3IDA
Thermostable Cocaine Esterase with mutations L169K and G173Q, bound to DTT adduct
Summary for 3IDA
Entry DOI | 10.2210/pdb3ida/pdb |
Related | 3I2I 3i2g 3i2j 3i2k |
Descriptor | Cocaine esterase, CHLORIDE ION, (4S,5S)-4,5-BIS(MERCAPTOMETHYL)-1,3-DIOXOLAN-2-OL, ... (5 entities in total) |
Functional Keywords | alpha/beta hydrolase, esterase, hydrolase |
Biological source | Rhodococcus sp. |
Cellular location | Cytoplasm (Probable): Q9L9D7 |
Total number of polymer chains | 1 |
Total formula weight | 64822.57 |
Authors | Tesmer, J.J.G.,Nance, M.R. (deposition date: 2009-07-20, release date: 2010-03-02, Last modification date: 2023-09-06) |
Primary citation | Brim, R.L.,Nance, M.R.,Youngstrom, D.W.,Narasimhan, D.,Zhan, C.G.,Tesmer, J.J.,Sunahara, R.K.,Woods, J.H. A thermally stable form of bacterial cocaine esterase: a potential therapeutic agent for treatment of cocaine abuse. Mol.Pharmacol., 77:593-600, 2010 Cited by PubMed: 20086035DOI: 10.1124/mol.109.060806 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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