5ZNL
| Crystal structure of PDE10A catalytic domain complexed with LHB-6 | 分子名称: | MAGNESIUM ION, N-[2-(7-methoxy-4-morpholin-4-yl-quinazolin-6-yl)oxyethyl]-1,3-benzothiazol-2-amine, ZINC ION, ... | 著者 | Li, Z, Huang, Y, Zhan, C.G, Luo, H.B. | 登録日 | 2018-04-09 | 公開日 | 2019-02-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Absolute Binding Free Energy Calculation and Design of a Subnanomolar Inhibitor of Phosphodiesterase-10. J. Med. Chem., 62, 2019
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4P08
| Engineered thermostable dimeric cocaine esterase | 分子名称: | Cocaine esterase | 著者 | Rodgers, D.W, Chow, K.-M, Fang, L, Zhan, C.-G. | 登録日 | 2014-02-20 | 公開日 | 2014-07-16 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.341 Å) | 主引用文献 | Rational design, preparation, and characterization of a therapeutic enzyme mutant with improved stability and function for cocaine detoxification. Acs Chem.Biol., 9, 2014
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5YWG
| Crystal structure of Arabidopsis thaliana HPPD complexed with Mesotrione | 分子名称: | 2-[(4-methylsulfonyl-2-nitro-phenyl)-oxidanyl-methylidene]cyclohexane-1,3-dione, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | 著者 | Lin, H.Y, Yang, W.C. | 登録日 | 2017-11-29 | 公開日 | 2019-01-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.603 Å) | 主引用文献 | Molecular insights into the mechanism of 4-hydroxyphenylpyruvate dioxygenase inhibition: enzyme kinetics, X-ray crystallography and computational simulations. FEBS J., 286, 2019
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5YY6
| Crystal structure of Arabidopsis thaliana HPPD truncated mutant complexed with Benquitrione | 分子名称: | 3-(2,6-dimethylphenyl)-1-methyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-quinazoline-2,4-dione, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | 著者 | Yang, W.C, Chen, J.N, Yang, G.F. | 登録日 | 2017-12-08 | 公開日 | 2019-01-16 | 最終更新日 | 2019-10-09 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | Crystal Structure of 4-Hydroxyphenylpyruvate Dioxygenase in Complex with Substrate Reveals a New Starting Point for Herbicide Discovery. Research (Wash D C), 2019, 2019
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5XGK
| Crystal structure of Arabidopsis thaliana 4-hydroxyphenylpyruvate dioxygenase (AtHPPD) complexed with its substrate 4-hydroxyphenylpyruvate acid (HPPA) | 分子名称: | (2S)-2-hydroxy-3-(4-hydroxyphenyl)propanoic acid, 4-hydroxyphenylpyruvate dioxygenase, ACETATE ION, ... | 著者 | Yang, G.F, Yang, W.C, Lin, H.Y. | 登録日 | 2017-04-14 | 公開日 | 2018-09-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of 4-Hydroxyphenylpyruvate Dioxygenase in Complex with Substrate Reveals a New Starting Point for Herbicide Discovery. Res, 2019, 2019
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6N04
| The X-ray crystal structure of AbsH3, an FAD dependent reductase from the Abyssomicin biosynthesis pathway in Streptomyces | 分子名称: | AbsH3, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Clinger, J.A, Wang, X, Cai, W, Miller, M.D, Van Lanen, S.G, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2018-11-06 | 公開日 | 2019-11-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | 主引用文献 | The crystal structure of AbsH3: A putative flavin adenine dinucleotide-dependent reductase in the abyssomicin biosynthesis pathway. Proteins, 2020
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4R99
| Crystal structure of a uricase from Bacillus fastidious | 分子名称: | SULFATE ION, Uricase | 著者 | Feng, J, Wang, L, Liu, H.B, Liu, L, Liao, F. | 登録日 | 2014-09-03 | 公開日 | 2015-05-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of Bacillus fastidious uricase reveals an unexpected folding of the C-terminus residues crucial for thermostability under physiological conditions. Appl.Microbiol.Biotechnol., 99, 2015
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4R8X
| Crystal structure of a uricase from Bacillus fastidious | 分子名称: | Uricase | 著者 | Feng, J, Wang, L, Liu, H.B, Liu, L, Liao, F. | 登録日 | 2014-09-03 | 公開日 | 2015-05-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.401 Å) | 主引用文献 | Crystal structure of Bacillus fastidious uricase reveals an unexpected folding of the C-terminus residues crucial for thermostability under physiological conditions. Appl.Microbiol.Biotechnol., 99, 2015
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3I2G
| Cocaine Esterase with mutation G173Q, bound to DTT adduct | 分子名称: | (4S,5S)-4,5-BIS(MERCAPTOMETHYL)-1,3-DIOXOLAN-2-OL, CHLORIDE ION, Cocaine esterase, ... | 著者 | Tesmer, J.J.G, Nance, M.R. | 登録日 | 2009-06-29 | 公開日 | 2010-06-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural analysis of thermostabilizing mutations of cocaine esterase. Protein Eng.Des.Sel., 23, 2010
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3I2K
| Cocaine Esterase, wild type, bound to a DTT adduct | 分子名称: | (4S,5S)-4,5-BIS(MERCAPTOMETHYL)-1,3-DIOXOLAN-2-OL, CHLORIDE ION, Cocaine esterase, ... | 著者 | Tesmer, J.J.G, Nance, M.R. | 登録日 | 2009-06-29 | 公開日 | 2010-06-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Structural analysis of thermostabilizing mutations of cocaine esterase. Protein Eng.Des.Sel., 23, 2010
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3I2F
| Cocaine Esterase with mutations T172R / G173Q, bound to DTT adduct | 分子名称: | (4S,5S)-4,5-BIS(MERCAPTOMETHYL)-1,3-DIOXOLAN-2-OL, CHLORIDE ION, Cocaine esterase, ... | 著者 | Tesmer, J.J.G, Nance, M.R. | 登録日 | 2009-06-29 | 公開日 | 2010-06-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural analysis of thermostabilizing mutations of cocaine esterase. Protein Eng.Des.Sel., 23, 2010
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3IDA
| Thermostable Cocaine Esterase with mutations L169K and G173Q, bound to DTT adduct | 分子名称: | (4S,5S)-4,5-BIS(MERCAPTOMETHYL)-1,3-DIOXOLAN-2-OL, CHLORIDE ION, Cocaine esterase, ... | 著者 | Tesmer, J.J.G, Nance, M.R. | 登録日 | 2009-07-20 | 公開日 | 2010-03-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A thermally stable form of bacterial cocaine esterase: a potential therapeutic agent for treatment of cocaine abuse. Mol.Pharmacol., 77, 2010
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3I2H
| Cocaine Esterase with mutation L169K, bound to DTT adduct | 分子名称: | (4S,5S)-4,5-BIS(MERCAPTOMETHYL)-1,3-DIOXOLAN-2-OL, CHLORIDE ION, Cocaine esterase, ... | 著者 | Tesmer, J.J.G, Nance, M.R. | 登録日 | 2009-06-29 | 公開日 | 2010-06-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural analysis of thermostabilizing mutations of cocaine esterase. Protein Eng.Des.Sel., 23, 2010
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3I2J
| Cocaine Esterase, wild type, without a ligand | 分子名称: | CHLORIDE ION, Cocaine esterase, GLYCEROL, ... | 著者 | Tesmer, J.J.G, Nance, M.R. | 登録日 | 2009-06-29 | 公開日 | 2010-06-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Structural analysis of thermostabilizing mutations of cocaine esterase. Protein Eng.Des.Sel., 23, 2010
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3I2I
| Cocaine Esterase with mutation T172R, bound to DTT adduct | 分子名称: | (4S,5S)-4,5-BIS(MERCAPTOMETHYL)-1,3-DIOXOLAN-2-OL, CHLORIDE ION, Cocaine esterase, ... | 著者 | Tesmer, J.J.G, Nance, M.R. | 登録日 | 2009-06-29 | 公開日 | 2010-06-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Structural analysis of thermostabilizing mutations of cocaine esterase. Protein Eng.Des.Sel., 23, 2010
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7E0X
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6ISD
| Crystal structure of Arabidopsis thaliana HPPD complexed with sulcotrione | 分子名称: | 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | 著者 | Yang, W.C, Yang, G.F. | 登録日 | 2018-11-16 | 公開日 | 2018-11-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Molecular insights into the mechanism of 4-hydroxyphenylpyruvate dioxygenase inhibition: enzyme kinetics, X-ray crystallography and computational simulations. FEBS J., 286, 2019
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6J63
| Crystal structure of Arabidopsis thaliana HPPD complexed with NTBC | 分子名称: | 2-{HYDROXY[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]METHYLENE}CYCLOHEXANE-1,3-DIONE, 4-hydroxyphenylpyruvate dioxygenase, FE (III) ION | 著者 | Yang, W.C, Yang, G.F. | 登録日 | 2019-01-13 | 公開日 | 2019-02-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.624 Å) | 主引用文献 | Molecular insights into the mechanism of 4-hydroxyphenylpyruvate dioxygenase inhibition: enzyme kinetics, X-ray crystallography and computational simulations. FEBS J., 286, 2019
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