3P30

crystal structure of the cluster II Fab 1281 in complex with HIV-1 gp41 ectodomain

Summary for 3P30

Entry DOI	10.2210/pdb3p30/pdb
Descriptor	HIV-1 gp41, 1281 Fab light chain, 1281 Fab heavy chain (3 entities in total)
Functional Keywords	hiv, gp41, cluster 2, fab, 6-helix bundle, immune system
Biological source	Human immunodeficiency virus 1 More
Total number of polymer chains	3
Total formula weight	57777.54
Authors	Frey, G.,Chen, J.,Rits-Volloch, S.,Freeman, M.M.,Zolla-Pazner, S.,Chen, B. (deposition date: 2010-10-04, release date: 2010-11-17, Last modification date: 2017-11-08)
Primary citation	Frey, G.,Chen, J.,Rits-Volloch, S.,Freeman, M.M.,Zolla-Pazner, S.,Chen, B. Distinct conformational states of HIV-1 gp41 are recognized by neutralizing and non-neutralizing antibodies. Nat.Struct.Mol.Biol., 17:1486-1491, 2010 Cited by PubMed: 21076402 DOI: 10.1038/nsmb.1950 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation