8YLB
| Cocrystal structures of agonists compound 1 with HsClpP | 分子名称: | 5-[(2-methylphenyl)methyl]-11-(phenylmethyl)-2,5,7,11-tetrazatricyclo[7.4.0.0^{2,6}]trideca-1(9),6-dien-8-one, ATP-dependent Clp protease proteolytic subunit, mitochondrial | 著者 | Zhao, N, Zhu, Y, Bao, R. | 登録日 | 2024-03-06 | 公開日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Rational Design of a Novel Class of Human ClpP Agonists through a Ring-Opening Strategy with Enhanced Antileukemia Activity. J.Med.Chem., 67, 2024
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1J4J
| Crystal Structure of Tabtoxin Resistance Protein (form II) complexed with an Acyl Coenzyme A | 分子名称: | ACETYL COENZYME *A, TABTOXIN RESISTANCE PROTEIN | 著者 | He, H, Ding, Y, Bartlam, M, Zhang, R, Duke, N, Joachimiak, A, Shao, Y, Cao, Z, Tang, H, Liu, Y, Jiang, F, Liu, J, Zhao, N, Rao, Z. | 登録日 | 2001-10-02 | 公開日 | 2003-06-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Crystal structure of tabtoxin resistance protein complexed with acetyl coenzyme A reveals the mechanism for beta-lactam acetylation. J.Mol.Biol., 325, 2003
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1GHE
| CRYSTAL STRUCTURE OF TABTOXIN RESISTANCE PROTEIN COMPLEXED WITH AN ACYL COENZYME A | 分子名称: | ACETYL COENZYME *A, ACETYLTRANSFERASE | 著者 | He, H, Ding, Y, Bartlam, M, Sun, F, Le, Y, Qin, X, Tang, H, Zhang, R, Joachimiak, A, Liu, Y, Zhao, N, Rao, Z. | 登録日 | 2000-12-13 | 公開日 | 2003-01-14 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal Structure of Tabtoxin Resistance Protein Complexed with Acetyl
Coenzyme A Reveals the Mechanism for beta-Lactam Acetylation J.Mol.Biol., 325, 2003
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7BOR
| Structure of Pseudomonas aeruginosa CoA-bound OdaA | 分子名称: | COENZYME A, Probable enoyl-CoA hydratase/isomerase | 著者 | Zhao, N, Zhao, C, Liu, L, Li, T, Li, C, He, L, Zhu, Y, Song, Y, Bao, R. | 登録日 | 2020-03-19 | 公開日 | 2020-05-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | 主引用文献 | Structural and molecular dynamic studies of Pseudomonas aeruginosa OdaA reveal the regulation role of a C-terminal hinge element. Biochim Biophys Acta Gen Subj, 1865, 2020
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3B5I
| Crystal structure of Indole-3-acetic Acid Methyltransferase | 分子名称: | MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, S-adenosyl-L-methionine:salicylic acid carboxyl methyltransferase-like protein | 著者 | Ferrer, J.-L, Noel, J.P. | 登録日 | 2007-10-26 | 公開日 | 2008-01-15 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural, Biochemical, and Phylogenetic Analyses Suggest That Indole-3-Acetic Acid Methyltransferase Is an Evolutionarily Ancient Member of the SABATH Family. Plant Physiol., 146, 2008
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8JU7
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7CRD
| Structure of Pseudomonas aeruginosa OdaA | 分子名称: | Probable enoyl-CoA hydratase/isomerase | 著者 | Zhao, N, Zhao, C, Liu, L, Li, T, Li, C, He, L, Zhu, Y, Song, Y, Bao, R. | 登録日 | 2020-08-13 | 公開日 | 2020-09-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | 主引用文献 | Structural and molecular dynamic studies of Pseudomonas aeruginosa OdaA reveal the regulation role of a C-terminal hinge element. Biochim Biophys Acta Gen Subj, 1865, 2020
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7URL
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7BOV
| The Structure of Bacillus subtilis glycosyltransferase,Bs-YjiC | 分子名称: | GLYCEROL, SODIUM ION, Uncharacterized UDP-glucosyltransferase YjiC | 著者 | Zhao, C, Liu, B, Zhao, N.L, Luo, Y.Z, Bao, R. | 登録日 | 2020-03-20 | 公開日 | 2020-05-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.293 Å) | 主引用文献 | Structural and biochemical studies of the glycosyltransferase Bs-YjiC from Bacillus subtilis. Int.J.Biol.Macromol., 166, 2021
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6JAU
| The complex structure of Pseudomonas aeruginosa MucA/MucB. | 分子名称: | CALCIUM ION, GLYCEROL, HEXAETHYLENE GLYCOL, ... | 著者 | Li, T, He, L.H, Li, C.C, Liu, L, Peng, C.T, Shen, Y.L, Qin, X.F, Xiao, Q.J, Zhu, Y.B, Song, Y.J, Zhao, N.l, Zhao, C, Yang, J, Mu, X.Y, Huang, Q, Bao, R. | 登録日 | 2019-01-25 | 公開日 | 2020-01-29 | 最終更新日 | 2020-08-19 | 実験手法 | X-RAY DIFFRACTION (1.905 Å) | 主引用文献 | Molecular basis of the lipid-induced MucA-MucB dissociation in Pseudomonas aeruginosa. Commun Biol, 3, 2020
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7X8X
| structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications for developing antimicrobial agents targeting Clp protease | 分子名称: | 4-[1-[3-[4-[(4-fluoranyl-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-quinazolin-7-yl]oxypropyl]piperidin-4-yl]benzamide, 4-[[3,5-bis(fluoranyl)phenyl]methyl]-N-[(4-bromophenyl)methyl]piperazine-1-carboxamide, ATP-dependent Clp protease proteolytic subunit 1, ... | 著者 | Bao, R, Luo, Y.F, Zhu, Y.B, Yang, Y, Zhou, Y.Z. | 登録日 | 2022-03-15 | 公開日 | 2023-04-12 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (3.24 Å) | 主引用文献 | Discovery and Mechanistic Study of Novel Mycobacterium tuberculosis ClpP1P2 Inhibitors J.Med.Chem., 66, 2023
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8I60
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6M2L
| Crystal structure of Plasmodium falciparum hexose transporter PfHT1 bound with C3361 | 分子名称: | (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol, Hexose transporter 1 | 著者 | Jiang, X, Yuan, Y.Y, Zhang, S, Wang, N, Yan, C.Y, Yan, N. | 登録日 | 2020-02-27 | 公開日 | 2020-09-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Structural Basis for Blocking Sugar Uptake into the Malaria Parasite Plasmodium falciparum. Cell, 183, 2020
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6M20
| Crystal structure of Plasmodium falciparum hexose transporter PfHT1 bound with glucose | 分子名称: | Hexose transporter 1, beta-D-glucopyranose, nonyl beta-D-glucopyranoside | 著者 | Jiang, X, Yuan, Y.Y, Zhang, S, Wang, N, Yan, C.Y, Yan, N. | 登録日 | 2020-02-26 | 公開日 | 2020-09-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural Basis for Blocking Sugar Uptake into the Malaria Parasite Plasmodium falciparum. Cell, 183, 2020
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5YEI
| Mechanistic insight into the regulation of Pseudomonas aeruginosa aspartate kinase | 分子名称: | Aspartokinase, GLYCEROL, LYSINE, ... | 著者 | Li, C, Yang, M, Liu, L, Peng, C, Li, T, He, L, Song, Y, Zhu, Y, Bao, R. | 登録日 | 2017-09-17 | 公開日 | 2018-08-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Mechanistic insights into the allosteric regulation of Pseudomonas aeruginosa aspartate kinase. Biochem.J., 475, 2018
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8KHG
| Itaconyl-CoA hydratase PaIch | 分子名称: | CITRIC ACID, Itaconyl-CoA hydratase | 著者 | Huang, Q, Bao, R. | 登録日 | 2023-08-21 | 公開日 | 2024-05-15 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural and functional characterization of itaconyl-CoA hydratase and citramalyl-CoA lyase involved in itaconate metabolism of Pseudomonas aeruginosa. Structure, 32, 2024
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8KHL
| (S)-citramalyl-CoA lyase | 分子名称: | COENZYME A, Probable acyl-CoA lyase beta chain | 著者 | Huang, Q, Bao, R. | 登録日 | 2023-08-22 | 公開日 | 2024-05-15 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and functional characterization of itaconyl-CoA hydratase and citramalyl-CoA lyase involved in itaconate metabolism of Pseudomonas aeruginosa. Structure, 32, 2024
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8WCO
| (S)-citramalyl-CoA lyase | 分子名称: | ACETYL COENZYME *A, Probable acyl-CoA lyase beta chain | 著者 | Huang, Q, Bao, R. | 登録日 | 2023-09-13 | 公開日 | 2024-05-15 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural and functional characterization of itaconyl-CoA hydratase and citramalyl-CoA lyase involved in itaconate metabolism of Pseudomonas aeruginosa. Structure, 32, 2024
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7CO3
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7CO2
| HtrA-type protease AlgW with tripeptide | 分子名称: | AlgW protein, IMIDAZOLE, TRP-VAL-PHE | 著者 | Li, T, Song, Y.J, Bao, R. | 登録日 | 2020-08-03 | 公開日 | 2021-03-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Molecular Basis of the Versatile Regulatory Mechanism of HtrA-Type Protease AlgW from Pseudomonas aeruginosa. Mbio, 12, 2021
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7CO5
| HtrA-type protease AlgW with decapeptide | 分子名称: | AlgW protein, IMIDAZOLE, decapeptide SVRDELRWVF | 著者 | Li, T, Song, Y.J, Bao, R. | 登録日 | 2020-08-03 | 公開日 | 2021-03-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.345 Å) | 主引用文献 | Molecular Basis of the Versatile Regulatory Mechanism of HtrA-Type Protease AlgW from Pseudomonas aeruginosa. Mbio, 12, 2021
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7CO7
| HtrA-type protease AlgWS227A with decapeptide | 分子名称: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, AlgW protein, decapeptide SVRDELRWVF | 著者 | Li, T, Song, Y.J, Bao, R. | 登録日 | 2020-08-04 | 公開日 | 2021-03-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Molecular Basis of the Versatile Regulatory Mechanism of HtrA-Type Protease AlgW from Pseudomonas aeruginosa. Mbio, 12, 2021
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7CSW
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7CSV
| Pseudomonas aeruginosa antitoxin HigA | 分子名称: | HTH cro/C1-type domain-containing protein | 著者 | Song, Y.J, Luo, G.H, Bao, R. | 登録日 | 2020-08-17 | 公開日 | 2021-01-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Pseudomonas aeruginosa antitoxin HigA functions as a diverse regulatory factor by recognizing specific pseudopalindromic DNA motifs. Environ.Microbiol., 23, 2021
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7CSY
| Pseudomonas aeruginosa antitoxin HigA with higBA promoter | 分子名称: | DNA (28-MER), DNA (29-MER), HTH cro/C1-type domain-containing protein, ... | 著者 | Song, Y.J, Luo, G.H, Bao, R. | 登録日 | 2020-08-17 | 公開日 | 2021-01-13 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Pseudomonas aeruginosa antitoxin HigA functions as a diverse regulatory factor by recognizing specific pseudopalindromic DNA motifs. Environ.Microbiol., 23, 2021
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