3HCS
 
 | | Crystal structure of the N-terminal domain of TRAF6 | | 分子名称: | TNF receptor-associated factor 6, ZINC ION | | 著者 | Yin, Q, Lin, S.-C, Lamothe, B, Lu, M, Lo, Y.-C, Hura, G, Zheng, L, Rich, R.L, Campos, A.D, Myszka, D.G, Lenardo, M.J, Darnay, B.G, Wu, H. | | 登録日 | 2009-05-06 | | 公開日 | 2009-05-26 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | E2 interaction and dimerization in the crystal structure of TRAF6.
Nat.Struct.Mol.Biol., 16, 2009
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3HCT
 | | Crystal structure of TRAF6 in complex with Ubc13 in the P1 space group | | 分子名称: | TNF receptor-associated factor 6, Ubiquitin-conjugating enzyme E2 N, ZINC ION | | 著者 | Yin, Q, Lin, S.-C, Lamothe, B, Lu, M, Lo, Y.-C, Hura, G, Zheng, L, Rich, R.L, Campos, A.D, Myszka, D.G, Lenardo, M.J, Darnay, B.G, Wu, H. | | 登録日 | 2009-05-06 | | 公開日 | 2009-05-26 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | E2 interaction and dimerization in the crystal structure of TRAF6.
Nat.Struct.Mol.Biol., 16, 2009
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3HCU
 | | Crystal structure of TRAF6 in complex with Ubc13 in the C2 space group | | 分子名称: | TNF receptor-associated factor 6, Ubiquitin-conjugating enzyme E2 N, ZINC ION | | 著者 | Yin, Q, Lin, S.-C, Lamothe, B, Lu, M, Lo, Y.-C, Hura, G, Zheng, L, Rich, R.L, Campos, A.D, Myszka, D.G, Lenardo, M.J, Darnay, B.G, Wu, H. | | 登録日 | 2009-05-06 | | 公開日 | 2009-05-26 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | E2 interaction and dimerization in the crystal structure of TRAF6.
Nat.Struct.Mol.Biol., 16, 2009
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3KNV
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4L5Q
 | | Crystal structure of p202 HIN1 | | 分子名称: | Interferon-activable protein 202 | | 著者 | Yin, Q, Tian, Y, Wu, H. | | 登録日 | 2013-06-11 | | 公開日 | 2013-07-31 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation.
Cell Rep, 4, 2013
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4L5R
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4L5S
 | | p202 HIN1 in complex with 12-mer dsDNA | | 分子名称: | 12-mer DNA, Interferon-activable protein 202, SULFATE ION | | 著者 | Yin, Q, Tian, Y, Wu, H. | | 登録日 | 2013-06-11 | | 公開日 | 2013-08-14 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | | 主引用文献 | Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation.
Cell Rep, 4, 2013
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4L5T
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7TDQ
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6VKJ
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3JBL
 | | Cryo-EM Structure of the Activated NAIP2/NLRC4 Inflammasome Reveals Nucleated Polymerization | | 分子名称: | NLR family CARD domain-containing protein 4 | | 著者 | Zhang, L, Chen, S, Ruan, J, Wu, J, Tong, A.B, Yin, Q, Li, Y, David, L, Lu, A, Wang, W.L, Marks, C, Ouyang, Q, Zhang, X, Mao, Y, Wu, H. | | 登録日 | 2015-09-05 | | 公開日 | 2015-10-21 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.
Science, 350, 2015
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3J63
 | | Unified assembly mechanism of ASC-dependent inflammasomes | | 分子名称: | Apoptosis-associated speck-like protein containing a CARD | | 著者 | Lu, A, Magupalli, V.G, Ruan, J, Yin, Q, Atianand, M.K, Vos, M, Schroder, G.F, Fitzgerald, K.A, Wu, H, Egelman, E.H. | | 登録日 | 2013-12-05 | | 公開日 | 2014-03-26 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes.
Cell(Cambridge,Mass.), 156, 2014
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7M1S
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6OE9
 | | Crystal structure of p204 HIN1 domain | | 分子名称: | GLYCEROL, Interferon-activable protein 204, SULFATE ION | | 著者 | Tian, Y, Yin, Q. | | 登録日 | 2019-03-27 | | 公開日 | 2019-07-10 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Structural analysis of the HIN1 domain of interferon-inducible protein 204.
Acta Crystallogr.,Sect.F, 75, 2019
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5FNA
 | | Cryo-EM reconstruction of caspase-1 CARD | | 分子名称: | Caspase-1 | | 著者 | Li, Y, Lu, A, Schmidt, F.I, Yin, Q, Chen, S, Fu, T.M, Tong, A.B, Ploegh, H.L, Mao, Y, Wu, H. | | 登録日 | 2015-11-11 | | 公開日 | 2016-03-30 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Molecular Basis of Caspase-1 Polymerization and its Inhibition by a Novel Capping Mechanism
Nat.Struct.Mol.Biol., 23, 2016
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7TWD
 | | Structure of AAGAB C-terminal dimerization domain | | 分子名称: | Alpha- and gamma-adaptin-binding protein p34, PHOSPHATE ION | | 著者 | Tian, Y, Yin, Q. | | 登録日 | 2022-02-07 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Oligomer-to-monomer transition underlies the chaperone function of AAGAB in AP1/AP2 assembly.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8J17
 | | Crystal structure of IsPETase variant | | 分子名称: | Poly(ethylene terephthalate) hydrolase | | 著者 | Yin, Q.D, Wang, Y.X. | | 登録日 | 2023-04-12 | | 公開日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Efficient polyethylene terephthalate biodegradation by an engineered Ideonella sakaiensis PETase with a fixed substrate-binding W156 residue
Green Chem, 2013
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4F9G
 | | Crystal structure of STING complex with Cyclic di-GMP. | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Transmembrane protein 173 | | 著者 | Kabaleeswaran, V, Wu, H. | | 登録日 | 2012-05-18 | | 公開日 | 2012-07-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING.
Mol.Cell, 46, 2012
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4F9E
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6FWB
 | | Crystal structure of Mat2A at 1.79 Angstron resolution | | 分子名称: | GLYCEROL, S-adenosylmethionine synthase isoform type-2, SODIUM ION, ... | | 著者 | Zhou, A, Wei, Z, Bai, J, Wang, H. | | 登録日 | 2018-03-06 | | 公開日 | 2019-03-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Identification of a natural inhibitor of methionine adenosyltransferase 2A regulating one-carbon metabolism in keratinocytes.
Ebiomedicine, 39, 2019
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8ENT
 | | Interleukin-21 signaling complex with IL-21R and IL-2Rg | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Abhiraman, G.C, Jude, K.M, Garcia, K.C. | | 登録日 | 2022-09-30 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | | 主引用文献 | A structural blueprint for interleukin-21 signal modulation.
Cell Rep, 42, 2023
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8F5I
 | | SARS-CoV-2 S2 helix epitope scaffold bound by antibody DH1057.1 | | 分子名称: | DH1057.1 HC, DH1057.1 LC, Specialized acyl carrier protein, ... | | 著者 | Kapingidza, A.B, Wrapp, D, Winters, K, Azoitei, M.L. | | 登録日 | 2022-11-14 | | 公開日 | 2023-10-11 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Engineered immunogens to elicit antibodies against conserved coronavirus epitopes.
Nat Commun, 14, 2023
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8F5H
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3OQ9
 | | Structure of the FAS/FADD death domain assembly | | 分子名称: | Protein FADD, Tumor necrosis factor receptor superfamily member 6 | | 著者 | Kabaleeswaran, V, Wu, H. | | 登録日 | 2010-09-02 | | 公開日 | 2010-10-13 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (6.8 Å) | | 主引用文献 | The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations.
Nat.Struct.Mol.Biol., 17, 2010
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3RIU
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