6R9T
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![BU of 6r9t by Molmil](/molmil-images/mine/6r9t) | Cryo-EM structure of autoinhibited human talin-1 | 分子名称: | Talin-1 | 著者 | Dedden, D, Schumacher, S, Zacharias, M, Biertumpfel, C, Mizuno, N. | 登録日 | 2019-04-04 | 公開日 | 2019-10-16 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | 主引用文献 | The Architecture of Talin1 Reveals an Autoinhibition Mechanism. Cell, 179, 2019
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8CRJ
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![BU of 8crj by Molmil](/molmil-images/mine/8crj) | Crystal structure of LplA1 in complex with lipoyl-AMP (Listeria monocytogenes) | 分子名称: | 1,2-ETHANEDIOL, 5'-O-[(R)-({5-[(3R)-1,2-DITHIOLAN-3-YL]PENTANOYL}OXY)(HYDROXY)PHOSPHORYL]ADENOSINE, GLYCEROL, ... | 著者 | Dienemann, J.-N, Chen, S.-Y, Hitzenberger, M, Sievert, M.L, Hacker, S.M, Prigge, S.T, Zacharias, M, Groll, M, Sieber, S.A. | 登録日 | 2023-03-08 | 公開日 | 2023-06-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A Chemical Proteomic Strategy Reveals Inhibitors of Lipoate Salvage in Bacteria and Parasites. Angew.Chem.Int.Ed.Engl., 62, 2023
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8CRL
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![BU of 8crl by Molmil](/molmil-images/mine/8crl) | Crystal structure of LplA1 in complex with the inhibitor C3 (Listeria monocytogenes) | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, SODIUM ION, ... | 著者 | Dienemann, J.-N, Chen, S.-Y, Hitzenberger, M, Sievert, M.L, Hacker, S.M, Prigge, S.T, Zacharias, M, Groll, M, Sieber, S.A. | 登録日 | 2023-03-08 | 公開日 | 2023-06-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A Chemical Proteomic Strategy Reveals Inhibitors of Lipoate Salvage in Bacteria and Parasites. Angew.Chem.Int.Ed.Engl., 62, 2023
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8CRI
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![BU of 8cri by Molmil](/molmil-images/mine/8cri) | Crystal structure of LplA1 in complex with lipoic acid (Listeria monocytogenes) | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, LIPOIC ACID, ... | 著者 | Dienemann, J.-N, Chen, S.-Y, Hitzenberger, M, Sievert, M.L, Hacker, S.M, Prigge, S.T, Zacharias, M, Groll, M, Sieber, S.A. | 登録日 | 2023-03-08 | 公開日 | 2023-06-07 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A Chemical Proteomic Strategy Reveals Inhibitors of Lipoate Salvage in Bacteria and Parasites. Angew.Chem.Int.Ed.Engl., 62, 2023
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2YGD
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![BU of 2ygd by Molmil](/molmil-images/mine/2ygd) | Molecular architectures of the 24meric eye lens chaperone alphaB- crystallin elucidated by a triple hybrid approach | 分子名称: | ALPHA-CRYSTALLIN B CHAIN | 著者 | Braun, N, Zacharias, M, Peschek, J, Kastenmueller, A, Zou, J, Hanzlik, M, Haslbeck, M, Rappsilber, J, Buchner, J, Weinkauf, S. | 登録日 | 2011-04-13 | 公開日 | 2011-12-07 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (9.4 Å) | 主引用文献 | Multiple Molecular Architectures of the Eye Lens Chaperone Alpha Beta-Crystallin Elucidated by a Triple Hybrid Approach Proc.Natl.Acad.Sci.USA, 108, 2011
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4CZ4
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![BU of 4cz4 by Molmil](/molmil-images/mine/4cz4) | HP24stab derived from the villin headpiece subdomain | 分子名称: | VILLIN-1 | 著者 | Hocking, H, Haese, F, Madl, T, Zacharias, M, Rief, M, Zoldak, G. | 登録日 | 2014-04-16 | 公開日 | 2015-02-18 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | A Compact Native 24-Residue Supersecondary Structure Derived from the Villin Headpiece Subdomain. Biophys.J., 108, 2015
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4CZ3
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![BU of 4cz3 by Molmil](/molmil-images/mine/4cz3) | HP24wt derived from the villin headpiece subdomain | 分子名称: | VILLIN-1 | 著者 | Hocking, H, Haese, F, Madl, T, Zacharias, M, Rief, M, Zoldak, G. | 登録日 | 2014-04-16 | 公開日 | 2015-02-18 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | A Compact Native 24-Residue Supersecondary Structure Derived from the Villin Headpiece Subdomain. Biophys.J., 108, 2015
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4LAV
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![BU of 4lav by Molmil](/molmil-images/mine/4lav) | Crystal Structure Analysis of FKBP52, Crystal Form II | 分子名称: | Peptidyl-prolyl cis-trans isomerase FKBP4, SULFATE ION | 著者 | Bracher, A, Kozany, C, Haehle, A, Wild, P, Zacharias, M, Hausch, F. | 登録日 | 2013-06-20 | 公開日 | 2013-08-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge. J.Mol.Biol., 425, 2013
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4LAY
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![BU of 4lay by Molmil](/molmil-images/mine/4lay) | Crystal Structure Analysis of FKBP52, Complex with I63 | 分子名称: | Peptidyl-prolyl cis-trans isomerase FKBP4, {3-[(1R)-3-(3,4-dimethoxyphenyl)-1-({[(2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidin-2-yl]carbonyl}oxy)propyl]phenoxy}acetic acid | 著者 | Bracher, A, Kozany, C, Haehle, A, Wild, P, Zacharias, M, Hausch, F. | 登録日 | 2013-06-20 | 公開日 | 2013-08-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge. J.Mol.Biol., 425, 2013
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4LAW
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![BU of 4law by Molmil](/molmil-images/mine/4law) | Crystal Structure Analysis of FKBP52, Crystal Form III | 分子名称: | DIMETHYL SULFOXIDE, Peptidyl-prolyl cis-trans isomerase FKBP4 | 著者 | Bracher, A, Kozany, C, Haehle, A, Wild, P, Zacharias, M, Hausch, F. | 登録日 | 2013-06-20 | 公開日 | 2013-08-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge. J.Mol.Biol., 425, 2013
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4IQY
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![BU of 4iqy by Molmil](/molmil-images/mine/4iqy) | Crystal structure of the human protein-proximal ADP-ribosyl-hydrolase MacroD2 | 分子名称: | MAGNESIUM ION, O-acetyl-ADP-ribose deacetylase MACROD2, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | 著者 | Jankevicius, G, Hassler, M, Golia, B, Rybin, V, Zacharias, M, Timinszky, G, Ladurner, A.G. | 登録日 | 2013-01-14 | 公開日 | 2013-03-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | A family of macrodomain proteins reverses cellular mono-ADP-ribosylation. Nat.Struct.Mol.Biol., 20, 2013
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6T1R
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![BU of 6t1r by Molmil](/molmil-images/mine/6t1r) | Pseudo-atomic model of a 16-mer assembly of reduced recombinant human alphaA-crystallin (non domain swapped configuration) | 分子名称: | Alpha-crystallin A chain | 著者 | Peters, C, Kaiser, C.J.O, Weinkauf, S, Zacharias, M, Buchner, J. | 登録日 | 2019-10-05 | 公開日 | 2019-12-11 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (9.8 Å) | 主引用文献 | The structure and oxidation of the eye lens chaperone alpha A-crystallin. Nat.Struct.Mol.Biol., 26, 2019
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4LAX
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![BU of 4lax by Molmil](/molmil-images/mine/4lax) | Crystal Structure Analysis of FKBP52, Complex with FK506 | 分子名称: | 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Bracher, A, Kozany, C, Haehle, A, Wild, P, Zacharias, M, Hausch, F. | 登録日 | 2013-06-20 | 公開日 | 2013-08-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.007 Å) | 主引用文献 | Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge. J.Mol.Biol., 425, 2013
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6SM1
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![BU of 6sm1 by Molmil](/molmil-images/mine/6sm1) | Wild type immunoglobulin light chain (WT-1) | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, Immunoglobulin lambda variable 2-14, ... | 著者 | Kazman, P, Vielberg, M.-T, Cendales, M.D.P, Hunziger, L, Weber, B, Hegenbart, U, Zacharias, M, Koehler, R, Schoenland, S, Groll, M, Buchner, J. | 登録日 | 2019-08-21 | 公開日 | 2020-03-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Fatal amyloid formation in a patient's antibody light chain is caused by a single point mutation. Elife, 9, 2020
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6SM2
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![BU of 6sm2 by Molmil](/molmil-images/mine/6sm2) | Mutant immunoglobulin light chain causing amyloidosis (Pat-1) | 分子名称: | Pat-1 | 著者 | Kazman, P, Vielberg, M.-T, Cendales, M.D.P, Hunziger, L, Weber, B, Hegenbart, U, Zacharias, M, Koehler, R, Schoenland, S, Groll, M, Buchner, J. | 登録日 | 2019-08-21 | 公開日 | 2020-03-18 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Fatal amyloid formation in a patient's antibody light chain is caused by a single point mutation. Elife, 9, 2020
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7ZKY
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![BU of 7zky by Molmil](/molmil-images/mine/7zky) | |
8OOI
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![BU of 8ooi by Molmil](/molmil-images/mine/8ooi) | Full composite cryo-EM map of p97/VCP in ADP.Pi state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Cheng, T.C, Sakata, E, Schuetz, A.K. | 登録日 | 2023-04-05 | 公開日 | 2024-01-31 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.61 Å) | 主引用文献 | Characterizing ATP processing by the AAA+ protein p97 at the atomic level. Nat.Chem., 16, 2024
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3DEL
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![BU of 3del by Molmil](/molmil-images/mine/3del) | |
1Z30
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![BU of 1z30 by Molmil](/molmil-images/mine/1z30) | NMR structure of the apical part of stemloop D from cloverleaf 1 of bovine enterovirus 1 RNA | 分子名称: | 5'-R(*GP*GP*CP*GP*UP*UP*CP*GP*UP*UP*AP*GP*AP*AP*CP*GP*UP*C)-3' | 著者 | Ihle, Y, Ohlenschlager, O, Duchardt, E, Ramachandran, R, Gorlach, M. | 登録日 | 2005-03-10 | 公開日 | 2005-04-26 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | A novel cGUUAg tetraloop structure with a conserved yYNMGg-type backbone conformation from cloverleaf 1 of bovine enterovirus 1 RNA Nucleic Acids Res., 33, 2005
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3N26
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![BU of 3n26 by Molmil](/molmil-images/mine/3n26) | Cpn0482 : the arginine binding protein from the periplasm of chlamydia Pneumoniae | 分子名称: | ARGININE, Amino acid ABC transporter, periplasmic amino acid-binding protein | 著者 | Petit, P, Garcia, C, Vuillard, L, Soriani, M, Grandi, G, Marseilles Structural Genomics Program AFMB (MSGP), Marseilles Structural Genomics Program @ AFMB (MSGP) | 登録日 | 2010-05-17 | 公開日 | 2010-06-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Exploiting antigenic diversity for vaccine design: the Chlamydia ArtJ paradigm. J.Biol.Chem., 2010
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7NE3
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![BU of 7ne3 by Molmil](/molmil-images/mine/7ne3) | Human TET2 in complex with favourable DNA substrate. | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*AP*CP*AP*GP*GP*(5CM)P*GP*CP*CP*TP*G)-3'), ... | 著者 | Rafalski, D, Bochtler, M. | 登録日 | 2021-02-03 | 公開日 | 2022-03-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function. Sci Adv, 8, 2022
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7NE6
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7OVT
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![BU of 7ovt by Molmil](/molmil-images/mine/7ovt) | |
7BGH
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6ZMD
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![BU of 6zmd by Molmil](/molmil-images/mine/6zmd) | Crystal structure of HYPE covalently tethered to BiP bound to AMP-PNP | 分子名称: | Endoplasmic reticulum chaperone BiP, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Fauser, J, Gulen, B, Pett, C, Hedberg, C, Itzen, A, Pogenberg, V. | 登録日 | 2020-07-02 | 公開日 | 2021-04-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Specificity of AMPylation of the human chaperone BiP is mediated by TPR motifs of FICD. Nat Commun, 12, 2021
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