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3IDA

Thermostable Cocaine Esterase with mutations L169K and G173Q, bound to DTT adduct

Summary for 3IDA
Entry DOI10.2210/pdb3ida/pdb
Related3I2I 3i2g 3i2j 3i2k
DescriptorCocaine esterase, CHLORIDE ION, (4S,5S)-4,5-BIS(MERCAPTOMETHYL)-1,3-DIOXOLAN-2-OL, ... (5 entities in total)
Functional Keywordsalpha/beta hydrolase, esterase, hydrolase
Biological sourceRhodococcus sp.
Cellular locationCytoplasm (Probable): Q9L9D7
Total number of polymer chains1
Total formula weight64822.57
Authors
Tesmer, J.J.G.,Nance, M.R. (deposition date: 2009-07-20, release date: 2010-03-02, Last modification date: 2023-09-06)
Primary citationBrim, R.L.,Nance, M.R.,Youngstrom, D.W.,Narasimhan, D.,Zhan, C.G.,Tesmer, J.J.,Sunahara, R.K.,Woods, J.H.
A thermally stable form of bacterial cocaine esterase: a potential therapeutic agent for treatment of cocaine abuse.
Mol.Pharmacol., 77:593-600, 2010
Cited by
PubMed: 20086035
DOI: 10.1124/mol.109.060806
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

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