5XGK

Crystal structure of Arabidopsis thaliana 4-hydroxyphenylpyruvate dioxygenase (AtHPPD) complexed with its substrate 4-hydroxyphenylpyruvate acid (HPPA)

Summary for 5XGK

Entry DOI	10.2210/pdb5xgk/pdb
Related	1SP9
Descriptor	4-hydroxyphenylpyruvate dioxygenase, (2S)-2-hydroxy-3-(4-hydroxyphenyl)propanoic acid, FE (III) ION, ... (5 entities in total)
Functional Keywords	4-hydroxyphenylpyruvate dioxygenase, catalytic mechanism, drug discovery, oxidoreductase
Biological source	Arabidopsis thaliana (Mouse-ear cress)
Total number of polymer chains	4
Total formula weight	196137.06
Authors	Yang, G.F.,Yang, W.C.,Lin, H.Y. (deposition date: 2017-04-14, release date: 2018-09-19, Last modification date: 2023-11-22)
Primary citation	Lin, H.Y.,Chen, X.,Chen, J.N.,Wang, D.W.,Wu, F.X.,Lin, S.Y.,Zhan, C.G.,Wu, J.W.,Yang, W.C.,Yang, G.F. Crystal Structure of 4-Hydroxyphenylpyruvate Dioxygenase in Complex with Substrate Reveals a New Starting Point for Herbicide Discovery. Res, 2019:2602414-2602414, 2019 Cited by PubMed: 31549053 DOI: 10.34133/2019/2602414 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation