1Q1J
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![BU of 1q1j by Molmil](/molmil-images/mine/1q1j) | Crystal Structure Analysis of anti-HIV-1 Fab 447-52D in complex with V3 peptide | 分子名称: | Fab 447-52D, heavy chain, light chain, ... | 著者 | Stanfield, R.L, Gorny, M.K, Williams, C, Zolla-Pazner, S, Wilson, I.A. | 登録日 | 2003-07-21 | 公開日 | 2004-02-17 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural rationale for the broad neutralization of HIV-1 by human monoclonal antibody 447-52D. Structure, 12, 2004
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1NIZ
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![BU of 1niz by Molmil](/molmil-images/mine/1niz) | NMR structure of a V3 (MN isolate) peptide bound to 447-52D, a human HIV-1 neutralizing antibody | 分子名称: | Exterior membrane glycoprotein(GP120) | 著者 | Sharon, M, Kessler, N, Levy, R, Zolla-Pazner, S, Gorlach, M, Anglister, J. | 登録日 | 2002-12-30 | 公開日 | 2003-02-25 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Alternative Conformations of HIV-1 V3 Loops Mimic
beta Hairpins in Chemokines, Suggesting a Mechanism
for Coreceptor Selectivity. Structure, 11, 2003
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1NJ0
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![BU of 1nj0 by Molmil](/molmil-images/mine/1nj0) | NMR structure of a V3 (MN isolate) peptide bound to 447-52D, a human HIV-1 neutralizing antibody | 分子名称: | Exterior membrane glycoprotein(GP120) | 著者 | Sharon, M, Kessler, N, Levy, R, Zolla-Pazner, S, Gorlach, M, Anglister, J. | 登録日 | 2002-12-30 | 公開日 | 2003-02-25 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Alternative Conformations of HIV-1 V3 Loops Mimic
beta Hairpins in Chemokines, Suggesting a Mechanism
for Coreceptor Selectivity. Structure, 11, 2003
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3PIQ
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![BU of 3piq by Molmil](/molmil-images/mine/3piq) | Crystal structure of human 2909 Fab, a quaternary structure-specific antibody against HIV-1 | 分子名称: | Human monoclonal antibody 2909 Fab heavy chain, Human monoclonal antibody 2909 Fab light chain | 著者 | Changela, A, Gorny, M.K, Zolla-Pazner, S, Kwong, P.D. | 登録日 | 2010-11-07 | 公開日 | 2011-01-05 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.325 Å) | 主引用文献 | Crystal Structure of Human Antibody 2909 Reveals Conserved Features of Quaternary Structure-Specific Antibodies That Potently Neutralize HIV-1. J.Virol., 85, 2011
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1U6V
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![BU of 1u6v by Molmil](/molmil-images/mine/1u6v) | NMR structure of a V3 (IIIB isolate) peptide bound to 447-52D, a human HIV-1 neutralizing antibody | 分子名称: | V3 peptide | 著者 | Rosen, O, Chill, J, Sharon, M, Kessler, N, Mester, B, Zolla-Pazner, S, Anglister, J. | 登録日 | 2004-08-02 | 公開日 | 2005-04-05 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Induced fit in HIV-neutralizing antibody complexes: evidence for alternative conformations of the gp120 V3 loop and the molecular basis for broad neutralization. Biochemistry, 44, 2005
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3P30
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![BU of 3p30 by Molmil](/molmil-images/mine/3p30) | crystal structure of the cluster II Fab 1281 in complex with HIV-1 gp41 ectodomain | 分子名称: | 1281 Fab heavy chain, 1281 Fab light chain, HIV-1 gp41 | 著者 | Frey, G, Chen, J, Rits-Volloch, S, Freeman, M.M, Zolla-Pazner, S, Chen, B. | 登録日 | 2010-10-04 | 公開日 | 2010-11-17 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Distinct conformational states of HIV-1 gp41 are recognized by neutralizing and non-neutralizing antibodies. Nat.Struct.Mol.Biol., 17, 2010
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1U6U
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![BU of 1u6u by Molmil](/molmil-images/mine/1u6u) | NMR structure of a V3 (IIIB isolate) peptide bound to 447-52D, a human HIV-1 neutralizing antibody | 分子名称: | V3 peptide | 著者 | Rosen, O, Chill, J, Sharon, M, Kessler, N, Mester, B, Zolla-Pazner, S, Anglister, J. | 登録日 | 2004-08-02 | 公開日 | 2005-04-05 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Induced fit in HIV-neutralizing antibody complexes: evidence for alternative conformations of the gp120 V3 loop and the molecular basis for broad neutralization. Biochemistry, 44, 2005
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2B1A
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![BU of 2b1a by Molmil](/molmil-images/mine/2b1a) | Crystal structure analysis of anti-HIV-1 V3 Fab 2219 in complex with UG1033 peptide | 分子名称: | Fab 2219, heavy chain, light chain, ... | 著者 | Stanfield, R.L, Gorny, M.K, Zolla-Pazner, S, Wilson, I.A. | 登録日 | 2005-09-15 | 公開日 | 2006-07-04 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.348 Å) | 主引用文献 | Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity. J.Virol., 80, 2006
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2B1H
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![BU of 2b1h by Molmil](/molmil-images/mine/2b1h) | Crystal structure analysis of anti-HIV-1 V3 Fab 2219 in complex with UG29 peptide | 分子名称: | Fab 2219, heavy chain, light chain, ... | 著者 | Stanfield, R.L, Gorny, M.K, Zolla-Pazner, S, Wilson, I.A. | 登録日 | 2005-09-15 | 公開日 | 2006-07-04 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity. J.Virol., 80, 2006
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2B0S
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![BU of 2b0s by Molmil](/molmil-images/mine/2b0s) | Crystal structure analysis of anti-HIV-1 V3 Fab 2219 in complex with MN peptide | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, Fab 2219, ... | 著者 | Stanfield, R.L, Gorny, M.K, Zolla-Pazner, S, Wilson, I.A. | 登録日 | 2005-09-14 | 公開日 | 2006-07-04 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity. J.Virol., 80, 2006
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3Q6G
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![BU of 3q6g by Molmil](/molmil-images/mine/3q6g) | Crystal structure of Fab of rhesus mAb 2.5B specific for quaternary neutralizing epitope of HIV-1 gp120 | 分子名称: | Heavy chain of Fab of rhesus mAb 2.5B, Light chain of Fab of rhesus mAb 2.5B | 著者 | Spurrier, B, Sampson, J, Totrov, M, Li, H, O'Neal, T, William, C, Robinson, J, Gorny, M.K, Zolla-Pazner, S, Kong, X.P. | 登録日 | 2010-12-31 | 公開日 | 2011-05-25 | 最終更新日 | 2013-03-20 | 実験手法 | X-RAY DIFFRACTION (1.902 Å) | 主引用文献 | Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120. Structure, 19, 2011
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3Q6F
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![BU of 3q6f by Molmil](/molmil-images/mine/3q6f) | Crystal structure of Fab of human mAb 2909 specific for quaternary neutralizing epitope of HIV-1 gp120 | 分子名称: | DI(HYDROXYETHYL)ETHER, Heavy chain of Fab of human mAb 2909, Light chain of Fab of human mAb 2909 | 著者 | Spurrier, B, Sampson, J, Totrov, M, Li, H, O'Neal, T, William, C, Robinson, J, Gorny, M.K, Zolla-Pazner, S, Kong, X.P. | 登録日 | 2010-12-31 | 公開日 | 2011-05-25 | 最終更新日 | 2011-10-12 | 実験手法 | X-RAY DIFFRACTION (3.192 Å) | 主引用文献 | Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120. Structure, 19, 2011
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7LY9
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![BU of 7ly9 by Molmil](/molmil-images/mine/7ly9) | |
3C2A
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![BU of 3c2a by Molmil](/molmil-images/mine/3c2a) | Antibody Fab fragment 447-52D in complex with UG1033 peptide | 分子名称: | Envelope glycoprotein, Fab 447-52D heavy chain, Fab 447-52D light chain | 著者 | Dhillon, A.K, Stanfield, R.L, Wilson, I.A. | 登録日 | 2008-01-24 | 公開日 | 2008-07-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure determination of an anti-HIV-1 Fab 447-52D-peptide complex from an epitaxially twinned data set Acta Crystallogr.,Sect.D, 64, 2008
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4HQQ
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![BU of 4hqq by Molmil](/molmil-images/mine/4hqq) | |
4HPY
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![BU of 4hpy by Molmil](/molmil-images/mine/4hpy) | Crystal structure of RV144-elicited antibody CH59 in complex with V2 peptide | 分子名称: | CH59 Fab heavy chain, CH59 Fab light chain, Envelope glycoprotein gp160, ... | 著者 | McLellan, J.S, Gorman, J, Haynes, B.F, Kwong, P.D. | 登録日 | 2012-10-24 | 公開日 | 2013-02-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2. Immunity, 38, 2013
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4HPO
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![BU of 4hpo by Molmil](/molmil-images/mine/4hpo) | Crystal structure of RV144-elicited antibody CH58 in complex with V2 peptide | 分子名称: | CH58 Fab heavy chain, CH58 Fab light chain, Envelope glycoprotein gp160, ... | 著者 | McLellan, J.S, Gorman, J, Haynes, B.F, Kwong, P.D. | 登録日 | 2012-10-24 | 公開日 | 2013-02-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.694 Å) | 主引用文献 | Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2. Immunity, 38, 2013
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4D9L
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![BU of 4d9l by Molmil](/molmil-images/mine/4d9l) | Fab structure of anti-HIV-1 gp120 V2 mAb 697 | 分子名称: | Heavy chain of Fab fragment of anti-HIV1 gp120 V2 mAb 697, Light chain of Fab fragment of anti-HIV1 gp120 V2 mAb 697 | 著者 | Pan, R.M, Kong, X.P. | 登録日 | 2012-01-11 | 公開日 | 2012-03-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.485 Å) | 主引用文献 | Functional and immunochemical cross-reactivity of V2-specific monoclonal antibodies from HIV-1-infected individuals. Virology, 427, 2012
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4ZMJ
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![BU of 4zmj by Molmil](/molmil-images/mine/4zmj) | Crystal Structure of Ligand-Free BG505 SOSIP.664 HIV-1 Env Trimer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | 著者 | Kwon, Y.D, Kwong, P.D. | 登録日 | 2015-05-04 | 公開日 | 2015-06-24 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | 主引用文献 | Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env. Nat.Struct.Mol.Biol., 22, 2015
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8D5C
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![BU of 8d5c by Molmil](/molmil-images/mine/8d5c) | anti-HIV-1 gp120-sCD4 complex antibody CG10 Fab in complex with B41-sCD4 | 分子名称: | CG10 Fab heavy chain, CG10 Fab light chain, Envelope glycoprotein gp160, ... | 著者 | Yang, Z, Bjorkman, P.J, Gershoni, J.M. | 登録日 | 2022-06-04 | 公開日 | 2022-11-16 | 最終更新日 | 2023-01-04 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Antibody Recognition of CD4-Induced Open HIV-1 Env Trimers. J.Virol., 96, 2022
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8D54
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![BU of 8d54 by Molmil](/molmil-images/mine/8d54) | |
4XMK
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![BU of 4xmk by Molmil](/molmil-images/mine/4xmk) | |
4XML
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![BU of 4xml by Molmil](/molmil-images/mine/4xml) | |
4M1D
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![BU of 4m1d by Molmil](/molmil-images/mine/4m1d) | |
4OAW
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![BU of 4oaw by Molmil](/molmil-images/mine/4oaw) | Fab structure of anti-HIV gp120 V2 mAb 2158 | 分子名称: | GLYCEROL, Heavy chain of Fab fragment of anti-HIV1 gp120 V2 mAb 2158, Light chain of Fab fragment of anti-HIV1 gp120 V2 mAb 2158, ... | 著者 | Spurrier, B.R, Kong, X.P. | 登録日 | 2014-01-06 | 公開日 | 2014-03-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Functional Implications of the Binding Mode of a Human Conformation-Dependent V2 Monoclonal Antibody against HIV. J.Virol., 88, 2014
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