4M7C

Crystal structure of the TRF2-binding motif of SLX4 in complex with the TRFH domain of TRF2

Summary for 4M7C

• Entry DOI: 10.2210/pdb4m7c/pdb
• Related: 4M79
• Descriptor: Telomeric repeat-binding factor 2, Peptide from Structure-specific endonuclease subunit SLX4 (3 entities in total)
• Functional Keywords: telomere, t-loop, endonuclease, alt, transcription, endonuclease regulator, dna, hydrolase regulator
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q15554 Q8IY92
• Total number of polymer chains: 4
• Total formula weight: 49842.01

Authors

Wan, B.,Chen, Y.,Wu, J.,Liu, Y.,Lei, M. (deposition date: 2013-08-12, release date: 2013-09-25, Last modification date: 2023-11-08)

• Primary citation: Wan, B.,Yin, J.,Horvath, K.,Sarkar, J.,Chen, Y.,Wu, J.,Wan, K.,Lu, J.,Gu, P.,Yu, E.Y.,Lue, N.F.,Chang, S.,Liu, Y.,Lei, M.; SLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with Telomeres; Cell Rep, 4:861-869, 2013; PubMed: 24012755; DOI: 10.1016/j.celrep.2013.08.017

Experimental method

X-RAY DIFFRACTION (2.05 Å)