 alters epigenetic plasticity against breast cancer cell invasion.
Elife, 8, 2019
8WCT
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BU of 8wct by Molmil
The crystal structure of the CHASE4 domain of iron-sensetive membrane protein (IsmP,Uniprot ID:Q9I243)
Descriptor: Bifunctional diguanylate cyclase/phosphodiesterase, GLYCEROL
Authors:Wang, C.C.
Deposit date:2023-09-13
Release date:2024-02-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A c-di-GMP signaling module controls responses to iron in Pseudomonas aeruginosa.
Nat Commun, 15, 2024
4IKP
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BU of 4ikp by Molmil
Crystal structure of coactivator-associated arginine methyltransferase 1 with methylenesinefungin
Descriptor: (2S,5S)-2,6-diamino-5-{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}hexanoic acid, GLYCEROL, Histone-arginine methyltransferase CARM1, ...
Authors:Dong, A, Dombrovski, L, He, H, Ibanez, G, Wernimont, A, Zheng, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Luo, M, Wu, H, Structural Genomics Consortium (SGC)
Deposit date:2012-12-27
Release date:2013-02-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:A chemical probe of CARM1 alters epigenetic plasticity against breast cancer cell invasion.
Elife, 8, 2019
7PQX
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BU of 7pqx by Molmil
Structure of CtAtm1 in the inward-facing open conformation
Descriptor: Putative iron-sulfur protein
Authors:Li, P, Wang, K.T, Gourdon, P.E.
Deposit date:2021-09-20
Release date:2022-08-10
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Structures of Atm1 provide insight into [2Fe-2S] cluster export from mitochondria.
Nat Commun, 13, 2022

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