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4M7C

Crystal structure of the TRF2-binding motif of SLX4 in complex with the TRFH domain of TRF2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Telomeric repeat-binding factor 2polymer20023410.32UniProt (Q15554)
Pfam (PF08558)
Homo sapiens (human)TTAGGG repeat-binding factor 2, Telomeric DNA-binding protein
2C, D
(C, D)
Peptide from Structure-specific endonuclease subunit SLX4polymer131510.72UniProt (Q8IY92)Homo sapiens (human)BTB/POZ domain-containing protein 12
3E, F, G, H
(A, B, C, D)
waterwater18.0271Chemie (HOH)
Sequence modifications
C, D: 498 - 509 (UniProt: Q8IY92)
PDBExternal DatabaseDetails
Ser 497-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight49842.0
All*Total formula weight49842.0
*Water molecules are not included.

226707

PDB entries from 2024-10-30

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